Lu Wang

Summary

Affiliation: Fox Chase Cancer Center
Country: USA

Publications

  1. doi request reprint Target repositional accuracy and PTV margin verification using three-dimensional cone-beam computed tomography (CBCT) in stereotactic body radiotherapy (SBRT) of lung cancers
    Lu Wang
    Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    J Appl Clin Med Phys 13:3708. 2012
  2. ncbi request reprint Benefit of three-dimensional image-guided stereotactic localization in the hypofractionated treatment of lung cancer
    Lu Wang
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Int J Radiat Oncol Biol Phys 66:738-47. 2006
  3. doi request reprint Dosimetric comparison of stereotactic body radiotherapy using 4D CT and multiphase CT images for treatment planning of lung cancer: evaluation of the impact on daily dose coverage
    Lu Wang
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Radiother Oncol 91:314-24. 2009
  4. ncbi request reprint Commissioning and quality assurance of a commercial stereotactic treatment-planning system for extracranial IMRT
    Lu Wang
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    J Appl Clin Med Phys 7:21-34. 2006
  5. ncbi request reprint Stereotactic IMRT for prostate cancer: setup accuracy of a new stereotactic body localization system
    Lu Wang
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    J Appl Clin Med Phys 5:18-28. 2004
  6. doi request reprint Rectal dose variation during the course of image-guided radiation therapy of prostate cancer
    Lili Chen
    Radiation Oncology Department, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Radiother Oncol 95:198-202. 2010
  7. ncbi request reprint Magnetic resonance-based treatment planning for prostate intensity-modulated radiotherapy: creation of digitally reconstructed radiographs
    Lili Chen
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Int J Radiat Oncol Biol Phys 68:903-11. 2007
  8. ncbi request reprint Comparing computed tomography localization with daily ultrasound during image-guided radiation therapy for the treatment of prostate cancer: a prospective evaluation
    Steven J Feigenberg
    Fox Chase Cancer Center, Department of Radiation Oncology, Philadelphia, Pennsylvania 19111, USA
    J Appl Clin Med Phys 8:2268. 2007
  9. ncbi request reprint Dosimetric advantage and clinical implication of a micro-multileaf collimator in the treatment of prostate with intensity-modulated radiotherapy
    Lu Wang
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Med Dosim 30:97-103. 2005
  10. doi request reprint The dosimetric impact of dental implants on head-and-neck volumetric modulated arc therapy
    Mu Han Lin
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
    Phys Med Biol 58:1027-40. 2013

