Research Topics
| Andre KonskiSummaryAffiliation: Fox Chase Cancer Center Country: USA Publications
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Detail Information
Publications
Continuing evidence for poorer treatment outcomes for single male patients: retreatment data from RTOG 97-14Andre Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Int J Radiat Oncol Biol Phys 66:229-33. 2006..The specific aim of this study was to evaluate outcome differences by gender and partner status for patients treated on Radiation Therapy Oncology Group (RTOG) protocol 97-14...
Quality-adjusted survival analysis of Radiation Therapy Oncology Group (RTOG) 90-03: phase III randomized study comparing altered fractionation to standard fractionation radiotherapy for locally advanced head and neck squamous cell carcinomaAndre A Konski
Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA
Head Neck 31:207-12. 2009..To evaluate quality-adjusted survival (QAS) of patients with locally advanced squamous cell carcinoma of the head and neck treated with 4 different radiation fractionation schedules...
Feasibility of using administrative claims data for cost-effectiveness analysis of a clinical trialAndre Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
J Med Econ 11:611-23. 2008..This study was performed retrospectively to determine if Medicare claims data could be used to evaluate the cost effectiveness, from a payer perspective, of different radiation treatment schedules evaluated in a national clinical trial...
Long-term hormone therapy and radiation is cost-effective for patients with locally advanced prostate carcinomaAndre Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
Cancer 106:51-7. 2006..The specific objective of the current study was to determine whether LTAD was a cost-effective treatment for patients with locally advanced prostate carcinoma...
Disadvantage of men living alone participating in Radiation Therapy Oncology Group head and neck trialsAndre A Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
J Clin Oncol 24:4177-83. 2006..This study evaluated whether males without partners were disadvantaged for survival in Radiation Therapy Oncology Group (RTOG) head and neck cancer clinical trials...
Can molecular imaging predict response to preoperative chemoradiation in patients with rectal cancer? A Fox Chase Cancer Center prospective experienceAndre Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Semin Oncol 32:S63-7. 2005..Because response to preoperative treatment predicts clinical outcome, the utility of midtreatment PET scans to guide treatment decisions should be further explored in larger clinical studies...
Using decision analysis to determine the cost-effectiveness of intensity-modulated radiation therapy in the treatment of intermediate risk prostate cancerAndre Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Int J Radiat Oncol Biol Phys 66:408-15. 2006....
Does age matter in the selection of treatment for men with early-stage prostate cancer?Andre Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
Cancer 106:2598-602. 2006....
Correlation of molecular response as measured by 18-FDG positron emission tomography with outcome after chemoradiotherapy in patients with esophageal carcinomaAndre A Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Int J Radiat Oncol Biol Phys 69:358-63. 2007....
Evaluation of planned treatment breaks during radiation therapy for anal cancer: update of RTOG 92-08Andre Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Int J Radiat Oncol Biol Phys 72:114-8. 2008..Long-term efficacy and late toxicity reporting are the specific aims of this study...
Is proton beam therapy cost effective in the treatment of adenocarcinoma of the prostate?Andre Konski
Department of Radiation Oncology, Fox Chase Cancer Center, 333 Cottman Ave, Philadelphia, PA, USA
J Clin Oncol 25:3603-8. 2007..The specific aim of this study was to examine the cost effectiveness of proton beam radiation compared with current state-of-the art therapy in the treatment of patients with prostate cancer. Materials and..
Developing a radiation error scoring system to monitor quality control events in a radiation oncology departmentAndre Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
J Am Coll Radiol 6:45-50. 2009..The aims of this study were to evaluate the factors contributing to errors in the treatment of cancer patients undergoing radiation therapy and to develop a grading system that allows for the comparison of errors...
Use of molecular imaging to predict clinical outcome in patients with rectal cancer after preoperative chemotherapy and radiationAndre Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
Int J Radiat Oncol Biol Phys 74:55-9. 2009....
Economic analysis of radiation therapy oncology group 97-14: multiple versus single fraction radiation treatment of patients with bone metastasesAndre Konski
Department of Radiation Oncology, Wayne State University School of Medicine, Barbara Ann Karmanus Cancer Center, Detroit, MI 48201, USA
Am J Clin Oncol 32:423-8. 2009..The purpose of the analysis was to determine whether multiple fraction treatment is cost-effective in treating patients with bone metastasis, by preventing further retreatment...
