Research Topics
Genomes and Genes
| Parveen BhattiSummaryAffiliation: Fred Hutchinson Cancer Research Center Country: USA Publications
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Detail Information
Publications
Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumorsParveen Bhatti
Department of Health ad Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 18:1841-8. 2009..Although the results of this study provide some evidence that lead may cause glioblastoma multiforme and meningioma through mechanisms related to oxidative damage, the results must be confirmed in other populations...- Racial differences in the association between night shift work and melatonin levels among womenParveen Bhatti
Public Health Scienes Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Am J Epidemiol 177:388-93. 2013.... 
Nightshift work and risk of ovarian cancerParveen Bhatti
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
Occup Environ Med 70:231-7. 2013..We evaluated the association between self-reported nightshift work, a known circadian disruptor, and ovarian cancer in a population-based case-control study...- Invited commentary: Shift work and cancerParveen Bhatti
Program in Epidemiology, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Am J Epidemiol 176:760-3; discussion 764-5. 2012.... - Blood spots as an alternative to whole blood collection and the effect of a small monetary incentive to increase participation in genetic association studiesParveen Bhatti
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
BMC Med Res Methodol 9:76. 2009..However, dried blood spot collection, which is also a convenient method, offers a means of collecting peripheral blood samples from which analytes in addition to DNA can be obtained... - Risk of second primary thyroid cancer after radiotherapy for a childhood cancer in a large cohort study: an update from the childhood cancer survivor studyParveen Bhatti
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, UA
Radiat Res 174:741-52. 2010.... - Wood dust exposure and risk of lung cancerParveen Bhatti
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Occup Environ Med 68:599-604. 2011..We investigated whether a history of wood dust exposure through occupational and hobby-related activities was associated with increased lung cancer risk... - Novel breast cancer risk alleles and interaction with ionizing radiation among U.S. radiologic technologistsParveen Bhatti
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Radiat Res 173:214-24. 2010..Even though a complete understanding of the way(s) in which these variants may increase breast cancer risk remains elusive, this approach may yield clues for further investigation... - Comparison of occupational exposure assessment methods in a case-control study of lead, genetic susceptibility and risk of adult brain tumoursParveen Bhatti
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Occup Environ Med 68:4-9. 2011.... - Diagnostic X-ray examinations and increased chromosome translocations: evidence from three studiesParveen Bhatti
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Radiat Environ Biophys 49:685-92. 2010.... - Polymorphisms in estrogen biosynthesis and metabolism-related genes, ionizing radiation exposure, and risk of breast cancer among US radiologic technologistsAlice J Sigurdson
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Boulevard, EPS 7060, MSC 7238, Bethesda, MD, 20892 7238, USA
Breast Cancer Res Treat 118:177-84. 2009..06). We found suggestive evidence that common variants in selected estrogen metabolizing genes may modify the association between ionizing radiation exposure and breast cancer risk... 
Polymorphisms in apoptosis- and proliferation-related genes, ionizing radiation exposure, and risk of breast cancer among U.S. Radiologic TechnologistsAlice J Sigurdson
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, EPS 7092, MSC 7238, Bethesda, MD 20892 7238, USA
Cancer Epidemiol Biomarkers Prev 16:2000-7. 2007..For this reason, potential modification of the relationship between ionizing radiation exposure and breast cancer risk by polymorphic apoptosis gene variants have not been investigated among radiation-exposed women...- Nucleotide excision repair polymorphisms may modify ionizing radiation-related breast cancer risk in US radiologic technologistsPreetha Rajaraman
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892, USA
Int J Cancer 123:2713-6. 2008..1-21.3; EOR/Gy(AC/CC) = 0.6, 95% CI = <0, 4.6; p(het) = 0.01). These results suggest that common variants in nucleotide excision repair genes may modify the association between occupational radiation exposure and breast cancer risk... - Breast cancer risk polymorphisms and interaction with ionizing radiation among U.S. radiologic technologistsParveen Bhatti
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, MD 20892 7238, USA
Cancer Epidemiol Biomarkers Prev 17:2007-11. 2008..001). H19 is a maternally expressed imprinted mRNA that is closely involved in regulating the IGF2 gene and could exert its influence by this or by some other radiation-related pathway... - Routine diagnostic X-ray examinations and increased frequency of chromosome translocations among U.S. radiologic technologistsAlice J Sigurdson
Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, Radiation Epidemiology Branch, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
Cancer Res 68:8825-31. 2008..The slope estimate was consistent with expectation based on cytogenetic experience and atomic bomb survivor data... - Polymorphisms in oxidative stress and inflammation pathway genes, low-dose ionizing radiation, and the risk of breast cancer among US radiologic technologistsSara J Schonfeld
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, 6120 Executive Blvd MSC 7238, Bethesda, MD 20892, USA
Cancer Causes Control 21:1857-66. 2010..Polymorphic variation in oxidative stress and inflammatory-mediated pathway genes may modify radiation-related breast cancer risk... - Increased frequency of chromosome translocations associated with diagnostic x-ray examinationsParveen Bhatti
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, Bethesda, MD 20892, USA
