FABRICE J ROEGIERS

Summary

Affiliation: Fox Chase Cancer Center
Country: USA

Publications

  1. ncbi Asymmetric cell division
    Fabrice Roegiers
    Departments of Physiology and Biochemistry, Howard Hughes Medical Institute, University of California, San Francisco, 533 Parnassus Ave, San Francisco, California, 94122, USA
    Curr Opin Cell Biol 16:195-205. 2004
  2. ncbi Regulation of membrane localization of Sanpodo by lethal giant larvae and neuralized in asymmetrically dividing cells of Drosophila sensory organs
    Fabrice Roegiers
    Howard Hughes Medical Institute and Department of Physiology and Biochemistry, University of California San Francisco, San Francisco, CA 94143 0725, USA
    Mol Biol Cell 16:3480-7. 2005
  3. ncbi Frequent unanticipated alleles of lethal giant larvae in Drosophila second chromosome stocks
    Fabrice Roegiers
    Fox Chase Cancer Center, Institute for Cancer Research, Philadelphia, PA 19111, USA
    Genetics 182:407-10. 2009
  4. ncbi Lethal giant larvae acts together with numb in notch inhibition and cell fate specification in the Drosophila adult sensory organ precursor lineage
    Nicholas Justice
    Department of Physiology, Howard Hughes Medical Institute, University of California, San Francisco, 533 Parnassus Avenue, San Francisco, CA 94143 0725, USA
    Curr Biol 13:778-83. 2003
  5. ncbi Numb independently antagonizes Sanpodo membrane targeting and Notch signaling in Drosophila sensory organ precursor cells
    Xin Tong
    Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Mol Biol Cell 21:802-10. 2010
  6. ncbi Dcas supports cell polarization and cell-cell adhesion complexes in development
    Nadezhda Tikhmyanova
    Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 5:e12369. 2010
  7. ncbi The evolutionarily conserved TSC/Rheb pathway activates Notch in tuberous sclerosis complex and Drosophila external sensory organ development
    Magdalena Karbowniczek
    Institute for Cancer Research, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
    J Clin Invest 120:93-102. 2010
  8. ncbi Conversion of neurons and glia to external-cell fates in the external sensory organs of Drosophila hamlet mutants by a cousin-cousin cell-type respecification
    Adrian W Moore
    Howard Hughes Medical Institute, Department of Physiology, University of California at San Francisco, CA 94143, USA
    Genes Dev 18:623-8. 2004
  9. ncbi The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta
    Eric C Lai
    Department of Molecular and Cell Biology, Howard Hughes Medical Institute, 545 Life Sciences Addition, University of California at Berkeley, Berkeley, CA 94720 3200, USA
    Development 132:2319-32. 2005

Research Grants

  1. Endocytic Control of Notch-Mediated Cell Fate Decisions in Neurogenesis
    FABRICE J ROEGIERS; Fiscal Year: 2010

Collaborators

Detail Information

Publications9

  1. ncbi Asymmetric cell division
    Fabrice Roegiers
    Departments of Physiology and Biochemistry, Howard Hughes Medical Institute, University of California, San Francisco, 533 Parnassus Ave, San Francisco, California, 94122, USA
    Curr Opin Cell Biol 16:195-205. 2004
    ..In vertebrates, analysis of dividing neural progenitor cells by in vivo imaging has raised questions about the role of asymmetric cell divisions during neurogenesis...
  2. ncbi Regulation of membrane localization of Sanpodo by lethal giant larvae and neuralized in asymmetrically dividing cells of Drosophila sensory organs
    Fabrice Roegiers
    Howard Hughes Medical Institute and Department of Physiology and Biochemistry, University of California San Francisco, San Francisco, CA 94143 0725, USA
    Mol Biol Cell 16:3480-7. 2005
    ..This study identifies a hitherto unreported role for Lgl as a regulator of Sanpodo during asymmetric cell division in the adult PNS...
  3. ncbi Frequent unanticipated alleles of lethal giant larvae in Drosophila second chromosome stocks
    Fabrice Roegiers
    Fox Chase Cancer Center, Institute for Cancer Research, Philadelphia, PA 19111, USA
    Genetics 182:407-10. 2009
    ..Taken together, these results encourage the routine testing of second chromosome stocks for second-site alleles of lgl...
  4. ncbi Lethal giant larvae acts together with numb in notch inhibition and cell fate specification in the Drosophila adult sensory organ precursor lineage
    Nicholas Justice
    Department of Physiology, Howard Hughes Medical Institute, University of California, San Francisco, 533 Parnassus Avenue, San Francisco, CA 94143 0725, USA
    Curr Biol 13:778-83. 2003
    ..These findings uncover a previously unknown function of Lgl in the inhibition of Notch and reveal different modes of action by which Lgl can influence cell fate in the neuroblast and SOP lineages...
  5. ncbi Numb independently antagonizes Sanpodo membrane targeting and Notch signaling in Drosophila sensory organ precursor cells
    Xin Tong
    Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Mol Biol Cell 21:802-10. 2010
    ....
  6. ncbi Dcas supports cell polarization and cell-cell adhesion complexes in development
    Nadezhda Tikhmyanova
    Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 5:e12369. 2010
    ..These results support an important role for Cas proteins in cell-cell adhesion signaling in development...
  7. ncbi The evolutionarily conserved TSC/Rheb pathway activates Notch in tuberous sclerosis complex and Drosophila external sensory organ development
    Magdalena Karbowniczek
    Institute for Cancer Research, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
    J Clin Invest 120:93-102. 2010
    ....
  8. ncbi Conversion of neurons and glia to external-cell fates in the external sensory organs of Drosophila hamlet mutants by a cousin-cousin cell-type respecification
    Adrian W Moore
    Howard Hughes Medical Institute, Department of Physiology, University of California at San Francisco, CA 94143, USA
    Genes Dev 18:623-8. 2004
    ..The fate-determining signals NOTCH and PAX2 act at multiple stages of lineage elaboration and HAMLET acts to modulate their activity in a branch-specific manner...
  9. ncbi The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta
    Eric C Lai
    Department of Molecular and Cell Biology, Howard Hughes Medical Institute, 545 Life Sciences Addition, University of California at Berkeley, Berkeley, CA 94720 3200, USA
    Development 132:2319-32. 2005
    ..We conclude that ubiquitination of Delta and Serrate by Neuralized and D-mib is an obligate feature of DSL ligand activation throughout Drosophila development...

Research Grants3

  1. Endocytic Control of Notch-Mediated Cell Fate Decisions in Neurogenesis
    FABRICE J ROEGIERS; Fiscal Year: 2010
    ....