Sanda Remakus

Summary

Affiliation: Fox Chase Cancer Center
Country: USA

Publications

  1. doi request reprint Memory CD8⁺ T cell protection
    Sanda Remakus
    Immune Cell Development and Host Defense, The Research Institute of Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
    Adv Exp Med Biol 785:77-86. 2013
  2. pmc Memory CD8⁺ T cells can outsource IFN-γ production but not cytolytic killing for antiviral protection
    Sanda Remakus
    Immune Cell Development and Host Defense Program, Research Institute of the Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
    Cell Host Microbe 13:546-57. 2013
  3. pmc Crosstalk between the type 1 interferon and nuclear factor kappa B pathways confers resistance to a lethal virus infection
    Daniel Rubio
    Immune Cell Development and Host Defense Program, Research Institute of Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
    Cell Host Microbe 13:701-10. 2013
  4. pmc CD4+ T cell help is dispensable for protective CD8+ T cell memory against mousepox virus following vaccinia virus immunization
    Min Fang
    the Research Institute at Fox Chase Cancer Center, Immune Cell Development and Host Defense Program, Philadelphia, Pennsylvania, USA
    J Virol 89:776-83. 2015
  5. pmc Memory CD8+ T cells specific for a single immunodominant or subdominant determinant induced by peptide-dendritic cell immunization protect from an acute lethal viral disease
    Sanda Remakus
    Fox Chase Cancer Center, Immune Cell Development and Host Defense Program, Philadelphia, Pennsylvania, USA
    J Virol 86:9748-59. 2012
  6. pmc Gamma interferon and perforin control the strength, but not the hierarchy, of immunodominance of an antiviral CD8+ T cell response
    Sanda Remakus
    Fox Chase Cancer Center, Program in Immune Cell Development and Host Defense, 333 Cottman Avenue, Philadelphia, PA 19111, USA
    J Virol 85:12578-84. 2011

Collaborators

  • Antonio Alcami
  • Min Fang
  • Luis J Sigal
  • Daniel Rubio
  • Felicia Roscoe
  • Xueying Ma
  • Ren Huan Xu
  • Mary Ellen Truckenmiller
  • Roshan J Thapa
  • Christopher C Norbury
  • Siddharth Balachandran
  • Tracy E Krouse

Detail Information

Publications6

  1. doi request reprint Memory CD8⁺ T cell protection
    Sanda Remakus
    Immune Cell Development and Host Defense, The Research Institute of Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
    Adv Exp Med Biol 785:77-86. 2013
    ..Here we discuss essential antiviral effector functions and highlight how recall expansion of memory CD8⁺ T cells may affect the primary response...
  2. pmc Memory CD8⁺ T cells can outsource IFN-γ production but not cytolytic killing for antiviral protection
    Sanda Remakus
    Immune Cell Development and Host Defense Program, Research Institute of the Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
    Cell Host Microbe 13:546-57. 2013
    ..Thus, during lethal virus challenge, memory CD8(+) T cells are required for cytolytic killing of infected cells, but primary effectors can play important roles by producing IFN-γ...
  3. pmc Crosstalk between the type 1 interferon and nuclear factor kappa B pathways confers resistance to a lethal virus infection
    Daniel Rubio
    Immune Cell Development and Host Defense Program, Research Institute of Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
    Cell Host Microbe 13:701-10. 2013
    ..These findings may also explain why some pathogens target both pathways to cause disease...
  4. pmc CD4+ T cell help is dispensable for protective CD8+ T cell memory against mousepox virus following vaccinia virus immunization
    Min Fang
    the Research Institute at Fox Chase Cancer Center, Immune Cell Development and Host Defense Program, Philadelphia, Pennsylvania, USA
    J Virol 89:776-83. 2015
    ..Our results may partly explain why the VACV vaccine is so effective...
  5. pmc Memory CD8+ T cells specific for a single immunodominant or subdominant determinant induced by peptide-dendritic cell immunization protect from an acute lethal viral disease
    Sanda Remakus
    Fox Chase Cancer Center, Immune Cell Development and Host Defense Program, Philadelphia, Pennsylvania, USA
    J Virol 86:9748-59. 2012
    ..This suggests it is feasible to produce effective antiviral CD8(+) T cell vaccines using single CD8(+) T cell determinants and that NK cells are no longer essential when memory CD8(+) T cells are present...
  6. pmc Gamma interferon and perforin control the strength, but not the hierarchy, of immunodominance of an antiviral CD8+ T cell response
    Sanda Remakus
    Fox Chase Cancer Center, Program in Immune Cell Development and Host Defense, 333 Cottman Avenue, Philadelphia, PA 19111, USA
    J Virol 85:12578-84. 2011
    ..Thus, our work shows that CD8(+) T cell immunodominance during VACV infection is not affected by the effects of IFN-γ on the antigen presentation machinery...