Genomes and Genes
Peter T Campbell
Affiliation: Fred Hutchinson Cancer Research Center
- Fine particulate matter (PM₂.₅) air pollution and immune status among women in the Seattle areaLori Williams
Department of Epidemiology, School of Public Health, University of Washington, Seattle, Washington, USA
Arch Environ Occup Health 66:155-65. 2011..If additional studies confirm our findings, then future health effect assessments for PM₂.₅ should consider changes in cellular immunity as an endpoint that may lead to overt clinical disease...
- Exogenous hormones and colorectal cancer risk in Canada: associations stratified by clinically defined familial risk of cancerPeter T Campbell
Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
Cancer Causes Control 18:723-33. 2007..This work assessed associations between colorectal cancer risk and postmenopausal/contraceptive hormones; subgroup analyses included women with a clinically defined family history of cancer...
- Excess body weight and colorectal cancer risk in Canada: associations in subgroups of clinically defined familial risk of cancerPeter T Campbell
Cancer Prevention, Fred Hutchinson Cancer Research Center, M4 B402, Seattle, WA 98109, USA
Cancer Epidemiol Biomarkers Prev 16:1735-44. 2007....
- Proximity to traffic, inflammation, and immune function among women in the Seattle, Washington, areaLori A Williams
Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, Washington 98109 1024, USA
Environ Health Perspect 117:373-8. 2009..Traffic-related air pollution has been associated with adverse health outcomes, and the immune system may be a biologic mediator of health effects...
- Survival after inflammatory bowel disease-associated colorectal cancer in the Colon Cancer Family RegistryScott V Adams
Cancer Prevention, Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
World J Gastroenterol 19:3241-8. 2013..To investigate the survival of individuals with colorectal cancer (CRC) with inflammatory bowel disease (IBD-associated CRC) compared to that of individuals without IBD diagnosed with CRC...
- No reduction in C-reactive protein following a 12-month randomized controlled trial of exercise in men and womenKristin L Campbell
Cancer Prevention Program, The Fred Hutchinson Cancer Research Center, Public Health Sciences, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 17:1714-8. 2008....
- Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysisUlrike Peters
Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Gastroenterology 144:799-807.e24. 2013..Heritable factors contribute to the development of colorectal cancer. Identifying the genetic loci associated with colorectal tumor formation could elucidate the mechanisms of pathogenesis...
- A yearlong exercise intervention decreases CRP among obese postmenopausal womenPeter T Campbell
Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Med Sci Sports Exerc 41:1533-9. 2009..To investigate the effect of a yearlong moderate-intensity aerobic exercise intervention on C-reactive protein (CRP), serum amyloid A (SAA), and interleukin 6 (IL-6) among overweight or obese postmenopausal women...
- IκBKβ and NFκB1, NSAID use and risk of colorectal cancer in the Colon Cancer Family RegistryBrenna L Seufert
Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Carcinogenesis 34:79-85. 2013..The SNPs identified here should be considered for future functional studies and may be useful in designing a pharmacogenetic approach to preventive NSAID use...
- A pooled analysis of smoking and colorectal cancer: timing of exposure and interactions with environmental factorsJian Gong
Public Health Sciences Division, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA 98109, USA
Cancer Epidemiol Biomarkers Prev 21:1974-85. 2012..What is unclear, however, is the impact of quitting smoking on risk attenuation and whether other risk factors for CRC modify this association...
- Genome-wide search for gene-gene interactions in colorectal cancerShuo Jiao
Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
PLoS ONE 7:e52535. 2012..1) (nominal combined p = 2.51×10(-6); Bonferroni adjusted p = 0.03). Our study represents the first comprehensive search for GxG in CRC, and our results may provide new insight into the genetic etiology of CRC...
- Prediagnostic non-steroidal anti-inflammatory drug use and survival after diagnosis of colorectal cancerAnna E Coghill
Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Gut 60:491-8. 2011..The role of prediagnostic NSAID use was therefore examined in relation to colorectal cancer-specific survival among cases from the Seattle Colon Cancer Family Registry (Seattle Colon CFR)...
- Association between colorectal cancer susceptibility loci and survival time after diagnosis with colorectal cancerAmanda I Phipps
Cancer Prevention Program, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
Gastroenterology 143:51-4.e4. 2012..05-1.30; P = .005). Other SNPs were not associated significantly with survival. Common germline variations might be prognostic factors for patients with CRC. A variant in SMAD7 could affect progression of CRC...
- Dietary patterns and risk of incident gastric adenocarcinomaPeter T Campbell
Division of Preventive Oncology, Cancer Care Ontario, Toronto, Ontario, Canada
Am J Epidemiol 167:295-304. 2008....
- Effect of exercise on in vitro immune function: a 12-month randomized, controlled trial among postmenopausal womenPeter T Campbell
Fred Hutchinson Cancer Research Center, Cancer Prevention Program, Seattle, WA 98109 1024, USA
J Appl Physiol (1985) 104:1648-55. 2008..This 12-mo randomized, controlled trial showed no effect of aerobic exercise on in vitro immune function, despite excellent retention, high adherence, and demonstrable efficacy of the exercise intervention...
- Cytochrome P450 17A1 and catechol O-methyltransferase polymorphisms and age at Lynch syndrome colon cancer onset in NewfoundlandPeter T Campbell
Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Division of Preventive Oncology, Cancer Care Ontario, Toronto, Ontario, Canada
Clin Cancer Res 13:3783-8. 2007..g., postmenopausal hormones); we hypothesized that polymorphisms which influence endogenous hormones would therefore modify age at colon cancer onset among Lynch syndrome mutation carriers...
- Utility of proxy versus index respondent information in a population-based case-control study of rapidly fatal cancersPeter T Campbell
Research Unit, Division of Preventive Oncology, Cancer Care Ontario, and Department of Public Health Sciences, University of Toronto, Toronto, Canada
Ann Epidemiol 17:253-7. 2007..This work provides an empirical assessment of the usefulness of obtaining exposure data from proxy respondents...
- Physical activity and stomach cancer risk: the influence of intensity and timing during the lifetimePeter T Campbell
Division of Preventive Oncology, Cancer Care Ontario, 620 University Avenue, Toronto, Ont, Canada M5G 2L7
Eur J Cancer 43:593-600. 2007..Increased strenuous physical activity, throughout the lifespan, was associated with decreased risk of incident stomach cancer...