Research Topics
Species | Efrat DotanSummaryAffiliation: Fox Chase Cancer Center Country: USA Publications
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Detail Information
Publications
A phase II study of capecitabine, oxaliplatin, and cetuximab with or without bevacizumab as frontline therapy for metastatic colorectal cancer. A Fox Chase extramural research studyEfrat Dotan
Department of Medical Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
J Gastrointest Cancer 43:562-9. 2012..This phase II study tested the efficacy and safety of capecitabine, oxaliplatin, and cetuximab with or without bevacizumab as first-line treatment for metastatic colorectal cancer patients...
Relationship of increased aurora kinase A gene copy number, prognosis and response to chemotherapy in patients with metastatic colorectal cancerE Dotan
Department of Medical Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
Br J Cancer 106:748-55. 2012..Expression of AURKA protein was analysed by immunohistochemistry. Cox-proportional hazard method, Kaplan-Meier curves and log-rank statistics were used to estimate and compare the hazard ratios and median survival between the groups...
Challenges in the management of older patients with colon cancerEfrat Dotan
Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA
J Natl Compr Canc Netw 10:213-24; quiz 225. 2012..This review provides an overview of the available data regarding the management of older adults with colon cancer in the adjuvant and metastatic settings...
Challenges in the management of stage II colon cancerEfrat Dotan
Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
Semin Oncol 38:511-20. 2011..Additional research is necessary to clearly define the most appropriate way to use this marker and others in routine clinical practice...
Optimizing chemotherapy regimens for patients with early-stage breast cancerEfrat Dotan
Fox Chase Cancer Center, Philadelphia, PA 19111 2412, USA
Clin Breast Cancer 10:E8-15. 2010..This review summarizes the available tools that can assist in this process and provides an overview of the chemotherapy regimens approved for the adjuvant treatment of patients with early-stage breast cancer...
Circulating tumor cells: evolving evidence and future challengesEfrat Dotan
Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA
Oncologist 14:1070-82. 2009..This review covers the different techniques available for isolation of CTCs, the clinical utility of CTCs in breast, prostate, and colon cancer, and future directions in this field...
