Research Topics
| CHANG-MING C MASummaryAffiliation: Fox Chase Cancer Center Country: USA Publications
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Detail Information
Publications
A Monte Carlo dose calculation tool for radiotherapy treatment planningC M Ma
Radiation Oncology Department, Stanford University School of Medicine, CA 94305, USA
Phys Med Biol 47:1671-89. 2002..The effect of energy cut-offs for particle transport was investigated. Variance reduction techniques were implemented in MCDOSE to achieve a speedup factor of 10-30 compared to DOSXYZ...
A quality assurance phantom for IMRT dose verificationC M Ma
Radiation Oncology Department, Stanford University School of Medicine, Stanford, CA 94305, USA
Phys Med Biol 48:561-72. 2003..The QA phantom has been integrated as a routine QA procedure for the patient's IMRT dose verification at Stanford since 1999...
A comparative dosimetric study on tangential photon beams, intensity-modulated radiation therapy (IMRT) and modulated electron radiotherapy (MERT) for breast cancer treatmentC M Ma
Department of Radiation Oncology Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Phys Med Biol 48:909-24. 2003..It is concluded that MERT has superior capabilities to achieve dose conformity both laterally and in the depth direction, which will be well suited for treating superficial targets such as breast cancer...
Effect of statistical uncertainties on Monte Carlo treatment planningC M Ma
Radiation Oncology Department, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Phys Med Biol 50:891-907. 2005..We provide practical guidelines for the clinical implementation of Monte Carlo treatment planning and show realistic examples of Monte Carlo based IMRT and MERT plans...
Monitor unit calculation for Monte Carlo treatment planningC M Ma
Radiation Oncology Department, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Phys Med Biol 49:1671-87. 2004..It is also used for absolute dose calculations using Monte Carlo simulations for treatment verification, which has become part of our comprehensive IMRT quality assurance programme...
Shielding design for a laser-accelerated proton therapy systemJ Fan
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Phys Med Biol 52:3913-30. 2007..It is shown that the two-layer shielding design with 10-12 cm thick polyethylene and 4 cm thick lead can effectively absorb the unwanted particles to meet the shielding requirements...
A practical Monte Carlo MU verification tool for IMRT quality assuranceJ Fan
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Phys Med Biol 51:2503-15. 2006..The results between the point detector and MCSIM agreed to within 2%. A factor of 20 speedup can be achieved with the point detector method compared with direct Monte Carlo simulations...
Characterization of megavoltage electron beams delivered through a photon multi-leaf collimator (pMLC)F C P du Plessis
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Phys Med Biol 51:2113-29. 2006..Bremsstrahlung measurements taken at 60 cm SSD for a 9 x 9 cm2 field as shaped by the pMLC compared within 1% to bremsstrahlung measurements taken at 100 cm SSD for a 10 x 10 cm2 electron applicator field at 100 cm SSD...
Dosimetric evaluation of MRI-based treatment planning for prostate cancerL Chen
Radiation Oncology Department, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Phys Med Biol 49:5157-70. 2004..The difference in the target dose between CT- and MRI-based plans using homogeneous geometry was within 2.5%. Our results suggest that MRI-based treatment planning is suitable for radiotherapy of prostate cancer...
Impact of pelvic nodal irradiation with intensity-modulated radiotherapy on treatment of prostate cancerRobert A Price
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Int J Radiat Oncol Biol Phys 66:583-92. 2006..The aim of this study was to evaluate the feasibility of treating the pelvic lymphatic regions during prostate intensity-modulated radiotherapy (IMRT) with respect to our routine acceptance criteria...
Ultra-thin TLDs for skin dose determination in high energy photon beamsS Stathakis
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Phys Med Biol 51:3549-67. 2006..Knowing the dose received at the surface of the patient can lead to prediction of skin reactions helping with the design of new treatment techniques and alternative dose fractionation schemes...
Investigation of MR image distortion for radiotherapy treatment planning of prostate cancerZ Chen
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Phys Med Biol 51:1393-403. 2006..Using the point-by-point method, the geometrical distortion after the GDC were reduced to <3 mm for external contour determination and the effective FOV was expanded from 36 cm to 42 cm...
Elongated beamlets: a simple technique for segment and MU reduction for sMLC IMRT delivery on accelerators utilizing 5 mm leaf widthsR A Price
Department of Radiation Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
Phys Med Biol 50:N235-42. 2005..This technique directly translates to a decreased MSF(mod) allowing for decreased leakage dose to the patient, a decreased risk of exceeding secondary shielding limits in pre-existing vaults, and shorter treatment times...
Shielding evaluation for IMRT implementation in an existing accelerator vaultR A Price
Department of Radiation Oncology, Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, Pennsylvania 19111, USA
J Appl Clin Med Phys 4:231-8. 2003..6% when using the SMLC delivery technique and our measured modulation scaling factors. This compares with a previously published value of 1.6% for routine 3D CRT delivery on the Varian accelerator...
A particle track-repeating algorithm for proton beam dose calculationJ S Li
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Phys Med Biol 50:1001-10. 2005..The differences between them were within 2%. The new algorithm was about 13 times faster than the GEANT3 Monte Carlo code for a uniform phantom geometry and over 700 times faster for a heterogeneous phantom geometry...
Dosimetric verification of IMRT treatment planning using Monte Carlo simulations for prostate cancerJ Yang
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Phys Med Biol 50:869-78. 2005..These results suggest that heterogeneity correction should be used in dose calculation for prostate cancer with non-coplanar beam arrangements...
Effect of patient variation on standard- and hypo-fractionated radiotherapy of prostate cancerW Xiong
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Phys Med Biol 50:1483-92. 2005..On the other hand, for lower alpha/beta ratios, the beta term also plays a more important role in cell-killing and therefore the patient variation parameter sigmabeta must be considered when designing a new dose fractionation scheme...
Lens dose in MLC-based IMRT treatments of the head and neckTodd Pawlicki
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305 5487, USA
Int J Radiat Oncol Biol Phys 59:293-9. 2004....
Coulomb explosion effect and the maximum energy of protons accelerated by high-power lasersE Fourkal
Department of Radiation Physics, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
Phys Rev E Stat Nonlin Soft Matter Phys 71:036412. 2005..The heavy-ion motion is found to modify the longitudinal electric field distribution, thus changing the acceleration conditions for the protons...
Investigation of optimal beam margins for stereotactic radiotherapy of lung-cancer using Monte Carlo dose calculationsL Jin
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Phys Med Biol 52:3549-61. 2007..The impact of the number of beam angles on the relationship between V20 and the beam margin was assessed. Quantitative information about optimal beam margins for lung-cancer SBRT was obtained for clinical applications...
