Parveen Bhatti

Summary

Affiliation: Fred Hutchinson Cancer Research Center
Country: USA

Publications

  1. pmc Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumors
    Parveen Bhatti
    Department of Health ad Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 18:1841-8. 2009
  2. pmc Racial differences in the association between night shift work and melatonin levels among women
    Parveen Bhatti
    Public Health Scienes Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Am J Epidemiol 177:388-93. 2013
  3. pmc Nightshift work and risk of ovarian cancer
    Parveen Bhatti
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Occup Environ Med 70:231-7. 2013
  4. doi request reprint Invited commentary: Shift work and cancer
    Parveen Bhatti
    Program in Epidemiology, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Am J Epidemiol 176:760-3; discussion 764-5. 2012
  5. pmc Blood spots as an alternative to whole blood collection and the effect of a small monetary incentive to increase participation in genetic association studies
    Parveen Bhatti
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    BMC Med Res Methodol 9:76. 2009
  6. pmc Novel breast cancer risk alleles and interaction with ionizing radiation among U.S. radiologic technologists
    Parveen Bhatti
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Radiat Res 173:214-24. 2010
  7. pmc Diagnostic X-ray examinations and increased chromosome translocations: evidence from three studies
    Parveen Bhatti
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Radiat Environ Biophys 49:685-92. 2010
  8. pmc Comparison of occupational exposure assessment methods in a case-control study of lead, genetic susceptibility and risk of adult brain tumours
    Parveen Bhatti
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Occup Environ Med 68:4-9. 2011
  9. pmc Wood dust exposure and risk of lung cancer
    Parveen Bhatti
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Occup Environ Med 68:599-604. 2011
  10. pmc Risk of second primary thyroid cancer after radiotherapy for a childhood cancer in a large cohort study: an update from the childhood cancer survivor study
    Parveen Bhatti
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, UA
    Radiat Res 174:741-52. 2010

