SUSAN BIGGINS

Summary

Affiliation: Fred Hutchinson Cancer Research Center
Country: USA

Publications

  1. pmc Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces cerevisiae
    S Biggins
    Department of Physiology, University of California, San Francisco, 94143, USA
    Genetics 159:453-70. 2001
  2. pmc The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint
    S Biggins
    Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Genes Dev 15:3118-29. 2001
  3. ncbi request reprint Captivating capture: how microtubules attach to kinetochores
    Sue Biggins
    Division of Basic Sciences, Fred Hutchinson Cancer Research Center, PO Box 19024, 1100 Fairview Ave North, A2 168, Seattle, WA 98109 1024, USA
    Curr Biol 13:R449-60. 2003
  4. pmc The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast
    S Biggins
    Department of Physiology, University of California, San Francisco, California 94143 0444, USA
    Genes Dev 13:532-44. 1999
  5. ncbi request reprint Sister chromatid cohesion in mitosis
    S Biggins
    513 Parnassus Avenue, Box 0444, Department of Physiology, University of California, San Francisco, San Francisco, California 94143 0444, USA
    Curr Opin Genet Dev 9:230-6. 1999

Research Grants

  1. Regulation of Chromosome Segregation
    SUSAN BIGGINS; Fiscal Year: 2009
  2. Regulation of Chromosome Segregation
    SUSAN BIGGINS; Fiscal Year: 2010
  3. Regulation of Centromeric Chromatin
    SUSAN BIGGINS; Fiscal Year: 2010
  4. Regulation of Chromosome Segregation
    SUSAN BIGGINS; Fiscal Year: 2006
  5. Regulation of Centromeric Chromatin
    SUSAN BIGGINS; Fiscal Year: 2011

Detail Information

Publications5

  1. pmc Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces cerevisiae
    S Biggins
    Department of Physiology, University of California, San Francisco, 94143, USA
    Genetics 159:453-70. 2001
    ..We also report an initial characterization of phenotypes associated with the SMT3/SUMO gene and the isolation of WSS1, a high-copy smt3 suppressor...
  2. pmc The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint
    S Biggins
    Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Genes Dev 15:3118-29. 2001
    ..Ipl1p localizes at or near kinetochores during mitosis, and we propose that Ipl1p is required to monitor tension at the kinetochore...
  3. ncbi request reprint Captivating capture: how microtubules attach to kinetochores
    Sue Biggins
    Division of Basic Sciences, Fred Hutchinson Cancer Research Center, PO Box 19024, 1100 Fairview Ave North, A2 168, Seattle, WA 98109 1024, USA
    Curr Biol 13:R449-60. 2003
    ..Here we discuss current progress in determining how kinetochores assemble and attach to MTs during mitosis as well as how they correct errors...
  4. pmc The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast
    S Biggins
    Department of Physiology, University of California, San Francisco, California 94143 0444, USA
    Genes Dev 13:532-44. 1999
    ..Because aurora2 has been implicated in oncogenesis, defects in kinetochore function may contribute to genetic instability in human tumors...
  5. ncbi request reprint Sister chromatid cohesion in mitosis
    S Biggins
    513 Parnassus Avenue, Box 0444, Department of Physiology, University of California, San Francisco, San Francisco, California 94143 0444, USA
    Curr Opin Genet Dev 9:230-6. 1999
    ..Proteins that induce and regulate the separation of sister chromatids have also been recently identified. (This review is an updated version of one that was published in Current Opinion in Cell Biology 1998, 10:769-775.)..

Research Grants15

  1. Regulation of Chromosome Segregation
    SUSAN BIGGINS; Fiscal Year: 2009
    ..Taken together, these studies should lead to a better understanding of chromosome segregation and the maintenance of genomic stability in all eukaryotes. ..
  2. Regulation of Chromosome Segregation
    SUSAN BIGGINS; Fiscal Year: 2010
    ..Taken together, these studies should lead to a better understanding of chromosome segregation and the maintenance of genomic stability in all eukaryotes. ..
  3. Regulation of Centromeric Chromatin
    SUSAN BIGGINS; Fiscal Year: 2010
    ..We are therefore studying the process of chromosome partitioning to daughter cells when they divide to understand the basis for a number of human diseases. ..
  4. Regulation of Chromosome Segregation
    SUSAN BIGGINS; Fiscal Year: 2006
    ..abstract_text> ..
  5. Regulation of Centromeric Chromatin
    SUSAN BIGGINS; Fiscal Year: 2011
    ..We are therefore studying the process of chromosome partitioning to daughter cells when they divide to understand the basis for a number of human diseases. ..