Fluorouracil-based chemoradiation with either gemcitabine or fluorouracil chemotherapy after resection of pancreatic adenocarcinoma: 5-year analysis of the U.S. Intergroup/RTOG 9704 phase III trialWilliam F Regine
Department of Radiation Oncology, University of Maryland, Baltimore, MD, USA
Ann Surg Oncol 18:1319-26. 2011..The impact of the addition of gemcitabine to 5-fluorouracil (5-FU) chemoradiation (CRT) on 5-year overall survival (OS) in resected pancreatic adenocarcinoma are presented with updated results of a phase III trial...
Predicting pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer using 18FDG-PET/CTSkandan Shanmugan
Department of Surgery, Temple University, Philadelphia, PA, USA
Ann Surg Oncol 19:2178-85. 2012..The objective of this study was to determine whether PET/CT can predict pCR and disease-free survival in patients receiving CRT with LARC...
Resection of isolated pelvic recurrences after colorectal surgery: long-term results and predictors of improved clinical outcomeLeonard R Henry
Department of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
Ann Surg Oncol 14:2000-9. 2007..Resection offers the only reasonable probability for cure, but at the cost of perioperative morbidity and potential mortality. Clinical decision making remains difficult...
Emotional well-being does not predict survival in head and neck cancer patients: a Radiation Therapy Oncology Group studyJames C Coyne
Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Cancer 110:2568-75. 2007..The objective of the current study was to examine whether emotional well-being predicted survival in a large sample of patients with head and neck cancer who were participating in multicenter clinical trials...
Postresection CA 19-9 predicts overall survival in patients with pancreatic cancer treated with adjuvant chemoradiation: a prospective validation by RTOG 9704Adam C Berger
Thomas Jefferson University, Philadelphia, PA, USA
J Clin Oncol 26:5918-22. 2008..CA 19-9 is an important tumor marker in patients with pancreatic adenocarcinoma. A secondary end point of Radiation Therapy Oncology Group trial 9704 was prospective evaluation of the ability of postresectional CA 19-9 to predict survival...
Induction cisplatin and paclitaxel followed by combination chemoradiotherapy with 5-fluorouracil, cisplatin, and paclitaxel before resection in localized esophageal cancer: a phase II reportLeonard R Henry
Department of Surgical Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, Pennsylvania 19111, USA
Ann Surg Oncol 13:214-20. 2006..The incorporation of taxanes into induction strategies for esophageal cancer seems promising, but the optimal schedule remains undefined...
Economic analysis of a phase III clinical trial evaluating the addition of total androgen suppression to radiation versus radiation alone for locally advanced prostate cancer (Radiation Therapy Oncology Group protocol 86-10)Andre Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Int J Radiat Oncol Biol Phys 63:788-94. 2005..To evaluate the cost-effectiveness of adding hormone therapy to radiation for patients with locally advanced prostate cancer, using a Monte Carlo simulation of a Markov Model...
Symptomatic cardiac toxicity is predicted by dosimetric and patient factors rather than changes in 18F-FDG PET determination of myocardial activity after chemoradiotherapy for esophageal cancerAndre Konski
Department of Radiation Oncology, Wayne State University School of Medicine, Detroit, MI 48201, USA
Radiother Oncol 104:72-7. 2012..To determine factors associated with symptomatic cardiac toxicity in patients with esophageal cancer treated with chemoradiotherapy...
Predictors of preferences and utilities in men treated with 3D-CRT for prostate cancerDeborah Watkins Bruner
Department of Population Science, Fox Chase Cancer Center, Philadelphia, PA, USA
Int J Radiat Oncol Biol Phys 58:34-42. 2004..To assess the preferences and utilities for prostate cancer health state scenarios of men treated with three-dimensional conformal radiotherapy and the predictors of treatment preferences...
Morbidity and mortality are not increased after induction chemoradiotherapy followed by esophagectomy in patients with esophageal cancerAdam C Berger
Department of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
Semin Oncol 32:S16-20. 2005..5 days). Esophagectomy can be performed safely with low mortality and acceptable morbidity following neoadjuvant chemotherapy and radiation with no increase in hospital stay for patients with complications...