Detail Information

Publications37

  1. pmc Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumors
    Parveen Bhatti
    Department of Health ad Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 18:1841-8. 2009
    ..Although the results of this study provide some evidence that lead may cause glioblastoma multiforme and meningioma through mechanisms related to oxidative damage, the results must be confirmed in other populations...
  2. pmc Racial differences in the association between night shift work and melatonin levels among women
    Parveen Bhatti
    Public Health Scienes Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Am J Epidemiol 177:388-93. 2013
    ....
  3. pmc Nightshift work and risk of ovarian cancer
    Parveen Bhatti
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Occup Environ Med 70:231-7. 2013
    ..We evaluated the association between self-reported nightshift work, a known circadian disruptor, and ovarian cancer in a population-based case-control study...
  4. doi request reprint Invited commentary: Shift work and cancer
    Parveen Bhatti
    Program in Epidemiology, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Am J Epidemiol 176:760-3; discussion 764-5. 2012
    ....
  5. pmc Blood spots as an alternative to whole blood collection and the effect of a small monetary incentive to increase participation in genetic association studies
    Parveen Bhatti
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    BMC Med Res Methodol 9:76. 2009
    ..However, dried blood spot collection, which is also a convenient method, offers a means of collecting peripheral blood samples from which analytes in addition to DNA can be obtained...
  6. pmc Novel breast cancer risk alleles and interaction with ionizing radiation among U.S. radiologic technologists
    Parveen Bhatti
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Radiat Res 173:214-24. 2010
    ..Even though a complete understanding of the way(s) in which these variants may increase breast cancer risk remains elusive, this approach may yield clues for further investigation...
  7. pmc Diagnostic X-ray examinations and increased chromosome translocations: evidence from three studies
    Parveen Bhatti
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Radiat Environ Biophys 49:685-92. 2010
    ....
  8. pmc Comparison of occupational exposure assessment methods in a case-control study of lead, genetic susceptibility and risk of adult brain tumours
    Parveen Bhatti
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Occup Environ Med 68:4-9. 2011
    ....
  9. pmc Wood dust exposure and risk of lung cancer
    Parveen Bhatti
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Occup Environ Med 68:599-604. 2011
    ..We investigated whether a history of wood dust exposure through occupational and hobby-related activities was associated with increased lung cancer risk...
  10. pmc Risk of second primary thyroid cancer after radiotherapy for a childhood cancer in a large cohort study: an update from the childhood cancer survivor study
    Parveen Bhatti
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, UA
    Radiat Res 174:741-52. 2010
    ....
  11. pmc Polymorphisms in estrogen biosynthesis and metabolism-related genes, ionizing radiation exposure, and risk of breast cancer among US radiologic technologists
    Alice J Sigurdson
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Boulevard, EPS 7060, MSC 7238, Bethesda, MD, 20892 7238, USA
    Breast Cancer Res Treat 118:177-84. 2009
    ..06). We found suggestive evidence that common variants in selected estrogen metabolizing genes may modify the association between ionizing radiation exposure and breast cancer risk...
  12. ncbi request reprint Polymorphisms in apoptosis- and proliferation-related genes, ionizing radiation exposure, and risk of breast cancer among U.S. Radiologic Technologists
    Alice J Sigurdson
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, EPS 7092, MSC 7238, Bethesda, MD 20892 7238, USA
    Cancer Epidemiol Biomarkers Prev 16:2000-7. 2007
    ..For this reason, potential modification of the relationship between ionizing radiation exposure and breast cancer risk by polymorphic apoptosis gene variants have not been investigated among radiation-exposed women...
  13. pmc Nucleotide excision repair polymorphisms may modify ionizing radiation-related breast cancer risk in US radiologic technologists
    Preetha Rajaraman
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892, USA
    Int J Cancer 123:2713-6. 2008
    ..1-21.3; EOR/Gy(AC/CC) = 0.6, 95% CI = <0, 4.6; p(het) = 0.01). These results suggest that common variants in nucleotide excision repair genes may modify the association between occupational radiation exposure and breast cancer risk...
  14. pmc Breast cancer risk polymorphisms and interaction with ionizing radiation among U.S. radiologic technologists
    Parveen Bhatti
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, MD 20892 7238, USA
    Cancer Epidemiol Biomarkers Prev 17:2007-11. 2008
    ..001). H19 is a maternally expressed imprinted mRNA that is closely involved in regulating the IGF2 gene and could exert its influence by this or by some other radiation-related pathway...
  15. pmc Routine diagnostic X-ray examinations and increased frequency of chromosome translocations among U.S. radiologic technologists
    Alice J Sigurdson
    Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, Radiation Epidemiology Branch, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Cancer Res 68:8825-31. 2008
    ..The slope estimate was consistent with expectation based on cytogenetic experience and atomic bomb survivor data...
  16. pmc Polymorphisms in oxidative stress and inflammation pathway genes, low-dose ionizing radiation, and the risk of breast cancer among US radiologic technologists
    Sara J Schonfeld
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, 6120 Executive Blvd MSC 7238, Bethesda, MD 20892, USA
    Cancer Causes Control 21:1857-66. 2010
    ..Polymorphic variation in oxidative stress and inflammatory-mediated pathway genes may modify radiation-related breast cancer risk...
  17. pmc Increased frequency of chromosome translocations associated with diagnostic x-ray examinations
    Parveen Bhatti
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Radiat Res 170:149-55. 2008
    ..002 to 0.013; P = 0.01). Chromosome damage has been linked with elevated cancer risk, and we found that cumulative radiation exposure from medical X-ray examinations was associated with increased numbers of chromosome translocations...
  18. pmc Chemotherapy and thyroid cancer risk: a report from the childhood cancer survivor study
    Lene H S Veiga
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard EPS 7051, MSC 7238, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 21:92-101. 2012
    ..We evaluated the chemotherapy-related risk of thyroid cancer in childhood cancer survivors and the possible joint effects of chemotherapy and radiotherapy...
  19. ncbi request reprint Polymorphisms in DNA repair genes, ionizing radiation exposure and risk of breast cancer in U.S. Radiologic technologists
    Parveen Bhatti
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892 7238, USA
    Int J Cancer 122:177-82. 2008
    ..The suggestive evidence found for modification of radiation-related breast cancer risk for 5 of the 55 SNPs evaluated requires confirmation in larger studies of women with quantified radiation breast doses in the low-to-moderate range...
