- Beta-globin gene switching and DNase I sensitivity of the endogenous beta-globin locus in mice do not require the locus control regionM A Bender
Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
Mol Cell 5:387-93. 2000....
- Flanking HS-62.5 and 3' HS1, and regions upstream of the LCR, are not required for beta-globin transcriptionM A Bender
Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Blood 108:1395-401. 2006..We demonstrate deletion of these regions alone, and in combination, do not affect transcription, bringing into question current models for the regulation of the beta-globin locus...