Research Topics
| J M KaminskiSummaryAffiliation: Fox Chase Cancer Center Country: USA Publications
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Detail Information
Publications
Defining a future role for radiogenic therapyJ M Kaminski
Department of Radiology, Medical College of Georgia, Augusta 30912, USA
Cancer Treat Rev 27:289-94. 2001..g. radiolabelled substance). We have termed this group of therapeutics radiogenic therapy...
Prostate cancer gene therapy and the role of radiationJ M Kaminski
Department of Radiation Oncology, Fox Chase Cancer Center, 7701 Burolme Avenue, Philadelphia, PA 19111, USA
Cancer Treat Rev 28:49-64. 2002..With further technological advances in radiation therapy, gene therapy, and the understanding of prostate cancer biology, gene therapy will potentially have an important role in prostate cancer therapy...
Design of a nonviral vector for site-selective, efficient integration into the human genomeJoseph M Kaminski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
FASEB J 16:1242-7. 2002....
Intracranial fibrosarcoma arising 5 years after chemotherapy alone for glioblastoma multiforme in a childJ M Kaminski
Department of Radiation Oncology, Fox Chase Cancer Center, Albert Einstein Medical Center, Philadelphia, PA, USA
Pediatr Neurosurg 33:257-260. 2000..She remains alive and recurrence-free 7 years following the diagnosis of her second intracranial malignancy...
Metastatic meningioma to the lung with multiple pleural metastasesJ M Kaminski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
Am J Clin Oncol 24:579-82. 2001..We report an interesting case of a malignant meningioma that invaded through the skull in the frontal sinus that later metastasized to the left lung with multiple pulmonary and pleural nodules...
Active integration: new strategies for transgenesisEric T Shinohara
Department of Radiation Oncology, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA
Transgenic Res 16:333-9. 2007..Subsequently, these methods may someday be used for gene therapy in humans...
piggyBac is a flexible and highly active transposon as compared to sleeping beauty, Tol2, and Mos1 in mammalian cellsSareina Chiung-Yuan Wu
Cancer Research Center, Medical College of Georgia, Augusta, GA 30912, USA
Proc Natl Acad Sci U S A 103:15008-13. 2006..The high transposition activity of piggyBac and the flexibility for molecular modification of its transposase suggest the possibility of using it routinely for mammalian transgenesis...
Immunotherapy and prostate cancerJoseph M Kaminski
Department of Radiology, Medical College of Georgia, Augusta, GA 30912, USA
Cancer Treat Rev 29:199-209. 2003..Many obstacles exist in immunotherapy, including vector design, tumouricidal specificity, and tumor evasion, which will have to be overcome in order to realize the maximum therapeutic benefit from this treatment modality...
Site-directed genome modification: nucleic acid and protein modules for targeted integration and gene correctionAndreas F Kolb
Hannah Research Institute, Hannah Research Park, Ayr, UK, KA6 5HL
Trends Biotechnol 23:399-406. 2005..This review will describe recent progress in the development of 'user-targetable' systems, particularly highlighting the application of custom DNA-binding proteins or nucleic acid homology to confer specificity...
Site-directed genome modification: derivatives of DNA-modifying enzymes as targeting toolsCraig J Coates
Department of Entomology, Texas A and M University, College Station, TX 77843, USA
Trends Biotechnol 23:407-19. 2005..In addition, we discuss the approaches that have been taken to improve the efficiency and to modify the site-specificity of these enzymes...
Functional zinc finger/sleeping beauty transposase chimeras exhibit attenuated overproduction inhibitionMatthew H Wilson
Department of Medicine, Division of Genetic Medicine, 529 Light Hall, Vanderbilt University, Nashville, TN 37232-0275, USA
FEBS Lett 579:6205-9. 2005..These findings suggest that SB transposase chimeras may have specific advantages over the native enzyme...
Relationship between prostate volume, prostate-specific antigen nadir, and biochemical controlJoseph M Kaminski
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Int J Radiat Oncol Biol Phys 52:888-92. 2002..PSA nadir did not correlate with bNED status in the favorable patients, but it was strongly predictive in the unfavorable patients. Prostate gland volume was also predictive of bNED failure in the favorable but not the unfavorable group...
Steps toward targeted insertional mutagenesis with class II transposable elementsSareina Chiung Yuan Wu
Department of Entomology, Texas A and M University, College Station, TX
Methods Mol Biol 435:139-51. 2008..Herein, we provide a brief background on targeted transposon integration and detailed protocols for testing chimeric transposases in both mammalian cell culture and insect embryos...
