Linda BuckSummaryAffiliation: Fred Hutchinson Cancer Research Center Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Olfactory receptors and odor coding in mammalsLinda B Buck
Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Nutr Rev 62:S184-8; discussion S224-41. 2004..Another olfactory structure in the nasal septum of animals, the vomeronasal organ, has two additional receptor families that detect pheromones and induce hormonal and behavioral responses through a different projection to the brain...- Combinatorial effects of odorant mixes in olfactory cortexZhihua Zou
Howard Hughes Medical Institute and Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA
Science 311:1477-81. 2006..These findings may explain why odorant mixtures can elicit novel odor percepts in humans... - Olfactory axon pathfinding: who is the pied piper?Rajesh Ranganathan
Howard Hughes Medical Institute, Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA
Neuron 35:599-600. 2002..use OR minigenes that coexpress histochemical markers and show that the determinants in the sensory neurons required to generate the stereotyped olfactory bulb map are the same as those needed for appropriate expression of the OR... - Unraveling smellLinda B Buck
Howard Hughes Medical Institute, Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Harvey Lect 101:117-34. 2005 - The human olfactory receptor gene familyBettina Malnic
Howard Hughes Medical Institute, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA
Proc Natl Acad Sci U S A 101:2584-9. 2004..Moreover, many loci encode only one or a few subfamilies, suggesting that different parts of the genome may, to some extent, be involved in the detection of different types of odorant structural motifs... - Odor maps in the olfactory cortexZhihua Zou
Howard Hughes Medical Institute and Divisions of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Proc Natl Acad Sci U S A 102:7724-9. 2005..Structurally related odorants have highly related representations, suggesting an underlying logic to the mapping of odor identities in the cortex... - Feedback loops link odor and pheromone signaling with reproductionUlrich Boehm
Howard Hughes Medical Institute, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
Cell 123:683-95. 2005..These studies reveal a complex interplay between reproduction and other functions in which GnRH neurons appear to integrate information from multiple sources and modulate a variety of brain functions... - The search for odorant receptorsLinda B Buck
Howard Hughes Medical Institute, Basic Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, Washington 98109, USA
Cell 116:S117-9, 1 p following S119. 2004 - Unraveling the sense of smell (Nobel lecture)Linda B Buck
Howard Hughes Medical Institute, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109-1024, USA
Angew Chem Int Ed Engl 44:6128-40. 2005 - The mouse olfactory receptor gene familyPaul A Godfrey
Howard Hughes Medical Institute, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA
Proc Natl Acad Sci U S A 101:2156-61. 2004..This finding suggests that humans and mice recognize many of the same odorant structural motifs, but mice may be superior in odor sensitivity and discrimination... - A second class of chemosensory receptors in the olfactory epitheliumStephen D Liberles
Howard Hughes Medical Institute, Basic Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, Washington 98109, USA
Nature 442:645-50. 2006..The evolutionary conservation of the TAAR family suggests a chemosensory function distinct from odorant receptors. Ligands identified for TAARs thus far suggest a function associated with the detection of social cues... - [The 2004 Nobel Prize for Physiology or Medicine for research into smell receptors and the organization of the olfactory system]J P H Burbach
Universitair Medisch Centrum Utrecht, Rudolf Magnus Instituut voor Neurowetenschappen, afd Farmacologie en Anatomie, Universiteitsweg 110, 3584 CG Utrecht
Ned Tijdschr Geneeskd 148:2576-9. 2004.... - Nobel Prize in Physiology or Medicine, 2004. Richard Axel and Linda B BuckRichard Axel
Indian J Physiol Pharmacol 49:122. 2005
Research Grants
- MOLECULAR BASIS OF OLFACTORY DISCRIMINATIONLinda Buck; Fiscal Year: 2005....
- Molecular Analysis of Olfactory Sensory ImputsLinda Buck; Fiscal Year: 2005....
- Molecular mechanisms of olfaction in mammalsLinda Buck; Fiscal Year: 2009..Project Narrative The mechanisms that the brain uses to perceive the world around us and to learn and remember are unknown. We will investigate the mechanisms that underlie the sense of smell to gain insight into these questions. ..
- Molecular mechanisms of olfaction in mammalsLinda B Buck; Fiscal Year: 2010..Project Narrative The mechanisms that the brain uses to perceive the world around us and to learn and remember are unknown. We will investigate the mechanisms that underlie the sense of smell to gain insight into these questions. ..
- Molecular mechanisms of olfaction in mammalsLinda Buck; Fiscal Year: 2009..Project Narrative The mechanisms that the brain uses to perceive the world around us and to learn and remember are unknown. We will investigate the mechanisms that underlie the sense of smell to gain insight into these questions. ..
- MOLECULAR BASIS OF OLFACTORY DISCRIMINATIONLinda Buck; Fiscal Year: 1993..3) Investigate the developmental acquisition of these organizational features in order to determine the mechanisms by which they are established...
- MOLECULAR BASIS OF OLFACTORY DISCRIMINATIONLinda Buck; Fiscal Year: 2000..Finally, we will use the isolated OR genes we have isolated and the information we have accumulated on human OR genes to analyze the extent of variation in OR repertoire in the human population. ..
- Molecular mechanisms of olfaction in mammalsLinda B Buck; Fiscal Year: 2011..Project Narrative The mechanisms that the brain uses to perceive the world around us and to learn and remember are unknown. We will investigate the mechanisms that underlie the sense of smell to gain insight into these questions. ..