Collaborators

Detail Information

Publications41

  1. doi request reprint Target repositional accuracy and PTV margin verification using three-dimensional cone-beam computed tomography (CBCT) in stereotactic body radiotherapy (SBRT) of lung cancers
    Lu Wang
    Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    J Appl Clin Med Phys 13:3708. 2012
    ..This demonstrated that the PTV margin that is designed on the MIP image-based ITV was adequate for lung SBRT...
  2. ncbi request reprint Benefit of three-dimensional image-guided stereotactic localization in the hypofractionated treatment of lung cancer
    Lu Wang
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Int J Radiat Oncol Biol Phys 66:738-47. 2006
    ..The aim of this study was to investigate the benefit of image-guided stereotactic localization in the hypofractionated treatment for medically inoperable non-small-cell lung cancer...
  3. doi request reprint Dosimetric comparison of stereotactic body radiotherapy using 4D CT and multiphase CT images for treatment planning of lung cancer: evaluation of the impact on daily dose coverage
    Lu Wang
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Radiother Oncol 91:314-24. 2009
    ..To investigate the dosimetric impact of using 4D CT and multiphase (helical) CT images for treatment planning target definition and the daily target coverage in hypofractionated stereotactic body radiotherapy (SBRT) of lung cancer...
  4. ncbi request reprint Commissioning and quality assurance of a commercial stereotactic treatment-planning system for extracranial IMRT
    Lu Wang
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    J Appl Clin Med Phys 7:21-34. 2006
    ..However, the plans calculated by both methods met our clinical criteria. We conclude that the accuracy of the XKnifetrade mark RT2 treatment-planning system is adequate for the clinical implementation of stereotactic IMRT...
  5. ncbi request reprint Stereotactic IMRT for prostate cancer: setup accuracy of a new stereotactic body localization system
    Lu Wang
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    J Appl Clin Med Phys 5:18-28. 2004
    ..A rigid frame system serves as a reliable alignment reference in terms of repositioning patients into the planning position, while skin-based reference showed larger deviations in repositioning patients...
  6. doi request reprint Rectal dose variation during the course of image-guided radiation therapy of prostate cancer
    Lili Chen
    Radiation Oncology Department, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Radiother Oncol 95:198-202. 2010
    ..To investigate the change in rectal dose during the treatment course for intensity-modulated radiotherapy (IMRT) of prostate cancer with image-guidance...
  7. ncbi request reprint Magnetic resonance-based treatment planning for prostate intensity-modulated radiotherapy: creation of digitally reconstructed radiographs
    Lili Chen
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Int J Radiat Oncol Biol Phys 68:903-11. 2007
    ....
  8. ncbi request reprint Comparing computed tomography localization with daily ultrasound during image-guided radiation therapy for the treatment of prostate cancer: a prospective evaluation
    Steven J Feigenberg
    Fox Chase Cancer Center, Department of Radiation Oncology, Philadelphia, Pennsylvania 19111, USA
    J Appl Clin Med Phys 8:2268. 2007
    ..The isocenter shifts generated by using a CT unit in the treatment room correlate highly with shifts produced by the BAT Ultrasound system...
  9. ncbi request reprint Dosimetric advantage and clinical implication of a micro-multileaf collimator in the treatment of prostate with intensity-modulated radiotherapy
    Lu Wang
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Med Dosim 30:97-103. 2005
    ..When used for conventional fractionation scheme, mMLC for IMRT of the prostate may reduce the toxicity to the critical organs...
  10. doi request reprint The dosimetric impact of dental implants on head-and-neck volumetric modulated arc therapy
    Mu Han Lin
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
    Phys Med Biol 58:1027-40. 2013
    ..We demonstrated that it was effective to use the material's electron-density ratio to account for the dosimetric impact of the dental implant...
  11. doi request reprint Measurement comparison and Monte Carlo analysis for volumetric-modulated arc therapy (VMAT) delivery verification using the ArcCHECK dosimetry system
    Mu Han Lin
    Fox Chase Cancer Center, Philadelphia, PA, USA
    J Appl Clin Med Phys 14:3929. 2013
    ....
  12. ncbi request reprint Effect of collimator and couch angle change on breast IMRT dose distributions
    Jie Yang
    Department of Radiation Oncology, Penn State Cancer Institute, Hershey, PA 17033, USA
    J Appl Clin Med Phys 10:3058. 2009
    ..Our results show that a 4-degree change in the collimator angle or the couch angle did not affect the dose distribution significantly and it is acceptable in the clinic for patient treatment...
  13. doi request reprint 4D patient dose reconstruction using online measured EPID cine images for lung SBRT treatment validation
    Mu Han Lin
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Med Phys 39:5949-58. 2012
    ..This study aims to develop an EPID-guided 4D patient dose reconstruction framework and to investigate its feasibility for lung SBRT treatment validation...
  14. ncbi request reprint MRI-based treatment planning for radiotherapy: dosimetric verification for prostate IMRT
    Lili Chen
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
    Int J Radiat Oncol Biol Phys 60:636-47. 2004
    ..Furthermore, it will reduce treatment cost by avoiding redundant CT scans and save patient, staff, and machine time. The purpose of this study is to investigate the dosimetric accuracy of MRI-based treatment planning for prostate IMRT...