  20. pmc Absolute risk prediction of second primary thyroid cancer among 5-year survivors of childhood cancer
    Stephanie A Kovalchik
    National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
    J Clin Oncol 31:119-27. 2013
    ..We developed three absolute risk models for second primary thyroid cancer to assist with long-term clinical monitoring of childhood cancer survivors...
  21. pmc Thyroid nodules, polymorphic variants in DNA repair and RET-related genes, and interaction with ionizing radiation exposure from nuclear tests in Kazakhstan
    Alice J Sigurdson
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892 7238, USA
    Radiat Res 171:77-88. 2009
    ..Other pathways such as genes in double-strand break repair, apoptosis and genes related to proliferation should also be pursued...
  22. pmc A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1)
    Gilles Thomas
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Nat Genet 41:579-84. 2009
    ..1 (rs999737; P = 1.74 x 10(-7)) localizes to RAD51L1, a gene in the homologous recombination DNA repair pathway. We also confirmed associations with loci on chromosomes 2q35, 5p12, 5q11.2, 8q24, 10q26 and 16q12.1...
  23. doi request reprint The impact of chronotype on melatonin levels among shift workers
    Parveen Bhatti
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Occup Environ Med 71:195-200. 2014
    ..The authors analysed the impact of chronotype on previously reported differences in melatonin levels among healthcare workers that exclusively worked night or day shifts...
  24. pmc No evidence for differences in DNA damage assessed before and after a cancer diagnosis
    Parveen Bhatti
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892 7238, USA
    Cancer Epidemiol Biomarkers Prev 17:990-4. 2008
    ..More work is needed to characterize the effect of cancer diagnosis on other phenotypic assays...
  25. doi request reprint Night shift work and levels of 6-sulfatoxymelatonin and cortisol in men
    Dana K Mirick
    Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 A830, P O Box 19024, Seattle, WA 98109, USA
    Cancer Epidemiol Biomarkers Prev 22:1079-87. 2013
    ..Night shift work is associated with cancer among men, but the biologic mechanism is unclear. We investigated whether male night shift workers showed changes in levels of melatonin and cortisol, potential biomarkers of cancer risk...
  26. pmc Sunlight, polymorphisms of vitamin D-related genes and risk of breast cancer
    Barbara J Fuhrman
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Blvd MSC 7238, Bethesda, MD 20892 7238, USA
    Anticancer Res 33:543-51. 2013
    ..We investigated six polymorphisms in CYP24A1 and two in the VDR gene in association with breast cancer risk...
  27. ncbi request reprint Papillary thyroid cancer and polymorphic variants in TSHR- and RET-related genes: a nested case-control study within a cohort of U.S. radiologic technologists
    Stefan Lonn
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Room 7053, 6120 Executive Boulevard, Bethesda, MD 20892 7238, USA
    Cancer Epidemiol Biomarkers Prev 16:174-7. 2007
    ..7 (95% confidence interval, 1.1-11.8) for those who were homozygous (P(trend) = 0.001). Our data provide limited evidence that TSHR- and RET-related genes are related to papillary thyroid cancer risk...
  28. ncbi request reprint Retrospective biodosimetry among United States radiologic technologists
    Parveen Bhatti
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
    Radiat Res 167:727-34. 2007
    ..S. radiologic technologists...
  29. pmc The ATM missense mutation p.Ser49Cys (c.146C>G) and the risk of breast cancer
    Denise L Stredrick
    Laboratory of Population Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 5060, USA
    Hum Mutat 27:538-44. 2006
    ..S49C, may be breast cancer susceptibility alleles. Because of their low frequency, even larger sample sizes are required to more firmly establish these associations...
  30. pmc A pooled analysis of thyroid cancer incidence following radiotherapy for childhood cancer
    Lene H S Veiga
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20892, USA
    Radiat Res 178:365-76. 2012
    ..Gender and number of treatments did not modify radiation effects. Thyroid cancer risks remained elevated many decades following radiotherapy, highlighting the need for continued follow up of childhood cancer survivors...
  31. ncbi request reprint Association of chromosome translocation rate with low dose occupational radiation exposures in u.s. Radiologic technologists
    Mark P Little
    a Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892
    Radiat Res 182:1-17. 2014
    ..However, there are substantial uncertainties in both occupational and other (personal-diagnostic-medical) doses that may be imperfectly taken into account in our analysis. ..
  32. pmc International study of factors affecting human chromosome translocations
    Alice J Sigurdson
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
    Mutat Res 652:112-21. 2008
    ..Our data provide stable estimates of background TF by age, gender, race, and smoking status and suggest an acceleration of chromosome damage above age 60 and among those with a history of smoking cigarettes...
  33. ncbi request reprint Candidate single nucleotide polymorphism selection using publicly available tools: a guide for epidemiologists
    Parveen Bhatti
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 7238, USA
    Am J Epidemiol 164:794-804. 2006
    ..The authors show a "real world" application of some existing bioinformatics tools for use in large epidemiologic studies and genetic analyses. They also reviewed alternative approaches that provide related information...
  34. pmc Predictors of 2,4-dichlorophenoxyacetic acid exposure among herbicide applicators
    Parveen Bhatti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892 7238, USA
    J Expo Sci Environ Epidemiol 20:160-8. 2010
    ..As a large proportion of the variance remained unexplained, further studies should be conducted to try to systematically assess other exposure determinants...
  35. ncbi request reprint Can low-dose radiation increase risk of cardiovascular disease?
    Parveen Bhatti
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Lancet 372:697-9. 2008
  36. pmc Calibrating a population-based job-exposure matrix using inspection measurements to estimate historical occupational exposure to lead for a population-based cohort in Shanghai, China
    Dong Hee Koh
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, North Bethesda, Maryland, USA
    J Expo Sci Environ Epidemiol 24:9-16. 2014
    ..The most common lead-exposed jobs were manufacturing electronic equipment. These historical lead estimates should enhance our ability to detect associations between lead exposure and cancer risk in the future epidemiologic analyses. ..
  37. ncbi request reprint Genetic variation and willingness to participate in epidemiologic research: data from three studies
    Parveen Bhatti
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, EPS 7091, MSC 7238, Bethesda, MD 20892 7238, USA
    Cancer Epidemiol Biomarkers Prev 14:2449-53. 2005
    ..To the extent possible, investigators should evaluate their own genetic data for bias in response categories...