Research Topics
| Catherine A BlishSummaryAffiliation: Fred Hutchinson Cancer Research Center Country: USA Publications
| Collaborators
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Detail Information
Publications
Comparative immunogenicity of subtype a Human Immunodeficiency Virus type 1 envelope exhibiting differential exposure of conserved neutralization epitopesCatherine A Blish
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
J Virol 84:2573-84. 2010....
Transmission of HIV-1 in the face of neutralizing antibodiesCatherine A Blish
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
Curr HIV Res 5:578-87. 2007....- Hormonal contraception and HIV-1 transmissionCatherine A Blish
Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, Seattle, WA 98109, USA
Am J Reprod Immunol 65:302-7. 2011..It is clear that hormonal contraceptives are not protective against HIV-1 infection and that dual protection with condoms should be the goal for women using hormonal contraception... - Genital Inflammation Predicts HIV-1 Shedding Independent of Plasma Viral Load and Systemic InflammationCatherine A Blish
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
J Acquir Immune Defic Syndr 61:436-40. 2012..Thus, efforts to decrease HIV-1 transmission must take into account the role of local inflammation, which is not necessarily reflected in plasma measurements... - Cellular immune responses and susceptibility to HIV-1 superinfection: a case-control studyCatherine A Blish
Division of Human Biology, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington, USA
AIDS 26:643-6. 2012.... - Cross-subtype neutralization sensitivity despite monoclonal antibody resistance among early subtype A, C, and D envelope variants of human immunodeficiency virus type 1Catherine A Blish
Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave North, Seattle, WA 98109 1024, USA
J Virol 83:7783-8. 2009..However, significant cross-subtype neutralization by plasma was observed, indicating that there may be other epitopes, not yet defined by the limited available MAbs, which could be recognized more broadly... - Breadth of neutralizing antibody response to human immunodeficiency virus type 1 is affected by factors early in infection but does not influence disease progressionAnne Piantadosi
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
J Virol 83:10269-74. 2009..Thus, a broad NAb response results from a high level of antigenic stimulation early in infection, which likely accounts for prior observations that greater NAb response breadth is associated with a higher viral load later in infection... - Human immunodeficiency virus type 1 superinfection occurs despite relatively robust neutralizing antibody responsesCatherine A Blish
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
J Virol 82:12094-103. 2008..These data indicate that preventing infection by vaccination will likely require broader and more potent NAb responses than those found in HIV-1-infected individuals... - Enhancing exposure of HIV-1 neutralization epitopes through mutations in gp41Catherine A Blish
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
PLoS Med 5:e9. 2008..Using a naturally occurring HIV-1 Envelope (Env) variant as a template, we sought to identify features of Env that would enhance exposure of conserved HIV-1 epitopes... - The breadth and potency of passively acquired human immunodeficiency virus type 1-specific neutralizing antibodies do not correlate with the risk of infant infectionJohn B Lynch
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
J Virol 85:5252-61. 2011.... - The role of amino acid changes in the human immunodeficiency virus type 1 transmembrane domain in antibody binding and neutralizationErica Lovelace
Divisions of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Virology 421:235-44. 2011..This finding suggests that antibody neutralization may occur through a multi-step pathway that includes distinct changes in envelope conformation that may affect binding but not neutralization susceptibility... - HIV-1 subtype A envelope variants from early in infection have variable sensitivity to neutralization and to inhibitors of viral entryCatherine A Blish
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
AIDS 21:693-702. 2007..An effective HIV-1 vaccine or microbicide must block the transmitted virus variants that initially establish a new infection; consequently, it is critical that such viruses be isolated and characterized... - Changes in plasma cytokines after treatment of ascaris lumbricoides infection in individuals with HIV-1 infectionCatherine A Blish
Division of Human Biology, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA 98104, USA
J Infect Dis 201:1816-21. 2010..Treatment of A. lumbricoides co-infection may delay HIV-1 disease progression by reducing helminth-induced, IL-10-mediated immunosuppression...