Research Topics
| E FourkalSummaryAffiliation: Fox Chase Cancer Center Country: USA Publications
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Detail Information
Publications
Particle in cell simulation of laser-accelerated proton beams for radiation therapyE Fourkal
Radiation Oncology Department, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
Med Phys 29:2788-98. 2002..Because of the broad energy and angular spectra of the protons, a compact particle selection and beam collimation system will be needed to generate small beams of polyenergetic protons for intensity modulated proton therapy...
Particle selection for laser-accelerated proton therapy feasibility studyE Fourkal
Radiation Oncology Department, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
Med Phys 30:1660-70. 2003..The calculations presented in this article show that the dose rate that the selection system can yield is on the order of D=260 Gy/min for a field size of 1 x 1 cm2...
Intensity modulated radiation therapy using laser-accelerated protons: a Monte Carlo dosimetric studyE Fourkal
Radiation Oncology Department, Fox Chase Cancer Center, 7701 Borehole Avenue, Philadelphia 19111, USA
Phys Med Biol 48:3977-4000. 2003..It is shown that for a two-beam arrangement (parallel-opposed) it is possible to achieve both superior target coverage with 5% dose inhomogeneity within the target and excellent sparing of surrounding tissue...
Shielding design for a laser-accelerated proton therapy systemJ Fan
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Phys Med Biol 52:3913-30. 2007..It is shown that the two-layer shielding design with 10-12 cm thick polyethylene and 4 cm thick lead can effectively absorb the unwanted particles to meet the shielding requirements...
A particle track-repeating algorithm for proton beam dose calculationJ S Li
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Phys Med Biol 50:1001-10. 2005..The differences between them were within 2%. The new algorithm was about 13 times faster than the GEANT3 Monte Carlo code for a uniform phantom geometry and over 700 times faster for a heterogeneous phantom geometry...
Dosimetric advantages of IMPT over IMRT for laser-accelerated proton beamsW Luo
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Phys Med Biol 53:7151-66. 2008..Significant improvement in target dose uniformity and normal tissue sparing as well as in reduction of whole body dose can be achieved by IMPT with appropriate optimization and beam setup...
Absolute dose reconstruction in proton therapy using PET imaging modality: feasibility studyE Fourkal
Department of Radiation Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA, USA
Phys Med Biol 54:N217-28. 2009..Deconvolution of the calculated activity with the PESM leads to the reconstructed dose being within 2% of that delivered...
Energy optimization procedure for treatment planning with laser-accelerated protonsE Fourkal
Department of Radiation Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, Pennsylvania 19111, USA
Med Phys 34:577-84. 2007....
Stereotactic IMRT for prostate cancer: dosimetric impact of multileaf collimator leaf width in the treatment of prostate cancer with IMRTL Wang
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
J Appl Clin Med Phys 5:29-41. 2004..78). In conclusion, the use of the mMLC for IMRT of the prostate resulted in significant improvement in the DVH parameters of the prostate and critical organs, which may improve the therapeutic ratio...
Linear energy transfer of proton clustersE Fourkal
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Phys Med Biol 56:3123-36. 2011..As a result, the elevated radio biological effectiveness of the proton cluster may take place and conditions for its experimental observation are presented...
Coulomb explosion effect and the maximum energy of protons accelerated by high-power lasersE Fourkal
Department of Radiation Physics, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
Phys Rev E Stat Nonlin Soft Matter Phys 71:036412. 2005..The heavy-ion motion is found to modify the longitudinal electric field distribution, thus changing the acceleration conditions for the protons...
Monitor unit calculation for Monte Carlo treatment planningC M Ma
Radiation Oncology Department, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Phys Med Biol 49:1671-87. 2004..It is also used for absolute dose calculations using Monte Carlo simulations for treatment verification, which has become part of our comprehensive IMRT quality assurance programme...
SU-E-T-590: Procedure for Verification and Inter-Comparison of IMRT Beam ModelsI Veltchev
Fox Chase Cancer Center, Philadelphia, PA
Med Phys 39:3841. 2012..Adoption of a unified strategy for beam model inter-comparison can greatly facilitate the evaluation and commissioning of IMRT beam models...
WE-A-BRB-06: 3D In-Patient Dose Reconstruction from the PET-CT Imaging of Y-90 Microspheres for Metastatic Cancer to the LiverE Fourkal
Fox Chase Cancer Center, Philadelphia, PA
Med Phys 39:3932. 2012....
Investigation into the physical characteristics of active matrix flat panel imagers for radiotherapyM Lachaine
Medical Physics, Cross Cancer Institute and University of Alberta, Edmonton, Canada
Med Phys 28:1689-95. 2001..It is found that for small sensitive layer thicknesses (< or =0.3 mm) a front plate thickness of about 1 mm Cu is optimal, whereas for larger mass thicknesses about 0.4 mm Cu should lead to better image quality...
Detective quantum efficiency of a direct-detection active matrix flat panel imager at megavoltage energiesM Lachaine
Cross Cancer Institute and University of Alberta, Edmonton, Canada
Med Phys 28:1364-72. 2001..The model is used to explore the DQE for more typical pixel sizes. The results indicate that with proper modifications, such as a larger a-Se thickness, a direct flat-panel AMFPI is a very promising detector for megavoltage imaging...
