Eric G Moss

Summary

Affiliation: Fox Chase Cancer Center
Country: USA

Publications

  1. ncbi Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites
    Eric G Moss
    Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, PA 19111, USA
    Dev Biol 258:432-42. 2003
  2. ncbi MicroRNAs: something new under the sun
    Eric G Moss
    Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Curr Biol 12:R688-90. 2002
  3. ncbi Silencing unhealthy alleles naturally
    Eric G Moss
    Cell and Developmental Biology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Trends Biotechnol 21:185-7. 2003
  4. ncbi Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation
    Kathy Seggerson
    Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, PA 19111, USA
    Dev Biol 243:215-25. 2002
  5. ncbi RNA repair: damage control
    Alfonso Bellacosa
    Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    Curr Biol 13:R482-4. 2003
  6. ncbi The C. elegans heterochronic gene lin-46 affects developmental timing at two larval stages and encodes a relative of the scaffolding protein gephyrin
    Anita S R Pepper
    Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Development 131:2049-59. 2004
  7. ncbi MicroRNAs: hidden in the genome
    Eric G Moss
    Cell and Developmental Biology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Curr Biol 12:R138-40. 2002
  8. ncbi Temporally regulated expression of Lin-28 in diverse tissues of the developing mouse
    Dong Hua Yang
    Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, PA 19111, USA
    Gene Expr Patterns 3:719-26. 2003
  9. ncbi Heterochronic genes and the nature of developmental time
    Eric G Moss
    Department of Molecular Biology, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey 08084, USA
    Curr Biol 17:R425-34. 2007
  10. pmc Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency
    Anna Polesskaya
    Centre National de la Recherche Scientifique CNRS FRE 2944, Institut Andre Lwoff, Villejuif F 94801, France
    Genes Dev 21:1125-38. 2007

Collaborators

Detail Information

Publications12

  1. ncbi Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites
    Eric G Moss
    Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, PA 19111, USA
    Dev Biol 258:432-42. 2003
    ..elegans lin-4 and let-7 microRNAs, suggesting that microRNA regulation is a conserved feature of the Lin-28 gene in diverse animals...
  2. ncbi MicroRNAs: something new under the sun
    Eric G Moss
    Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Curr Biol 12:R688-90. 2002
    ..Although the targets of these miRNAs are still not known, excellent candidates have been identified based on sequence similarity to the miRNAs...
  3. ncbi Silencing unhealthy alleles naturally
    Eric G Moss
    Cell and Developmental Biology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Trends Biotechnol 21:185-7. 2003
    ..Small RNA technology is both extremely versatile, because virtually any expressed gene can be inhibited, and effective, because it exploits natural cellular machinery that evolved to use small RNAs to regulate gene expression...
  4. ncbi Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation
    Kathy Seggerson
    Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, PA 19111, USA
    Dev Biol 243:215-25. 2002
    ..The role of lin-4 may be to initiate or potentiate the lin-4-independent circuit. We speculate that a parallel lin-4-independent regulatory mechanism regulates the expression of lin-14...
  5. ncbi RNA repair: damage control
    Alfonso Bellacosa
    Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    Curr Biol 13:R482-4. 2003
    ..RNA damage can induce apoptosis and may be exploited for anti-cancer chemotherapy. It is a surprise, however, to learn that cells may repair RNA damage, suggesting a far greater significance of RNA in genotoxic stress...
  6. ncbi The C. elegans heterochronic gene lin-46 affects developmental timing at two larval stages and encodes a relative of the scaffolding protein gephyrin
    Anita S R Pepper
    Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Development 131:2049-59. 2004
    ..Our findings suggest that the LIN-46 protein acts as a scaffold for a multiprotein assembly that controls developmental timing, and expand the known roles of gephyrin-related proteins to development...
  7. ncbi MicroRNAs: hidden in the genome
    Eric G Moss
    Cell and Developmental Biology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Curr Biol 12:R138-40. 2002
    ..Some of these microRNAs have been conserved through evolution, and many are expressed only at specific times or places. How they act is just beginning to be understood, but their importance to biology is likely to be great...
  8. ncbi Temporally regulated expression of Lin-28 in diverse tissues of the developing mouse
    Dong Hua Yang
    Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, PA 19111, USA
    Gene Expr Patterns 3:719-26. 2003
    ....
  9. ncbi Heterochronic genes and the nature of developmental time
    Eric G Moss
    Department of Molecular Biology, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey 08084, USA
    Curr Biol 17:R425-34. 2007
    ..Homologs of certain heterochronic genes of vertebrates show temporally regulated expression patterns, and may ultimately reveal timing mechanisms not previously known to exist...
  10. pmc Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency
    Anna Polesskaya
    Centre National de la Recherche Scientifique CNRS FRE 2944, Institut Andre Lwoff, Villejuif F 94801, France
    Genes Dev 21:1125-38. 2007
    ..Our results unravel novel mechanisms of translational regulation in skeletal muscle and suggest that Lin-28 performs the role of "translational enhancer" in embryonic and adult cells and tissues...
  11. ncbi Small-interfering RNAs in the radar of the interferon system
    Eric G Moss
    Nat Cell Biol 5:771-2. 2003
  12. ncbi Localization of the developmental timing regulator Lin28 to mRNP complexes, P-bodies and stress granules
    Erica Balzer
    Department of Molecular Biology, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey 08084, USA
    RNA Biol 4:16-25. 2007
    ..These studies are consistent with a model in which Lin28 binds mRNAs in the nucleus and accompanies them to ribosomes and P-bodies. We propose that Lin28 influences the translation or stability of specific mRNAs during differentiation...