Phase I trial of preoperative hypofractionated intensity-modulated radiotherapy with incorporated boost and oral capecitabine in locally advanced rectal cancerGary M Freedman
Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA 19111, USA
Int J Radiat Oncol Biol Phys 67:1389-93. 2007..To determine the safety and efficacy of preoperative hypofractionated radiotherapy using intensity-modulated radiotherapy (IMRT) and an incorporated boost with concurrent capecitabine in patients with locally advanced rectal cancer...
Feasibility of economic analysis of Radiation Therapy Oncology Group (RTOG) 91-11 using Medicare dataAndre Konski
Department of Radiation Oncology, Wayne State University School of Medicine, Detroit, MI 48201, USA
Int J Radiat Oncol Biol Phys 79:436-42. 2011..The specific aim of this analysis was to evaluate the feasibility of performing a cost-effectiveness analysis using Medicare data from patients treated on a randomized Phase III clinical trial...
Significance of pathologic response to preoperative therapy in pancreatic cancerYun Shin Chun
Department of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
Ann Surg Oncol 18:3601-7. 2011..Pathologic response to preoperative therapy is increasingly recognized as an important prognostic factor in solid tumors. The impact of pathologic response on survival in pancreatic adenocarcinoma is not well established...
The integration of 18-fluoro-deoxy-glucose positron emission tomography and endoscopic ultrasound in the treatment-planning process for esophageal carcinomaAndre Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA
Int J Radiat Oncol Biol Phys 61:1123-8. 2005..CONCLUSION: Endoscopic ultrasound and PET scans can add additional information to aid the radiation oncologist's ability to precisely identify the GTV in patients with esophageal carcinoma...
Comparing computed tomography localization with daily ultrasound during image-guided radiation therapy for the treatment of prostate cancer: a prospective evaluationSteven J Feigenberg
Fox Chase Cancer Center, Department of Radiation Oncology, Philadelphia, Pennsylvania 19111, USA
J Appl Clin Med Phys 8:2268. 2007..The isocenter shifts generated by using a CT unit in the treatment room correlate highly with shifts produced by the BAT Ultrasound system...
Radiotherapy is a cost-effective palliative treatment for patients with bone metastasis from prostate cancerAndre Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Int J Radiat Oncol Biol Phys 60:1373-8. 2004..To evaluate the various treatments for patients with hormone-refractory prostate cancer with bone metastases using a Markov model...
Effect of education level on outcome of patients treated on Radiation Therapy Oncology Group Protocol 90-03Andre Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
Cancer 98:1497-503. 2003..The authors investigated this hypothesis by using education level as a proxy for socioeconomic status in patients treated on Radiation Therapy Oncology Group (RTOG) Protocol 90-03...
Fluorouracil vs gemcitabine chemotherapy before and after fluorouracil-based chemoradiation following resection of pancreatic adenocarcinoma: a randomized controlled trialWilliam F Regine
Department of Radiation Oncology, University of Maryland Medical Center, Baltimore 21030, USA
JAMA 299:1019-26. 2008..Among patients with locally advanced metastatic pancreatic adenocarcinoma, gemcitabine has been shown to improve outcomes compared with fluorouracil...
Chemoradiation followed by chemotherapy before resection for borderline pancreatic adenocarcinomaKimberly M Brown
Department of Surgical Oncology, Fox Chase Cancer Center, 333 Cottman Ave Philadelphia, PA 19027, USA
Am J Surg 195:318-21. 2008..For patients with borderline resectable pancreatic cancer, preoperative chemoradiation and standalone chemotherapy may allow for R0 resection and improved survival...
Prostate cancer risk assessment program: a 10-year update of cancer detectionVeda N Giri
Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19012, USA
J Urol 178:1920-4; discussion 1924. 2007..Guidelines for screening men at high risk for prostate cancer remain under investigation. We report our 10-year cancer detection data from the Prostate Cancer Risk Assessment Program, a longitudinal screening program for men at high risk...
The role of qualitative and quantitative analysis of F18-FDG positron emission tomography in predicting pathologic response following chemoradiotherapy in patients with esophageal carcinomaTracy Klayton
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
J Gastrointest Cancer 43:612-8. 2012..The aim of this study was to determine if a qualitative and quantitative assessment of pre- and post-chemoradiotherapy (CRT) F18-FDG PET scans of esophageal cancer patients could predict for residual disease in esophagectomy specimens...