Radiat Res 170:149-55. 2008..002 to 0.013; P = 0.01). Chromosome damage has been linked with elevated cancer risk, and we found that cumulative radiation exposure from medical X-ray examinations was associated with increased numbers of chromosome translocations... - Chemotherapy and thyroid cancer risk: a report from the childhood cancer survivor studyLene H S Veiga
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard EPS 7051, MSC 7238, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 21:92-101. 2012..We evaluated the chemotherapy-related risk of thyroid cancer in childhood cancer survivors and the possible joint effects of chemotherapy and radiotherapy... - Polymorphisms in DNA repair genes, ionizing radiation exposure and risk of breast cancer in U.S. Radiologic technologistsParveen Bhatti
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892 7238, USA
Int J Cancer 122:177-82. 2008..The suggestive evidence found for modification of radiation-related breast cancer risk for 5 of the 55 SNPs evaluated requires confirmation in larger studies of women with quantified radiation breast doses in the low-to-moderate range... - Absolute risk prediction of second primary thyroid cancer among 5-year survivors of childhood cancerStephanie A Kovalchik
National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
J Clin Oncol 31:119-27. 2013..We developed three absolute risk models for second primary thyroid cancer to assist with long-term clinical monitoring of childhood cancer survivors... - Thyroid nodules, polymorphic variants in DNA repair and RET-related genes, and interaction with ionizing radiation exposure from nuclear tests in KazakhstanAlice J Sigurdson
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892 7238, USA
Radiat Res 171:77-88. 2009..Other pathways such as genes in double-strand break repair, apoptosis and genes related to proliferation should also be pursued... - A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1)Gilles Thomas
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Nat Genet 41:579-84. 2009..1 (rs999737; P = 1.74 x 10(-7)) localizes to RAD51L1, a gene in the homologous recombination DNA repair pathway. We also confirmed associations with loci on chromosomes 2q35, 5p12, 5q11.2, 8q24, 10q26 and 16q12.1... - No evidence for differences in DNA damage assessed before and after a cancer diagnosisParveen Bhatti
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892 7238, USA
Cancer Epidemiol Biomarkers Prev 17:990-4. 2008..More work is needed to characterize the effect of cancer diagnosis on other phenotypic assays... - Sunlight, polymorphisms of vitamin D-related genes and risk of breast cancerBarbara J Fuhrman
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Blvd MSC 7238, Bethesda, MD 20892 7238, USA
Anticancer Res 33:543-51. 2013..We investigated six polymorphisms in CYP24A1 and two in the VDR gene in association with breast cancer risk... - Papillary thyroid cancer and polymorphic variants in TSHR- and RET-related genes: a nested case-control study within a cohort of U.S. radiologic technologistsStefan Lonn
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Room 7053, 6120 Executive Boulevard, Bethesda, MD 20892 7238, USA
Cancer Epidemiol Biomarkers Prev 16:174-7. 2007..7 (95% confidence interval, 1.1-11.8) for those who were homozygous (P(trend) = 0.001). Our data provide limited evidence that TSHR- and RET-related genes are related to papillary thyroid cancer risk... - The ATM missense mutation p.Ser49Cys (c.146C>G) and the risk of breast cancerDenise L Stredrick
Laboratory of Population Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 5060, USA
Hum Mutat 27:538-44. 2006..S49C, may be breast cancer susceptibility alleles. Because of their low frequency, even larger sample sizes are required to more firmly establish these associations... - Retrospective biodosimetry among United States radiologic technologistsParveen Bhatti
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
Radiat Res 167:727-34. 2007..S. radiologic technologists... - A pooled analysis of thyroid cancer incidence following radiotherapy for childhood cancerLene H S Veiga
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20892, USA
Radiat Res 178:365-76. 2012..Gender and number of treatments did not modify radiation effects. Thyroid cancer risks remained elevated many decades following radiotherapy, highlighting the need for continued follow up of childhood cancer survivors... - International study of factors affecting human chromosome translocationsAlice J Sigurdson
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
Mutat Res 652:112-21. 2008..Our data provide stable estimates of background TF by age, gender, race, and smoking status and suggest an acceleration of chromosome damage above age 60 and among those with a history of smoking cigarettes... - Candidate single nucleotide polymorphism selection using publicly available tools: a guide for epidemiologistsParveen Bhatti
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892-7238, USA
Am J Epidemiol 164:794-804. 2006..The authors show a "real world" application of some existing bioinformatics tools for use in large epidemiologic studies and genetic analyses. They also reviewed alternative approaches that provide related information... - Predictors of 2,4-dichlorophenoxyacetic acid exposure among herbicide applicatorsParveen Bhatti
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892 7238, USA
J Expo Sci Environ Epidemiol 20:160-8. 2010..As a large proportion of the variance remained unexplained, further studies should be conducted to try to systematically assess other exposure determinants... - Can low-dose radiation increase risk of cardiovascular disease?Parveen Bhatti
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Lancet 372:697-9. 2008 - Genetic variation and willingness to participate in epidemiologic research: data from three studiesParveen Bhatti
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, EPS 7091, MSC 7238, Bethesda, MD 20892 7238, USA
Cancer Epidemiol Biomarkers Prev 14:2449-53. 2005..To the extent possible, investigators should evaluate their own genetic data for bias in response categories...