  15. ncbi request reprint Intensity modulated radiation therapy (IMRT) decreases acute skin toxicity for women receiving radiation for breast cancer
    Gary M Freedman
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Am J Clin Oncol 29:66-70. 2006
    ..Our hypothesis is that measures to decrease dose inhomogeneity within the breast and skin with IMRT will improve acute skin toxicity...
  16. doi request reprint Evaluation of the cone beam CT for internal target volume localization in lung stereotactic radiotherapy in comparison with 4D MIP images
    Lu Wang
    Department of Radiation Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, Pennsylvania 19111
    Med Phys 40:111709. 2013
    ..The authors' results suggest that CBCT and MIP images are equivalent in determining an ITV's position in the conditions studied. The CBCT is adequate in providing imaging-guidance for lung cancer treatment. ..
  17. doi request reprint Determination of grade and subtype of meningiomas by using histogram analysis of diffusion-tensor imaging metrics
    Sumei Wang
    Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St, 219 Dulles Bldg, Philadelphia, PA 19104, USA
    Radiology 262:584-92. 2012
    ..To determine whether histogram analysis of diffusion-tensor (DT) magnetic resonance (MR) imaging metrics, including tensor shape measurements, can help determine the grades and subtypes of meningiomas...
  18. doi request reprint Propensity score-based comparison of long-term outcomes with 3-dimensional conformal radiotherapy vs intensity-modulated radiotherapy for esophageal cancer
    Steven H Lin
    Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Int J Radiat Oncol Biol Phys 84:1078-85. 2012
    ..We hypothesized that the dosimetric advantages of IMRT should translate to substantive benefits in clinical outcomes compared with 3D-CRT...
  19. ncbi request reprint Dosimetric advantage of using 6 MV over 15 MV photons in conformal therapy of lung cancer: Monte Carlo studies in patient geometries
    Lu Wang
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Appl Clin Med Phys 3:51-9. 2002
    ..Any gains in radial dose uniformity across steep density gradients for higher energy beams must be weighed carefully against the lateral beam degradation due to penumbra widening...
  20. ncbi request reprint Monte Carlo evaluation of 6 MV intensity modulated radiotherapy plans for head and neck and lung treatments
    Lu Wang
    Med Phys 29:2705-17. 2002
    ..Critical normal tissue DVHs (cord, lung, brainstem) are changed by <10% at the high dose end and mean lung doses are changed by <6%...
  21. doi request reprint Silhouette smoothing for real-time rendering of mesh surfaces
    Lu Wang
    School of Computer Science and Technology, Shandong University, Jinan, PR China
    IEEE Trans Vis Comput Graph 14:640-52. 2008
    ..We speed up computation with GPU assistance to achieve real-time rendering of coarse meshes with the smoothed silhouettes. Experiments show that this method outperforms previous methods for silhouette smoothing...
  22. ncbi request reprint Evaluation of deep inspiration breath-hold lung treatment plans with Monte Carlo dose calculation
    Ellen D Yorke
    Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Int J Radiat Oncol Biol Phys 53:1058-70. 2002
    ..To evaluate dosimetry of deep inspiration breath-hold (DIBH) relative to free breathing (FB) for three-dimensional conformal radiation therapy of lung cancer with 6-MV photons and Monte Carlo (MC) dose calculations...
  23. ncbi request reprint [Effect of sodium arsenite on the proliferation and cell cycle of keratogenetic cells]
    Xian Ce Sun
    Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 22:219-20. 2004
  24. ncbi request reprint [Study on the inhibitory effect of small tripeptide CMS024 on tumor growth and metastasis in nude mice model of human hepatocellular carcinoma metastasis]
    Yan Li
    Liver Cancer Institute and Zhongshan Hospital of Fudan University, Shanghai 200032, China
    Zhonghua Yi Xue Za Zhi 84:675-9. 2004
    ..This experiment was designed to study the effect of small molecule tripeptide CMS024 on tumor growth and metastasis in a nude mice model of human hepatocellular carcinoma (HCC) metastasis...
  25. ncbi request reprint Mechanical strain inhibits airway smooth muscle gene transcription via protein kinase C signaling
    Lu Wang
    Department of Psysiology, University of Manitoba, Winnipeg, Canada
    Am J Respir Cell Mol Biol 31:54-61. 2004
    ..These data suggest a previously unknown role for PKC isoforms in mechanosensitive signaling in airway myocytes that is associated with coordinated regulation of actin cytoskeletal dynamics and smooth muscle-specific gene transcription...
  26. ncbi request reprint Analysis of Common Deletion (CD) and a novel deletion of mitochondrial DNA induced by ionizing radiation
    Lu Wang
    Department of Pathology, Institute of Development, Aging and Cancer, Tohoku University, Seiryo machi, Sendai, Japan
    Int J Radiat Biol 83:433-42. 2007
    ..In order to identify supportive evidence of radiation exposure to cells, we analyzed the relationship between exposure to ionizing radiation and the induction of deletions in mitochondrial DNA (mtDNA)...
  27. ncbi request reprint Fibrin fragment D-dimer and the risk of future venous thrombosis
    Mary Cushman
    Laboratory for Clinical Biochemistry Research and Department of Medicine, University of Vermont, Colchester, VT 05446, USA
    Blood 101:1243-8. 2003
    ..D-dimer is strongly and positively related to the occurrence of future venous thrombosis...