Adjuvant radiation therapy increases overall survival in node-positive gastric cancer patients with aggressive surgical resection and lymph node dissection: a SEER database analysisRavi Shridhar
Department of Radiation Oncology, H Lee Moffitt Cancer Center, Tampa, FL 33512, USA
Am J Clin Oncol 35:216-21. 2012..To determine the outcomes of postoperative radiation therapy on survival in gastric cancer...
Proton beam therapy and the convoluted pathway to incorporating emerging technology into routine medical care in the United StatesMichael L Steinberg
Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 6951, USA
Cancer J 15:333-8. 2009....
Resection of isolated pelvic recurrences after colorectal surgery: long-term results and predictors of improved clinical outcomeLeonard R Henry
Department of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
Ann Surg Oncol 14:1081-91. 2007..Resection offers the only reasonable probability for cure, but at the cost of marked perioperative morbidity and potential mortality. Clinical decision making remains difficult...
Health states of women after conservative surgery and radiation for breast cancerGary M Freedman
Department of Radiation Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
Breast Cancer Res Treat 121:519-26. 2010..These health states are comparable to the adult female U.S. population. These data will provide valuable patient utility information for informing decision analyses investigating new treatments in women with breast cancer...
Stereotactic IMRT for prostate cancer: setup accuracy of a new stereotactic body localization systemLu Wang
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
J Appl Clin Med Phys 5:18-28. 2004..A rigid frame system serves as a reliable alignment reference in terms of repositioning patients into the planning position, while skin-based reference showed larger deviations in repositioning patients...
Unexpected dementia following prophylactic cranial irradiation for small cell lung cancer: case reportDavid J D'Ambrosio
Department of Radiation Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
J Neurooncol 85:77-9. 2007..Prophylactic cranial irradiation (PCI) is commonly offered to patients with limited stage primary small cell lung cancer following a complete response...
Palliative radiation therapyAndre Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Semin Oncol 32:156-64. 2005..Radiation has also been found to be effective in palliating recurrent cancer that has already received definitive radiation...
Palliative radiotherapy for bone metastases: an ASTRO evidence-based guidelineStephen Lutz
Department of Radiation Oncology, Blanchard Valley Regional Cancer Center, Findlay, OH 45840, USA
Int J Radiat Oncol Biol Phys 79:965-76. 2011..To present guidance for patients and physicians regarding the use of radiotherapy in the treatment of bone metastases according to current published evidence and complemented by expert opinion...
Assessment of external beam radiation technology for dose escalation and normal tissue protection in the treatment of prostate cancerAlan Pollack
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Int J Radiat Oncol Biol Phys 70:671-7. 2008
Clinical and economic outcomes analyses of women developing breast cancer in a managed care organizationAndre Konski
Outcomes Department, Paramount Health Care, Toledo, Ohio, USA
Am J Clin Oncol 28:51-7. 2005..An evaluation was performed linking an administrative database to clinical information to determine the clinical and economic outcomes of women presenting with breast cancer in a managed care organization (MCO)...
Survival after pancreatectomy with major arterial resection and reconstructionKaryn B Stitzenberg
Surgical Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
Ann Surg Oncol 15:1399-406. 2008..We hypothesize that resection of a tumor-involved hepatic artery (HA) or celiac artery (CA) with reconstruction may offer a survival benefit to patients whose tumors were traditionally regarded as unresectable...
Dosimetry and preliminary acute toxicity in the first 100 men treated for prostate cancer on a randomized hypofractionation dose escalation trialAlan Pollack
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Int J Radiat Oncol Biol Phys 64:518-26. 2006..The dosimetry and acute toxicity are described in the first 100 men enrolled in a randomized trial...
Patterns of failure in patients with primary intracranial germinoma treated with neoadjuvant chemotherapy and radiotherapyPeter Paximadis
Department of Radiation Oncology, Wayne State University and Detroit Medical Center, Detroit, MI 48201, USA
Pediatr Neurol 47:162-6. 2012..Based on the patterns of failure, our outcomes support the continued use of the whole ventricular field vs a focal field, even in patients with limited disease who demonstrate a complete response to neoadjuvant chemotherapy...
The RTOG Outcomes Model: economic end points and measuresAndre Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Expert Opin Pharmacother 5:513-9. 2004..The RTOG economic analyses have provided information that can further inform clinicians and policy makers of the value added of new or improved treatments...
