William E Barlow

..Interpretive performance of screening mammography varies substantially by facility, but performance of diagnostic interpretation has not been studied...

..Radiologists differ in their ability to interpret screening mammograms accurately. We investigated the relationship of radiologist characteristics to actual performance from 1996 to 2001...

..We used prospective risk information to predict a diagnosis of breast cancer in a cohort of 1 million women undergoing screening mammography...

..Methods to estimate the direct medical costs of cancer care have evolved into several commonly used methods...

..Serial positron emission tomography (PET) has been shown to predict pathologic response in this setting. We evaluated serial quantitative PET tumor blood flow (BF) and metabolism as in vivo measurements to predict patient outcome...

..To assess the relationship between radiologists' perception of and experience with medical malpractice and their patient-recall rates in actual community-based clinical settings...

..All patients had subsequent weekly paclitaxel for 12 weeks before surgery...

..The efficacy of breast cancer screening in the community may differ from that suggested by the results of randomized trials, and no data have been available on efficacy among women who have different levels of breast cancer risk...

..This study does not provide any evidence in support of changing surveillance intervals for different subgroups...

..However, only age was statistically significant. No association was found between radiologists' risk estimate and their recall rate. CONCLUSION: U.S. radiologists have a heightened perception of breast cancer risk...

..Obesity is increasing among American women, especially as they age. The influence of obesity on the accuracy of screening mammography has not been studied extensively...

..However, relationships between these factors and risk of molecularly-defined subtypes of breast cancer have not been established...

..Preplanned secondary analysis of data from participants receiving acupuncture in a randomized clinical trial...

..This project had two purposes: to develop a methodology to estimate dental care utilization using claims data and to use this methodology to compare utilization of dental care between adults with and without diabetes...

..Having a first-degree family history of breast cancer was associated with an increased risk of triple-negative breast cancer with a magnitude of association similar to that for the predominant ER+ subtype and ER-/PR-/HER2+ breast cancer...

..As part of a large trial evaluating acupuncture for chronic low back pain, we sought to identify subgroups of participants that were particularly responsive to acupuncture...

..Adolescents, who are still gaining bone, may be particularly affected, but there has been little study of the association in adolescent users and none following discontinuation...

..Breast augmentation is not associated with an increased risk of breast cancer; however, implants may interfere with the detection of breast cancer thereby delaying cancer diagnosis in women with augmentation...

..To examine time trends in radiologists' interpretive performance at screening mammography between 1996 and 2004...

..06). This study did not find a strong association between DMPA use and bone density. Further prospective evaluation of bone density changes with DMPA use and after DMPA discontinuation are needed in this age group...

..We evaluated whether age, breast density, self-reported breast lump, and previous mammography influence the performance of diagnostic mammography...

..However, despite high national mammography screening rates, late-stage breast cancers still occur, possibly because of failures in screening implementation...

..No additional benefit could be ascribed to prenatal institution of services. A combination of universal and risk-based support for new parents is recommended, rather than the provision of risk-based services alone...

..31-2.56). Neither parity nor age at first birth was associated with triple-negative breast cancer. In contrast to ER+ and ER-/PR-/HER2+ subtypes, reproductive history does not appear to be a risk factor for triple-negative breast cancer...

..An alternative is using administrative health-care data to identify second breast cancer events; however, these algorithms must be validated against a gold standard...

..All p-values for between-group differences were >0.55. In conclusion, within the limitations of this study, OCs did not appear to impact bone density over time in this cohort of reproductive-age women...

..Medical expenditures adjusted for price differences are a barometer of total resources devoted to patient care and thus may reflect treatment differentials...

..Our objectives were to describe the prevalence of periodontal care (a marker of periodontitis) among persons with and without diabetes and to examine the association between periodontal care and diabetes...

..To examine how frequently Breast Imaging Reporting and Data System (BI-RADS) mammographic screening assessments were associated with expected clinical management recommendations...

..We compared associations between several factors and risk of ductal, lobular, and mixed ductal-lobular breast cancers...

..In a large population of older adults, we assessed the effectiveness of the pneumococcal vaccine...

..The objective of this study was to assess the value of research of the RxPONDER study, an ongoing comparative effectiveness RCT designed to evaluate a 21-gene profile in early stage, node-positive breast cancer...

..Additionally, a masking study with a subsample of subjects may be a feasible and cost-effective alternative to the time- and cost-intensive methodological approach of masking all medical records...

..Given the association between MIBI uptake and tumor blood flow, this prognostic capability may be related to retained tumor vascularity after treatment...

..We studied these markers in a clinical trial setting with patients with breast cancer treated by a uniform drug regimen so that treatment was not associated with variability in outcome...

..The ordinal regression method is the standard approach used when evaluating tests with ordinal values. The direct ROC modeling method is a more recently developed approach, motivated by applications to tests with continuous values...

..To assess the impact of Guide to Decide (GtD), a web-based, personally-tailored decision aid designed to inform women's decisions about prophylactic tamoxifen and raloxifene use...

..Depot medroxyprogesterone acetate (DMPA) injectable contraception may decrease bone density and increase the risk for osteoporosis in later life. Prospective data are scarce, especially of the effects of DMPA discontinuation on bone...

..Participating families received more services and a greater variety of services than families in usual care. Whether these differences result in beneficial outcomes for families or the health plan are topics of the subsequent papers...

..Exercise training for patients with Alzheimer disease combined with teaching caregivers how to manage behavioral problems may help decrease the frailty and behavioral impairment that are often prevalent in patients with Alzheimer disease...

..This trial addresses the importance of needle placement and skin penetration in eliciting acupuncture effects for patients with chronic low back pain...

..Compare GHb among people with diabetes who have and have not received periodontal care...

..Individual trials have had limited power to show overall benefit or benefits within subsets...