  28. ncbi request reprint Protein C, antithrombin, and venous thromboembolism incidence: a prospective population-based study
    Aaron R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1015, USA
    Arterioscler Thromb Vasc Biol 22:1018-22. 2002
    ..Attributable risk estimates suggest that low protein C levels account for approximately 2.5% of venous thromboembolic events in the ARIC population...
  29. pmc High-throughput genotyping of single nucleotide polymorphisms using new biplex invader technology
    Michael Olivier
    Stanford Human Genome Center, Stanford University School of Medicine, 975 California Avenue, Palo Alto, CA 94305, USA
    Nucleic Acids Res 30:e53. 2002
    ..The biplex invader assay with its automated set-up and analysis offers a new efficient high-throughput genotyping platform that is suitable for association studies in large study cohorts...
  30. pmc Coronary artery calcification and myocardial perfusion in asymptomatic adults: the MESA (Multi-Ethnic Study of Atherosclerosis)
    Lu Wang
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA
    J Am Coll Cardiol 48:1018-26. 2006
    ..This study assessed the cross-sectional association between coronary artery calcification (CAC) and myocardial perfusion in an asymptomatic population...
  31. pmc Length oscillation induces force potentiation in infant guinea pig airway smooth muscle
    Lu Wang
    Dept of Pediatrics, Duke University Medical Center, Rm 302, Bell Bldg, Box 2994, Durham, NC 27710, USA
    Am J Physiol Lung Cell Mol Physiol 289:L909-15. 2005
    ..Our results suggest a potentiated mechanosensitive contractile property of hyperresponsive airway smooth muscle. This can account for further bronchoconstriction triggered by deep inspiration in hyperresponsive airways...
  32. doi request reprint Telemedical diagnosis of retinopathy of prematurity intraphysician agreement between ophthalmoscopic examination and image-based interpretation
    Karen E Scott
    Department of Ophthalmology, Division of Neonatology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Ophthalmology 115:1222-1228.e3. 2008
    ..To evaluate the intraphysician agreement between ophthalmoscopic examination and image-based telemedical interpretation for retinopathy of prematurity (ROP) diagnosis, when performed by the same expert physician grader...
  33. ncbi request reprint The prognostic significance of preoperative plasma levels of osteopontin in patients with hepatocellular carcinoma
    Hui Zhang
    Liver Cancer Institute and Zhongshan Hospital, Institutes of Biomedical Science, Fudan University, 180 Feng Lin Road, Shanghai, 200032, China
    J Cancer Res Clin Oncol 132:709-17. 2006
    ..This suggests that the preoperative plasma OPN level can be used as a predictive marker for HCC recurrence and may be helpful to assess the prognosis of patients with HCC after surgery...
  34. ncbi request reprint A maturational model for the study of airway smooth muscle adaptation to mechanical oscillation
    Lu Wang
    Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA
    Can J Physiol Pharmacol 83:817-24. 2005
    ..It is important to study the maturational profile of ASM adaptation as it could contribute to juvenile hyperresponsiveness...
  35. pmc Receptor isoform and ligand-specific modulation of dihydrotestosterone-induced prostate specific antigen gene expression and prostate tumor cell growth by estrogens
    Yuan Shan Zhu
    Department of Medicine Endocrinology, Weill Medical College of Cornell University, 1300 York Ave, Box 149, New York, NY 10021, USA
    J Androl 26:500-8; discussion 509-10. 2005
    ....
  36. ncbi request reprint Modelling and control for heart rate regulation during treadmill exercise
    Steven W Su
    Biomed Syst Lab, New South Wales Univ, Sydney, NSW, Australia
    Conf Proc IEEE Eng Med Biol Soc 1:4299-302. 2006
    ..Both conventional proportional-integral-derivative (PID) control and the proposed approaches have been employed for the controller design. The proposed algorithm achieves much better heart rate tracking performance...
  37. ncbi request reprint Relationship between retinal arteriolar narrowing and myocardial perfusion: multi-ethnic study of atherosclerosis
    Lu Wang
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
    Hypertension 51:119-26. 2008
    ..This finding suggests that retinal arteriolar narrowing may serve as a marker of coronary microvascular disease...
  38. ncbi request reprint Telemedical retinopathy of prematurity diagnosis: accuracy, reliability, and image quality
    Michael F Chiang
    Department of Ophthalmology, Columbia University College of Physicians and Surgeons, 635 W 165th St, Box 92, New York, NY 10032, USA
    Arch Ophthalmol 125:1531-8. 2007
    ..To prospectively measure accuracy, reliability, and image quality of telemedical retinopathy of prematurity (ROP) diagnosis...
  39. ncbi request reprint Hepatocellular carcinoma with situs inversus totalis and polysplenia syndrome
    Tao Li
    Liver Int 27:1430-1. 2007
  40. pmc MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
    James Bean
    Human Oncology and Pathogenesis Program, Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 104:20932-7. 2007
    ..Taken together, these data suggest that MET amplification occurs independently of EGFR(T790M) mutations and that MET may be a clinically relevant therapeutic target for some patients with acquired resistance to gefitinib or erlotinib...
  41. pmc Retinopathy of prematurity management using single-image vs multiple-image telemedicine examinations
    Alexandra Lajoie
    Department of Ophthalmology, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Am J Ophthalmol 146:298-309. 2008
    ..To compare performance of single-image vs multiple-image telemedicine examinations for retinopathy of prematurity (ROP) diagnosis...