Economic analysis of health care interventionsAndre Konski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Semin Radiat Oncol 18:168-74. 2008....
FDG PET imaging of signet-ring cell adenocarcinoma of the stomachMark K Buyyounouski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
Clin Nucl Med 30:118-9. 2005
Pretreatment quality of life predicts for locoregional control in head and neck cancer patients: a radiation therapy oncology group analysisFarzan Siddiqui
Department of Radiation Oncology, Henry Ford Health System, Detroit, MI 48202, USA
Int J Radiat Oncol Biol Phys 70:353-60. 2008....
ACR Appropriateness Criteria on treatment of anal cancerMatthew M Poggi
National Naval Medical Center, Department of Radiation Oncology, Bethesda, Md 20889 5000, USA
J Am Coll Radiol 4:448-56. 2007..To this end, anal cancer is a disease best treated primarily with chemoradiation. Although appropriate treatment can produce acceptable results, further investigation and improvement in therapy are still needed...
Compliance of reviewing portal images on radiographic film vs an electronic medical recordGeorge G Chen
Department of Radiation Oncology, Wayne State University School of Medicine and Barbara Ann Karmanos Cancer Center, Detroit, Michigan 48201, USA
J Am Coll Radiol 9:495-7. 2012..The purpose of this study was to compare compliance of reviewing portal images per departmental policy before and after implementing an electronic medical record (EMR)...
Evidence-based review of three-dimensional conformal radiotherapy for localized prostate cancer: an ASTRO outcomes initiativeDavid E Morris
Department of Radiation Oncology, University of North Carolina, Chapel Hill, NC 27514, USA
Int J Radiat Oncol Biol Phys 62:3-19. 2005....
Can physicians accurately predict survival time in patients with metastatic cancer? Analysis of RTOG 97-14William F Hartsell
Department of Radiation Oncology, Advocate Good Samaritan Cancer Center, Downers Grove, Illinois 60515, USA
J Palliat Med 11:723-8. 2008..To determine if physician prediction of survival duration (PSD) is accurate for patients with metastatic breast or prostate cancer...
ACR Appropriateness Criteria on resectable rectal cancer: expert panel on radiation oncology--rectal/anal cancerW Warren Suh
Department of Radiation Oncology, Dana Farber Cancer Institute Brigham and Women s Hospital, Boston, MA 02459, USA
Int J Radiat Oncol Biol Phys 70:1427-30. 2008..A summary of the major randomized clinical trials spanning the past several decades is provided...
American Society for Therapeutic Radiology and Oncology (ASTRO) Emerging Technology Committee report on electronic brachytherapyCatherine C Park
Department of Radiation Oncology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, 1600 Divisadero St, H1031, San Francisco, CA 94143 1708, USA
Int J Radiat Oncol Biol Phys 76:963-72. 2010..The full Emerging Technology Committee report is available on the American Society for Therapeutic Radiology and Oncology Web site...
A review of hypofractionated palliative radiotherapyStephen T Lutz
Department of Radiation Oncology, Blanchard Valley Regional Cancer Center, Findlay, Ohio 45840, USA
Cancer 109:1462-70. 2007..Collaboration in education, research, and patient advocacy will advance the common objectives of the 2 specialties and lead to an appropriate increase in the use of palliative hypofractionated radiotherapy...
Full-dose gemcitabine with concurrent radiation therapy in patients with nonmetastatic pancreatic cancer: a multicenter phase II trialWilliam Small
Robert H Lurie Comprehensive Cancer Center of Northwestern University, 251 East Huron St, LC 178, Chicago, IL 60611, USA
J Clin Oncol 26:942-7. 2008..This study assessed safety and efficacy of full-dose gemcitabine administered before and during concurrent three-dimensional conformal radiation (3D-CRT) in patients with nonmetastatic pancreatic cancer...
Randomized trial of short- versus long-course radiotherapy for palliation of painful bone metastasesWilliam F Hartsell
Advocate Good Samaritan Hospital, Downers Grove, IL, USA
J Natl Cancer Inst 97:798-804. 2005..We investigated whether 8 Gy delivered in a single treatment fraction provides pain and narcotic relief that is equivalent to that of the standard treatment course of 30 Gy delivered in 10 treatment fractions over 2 weeks...
