John B Burch

Summary

Affiliation: Fox Chase Cancer Center
Country: USA

Publications

  1. ncbi request reprint Regulation of GATA gene expression during vertebrate development
    John B E Burch
    Cell and Developmental Biology Program, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
    Semin Cell Dev Biol 16:71-81. 2005
  2. ncbi request reprint Transcriptional regulation in the mouse atrioventricular conduction system
    Angela V Edwards
    Department of Cell and Developmental Biology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Novartis Found Symp 250:177-89; discussion 189-93, 276-9. 2003
  3. ncbi request reprint GATA-6 gene enhancer contains nested regulatory modules for primary myocardium and the embedded nascent atrioventricular conduction system
    Richard F Adamo
    Cell Developmental Biology Program, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Anat Rec A Discov Mol Cell Evol Biol 280:1062-71. 2004
  4. pmc Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus
    Vinciane Gaussin
    Department of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, 185 S Orange Ave, MSB Room G 609, Newark, NJ 07103, USA
    Circ Res 97:219-26. 2005
  5. ncbi request reprint Apoptosis in the developing mouse heart
    Laura Barbosky
    Department of Pediatrics, Rainbow Babies and Children s Hospital, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106 6011, USA
    Dev Dyn 235:2592-602. 2006
  6. ncbi request reprint Bone marrow cells transdifferentiate to cardiomyocytes when introduced into the embryonic heart
    Carol A Eisenberg
    Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Stem Cells 24:1236-45. 2006
  7. ncbi request reprint The serosal mesothelium is a major source of smooth muscle cells of the gut vasculature
    Bettina Wilm
    Stahlman Cardiovascular Laboratories, Department of Medicine and Program for Developmental Biology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Development 132:5317-28. 2005
  8. ncbi request reprint Epicardial induction of fetal cardiomyocyte proliferation via a retinoic acid-inducible trophic factor
    Tim H P Chen
    Institute for Genetic Medicine, University of Southern California Keck School of Medicine, 2250 Alcazar St, IGM240, Los Angeles, California 90033, USA
    Dev Biol 250:198-207. 2002
  9. ncbi request reprint Architectural plan for the heart: early patterning and delineation of the chambers and the nodes
    Vincent M Christoffels
    Department of Anatomy and Embryology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Trends Cardiovasc Med 14:301-7. 2004
  10. ncbi request reprint Mouse models for cardiac conduction system development
    Andy Wessels
    Department of Cell Biology and Anatomy, Medical University of South Carolina, 172 Ashley Avenue, Charleston, SC 29425, USA
    Novartis Found Symp 250:44-59; discussion 59-67, 276-9. 2003

Research Grants

Collaborators

  • Vinciane Gaussin
  • ARNO WESSELS
  • S J Conway
  • Jing Liu
  • An Zwijsen
  • A F Moorman
  • ANTHONY FIRULLI
  • Leonard M Eisenberg
  • V M Christoffels
  • Angela V Edwards
  • Andrew Lindsley
  • Carol A Eisenberg
  • Laura Barbosky
  • Bettina Wilm
  • Richard F Adamo
  • Tim H P Chen
  • Michael Olaopa
  • Agnieszka Kruzynska-Frejtag
  • Rhonda Rogers
  • Jian Wang
  • Brenda Lilly
  • Hongming Zhou
  • Shrinagesh V Koushik
  • Paige Snider
  • Richard P Visconti
  • Jamie C Wikenheiser
  • Yong Qiu Doughman
  • Michiko Watanabe
  • David K Lawrence
  • Ganga Karunamuni
  • Annemieke Ipenberg
  • David M Bader
  • Nicholas D Hastie
  • Catherine L Guay
  • Amy L Juraszek
  • Dorene L Davis
  • Ji One Kang
  • Tsai Ching Chang
  • Henry M Sucov
  • Takako Makita
  • Hoda Eid
  • Bibha Choudhary
  • Chanh M Tran

Detail Information

Publications11

  1. ncbi request reprint Regulation of GATA gene expression during vertebrate development
    John B E Burch
    Cell and Developmental Biology Program, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
    Semin Cell Dev Biol 16:71-81. 2005
    ..These enhancers also afford a raft of tools that can be used to selectively perturb and probe various developmental events in transgenic animals...
  2. ncbi request reprint Transcriptional regulation in the mouse atrioventricular conduction system
    Angela V Edwards
    Department of Cell and Developmental Biology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Novartis Found Symp 250:177-89; discussion 189-93, 276-9. 2003
    ..Lastly, we are exploring strategies to isolate and analyse AVCS cells from normal and affected hearts...
  3. ncbi request reprint GATA-6 gene enhancer contains nested regulatory modules for primary myocardium and the embedded nascent atrioventricular conduction system
    Richard F Adamo
    Cell Developmental Biology Program, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Anat Rec A Discov Mol Cell Evol Biol 280:1062-71. 2004
    ..These are the first functional elements to be reported for a cardiac conduction system-specific control region...
  4. pmc Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus
    Vinciane Gaussin
    Department of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, 185 S Orange Ave, MSB Room G 609, Newark, NJ 07103, USA
    Circ Res 97:219-26. 2005
    ..In conclusion, our mouse model demonstrated critical roles for Alk3 signaling in the AV myocardium during the development of AV valves and the annulus fibrosus...
  5. ncbi request reprint Apoptosis in the developing mouse heart
    Laura Barbosky
    Department of Pediatrics, Rainbow Babies and Children s Hospital, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106 6011, USA
    Dev Dyn 235:2592-602. 2006
    ..These findings suggest that cardiomyocyte apoptosis is an evolutionarily conserved mechanism for normal morphogenesis of the outflow tract myocardium in avian and mammalian species...
  6. ncbi request reprint Bone marrow cells transdifferentiate to cardiomyocytes when introduced into the embryonic heart
    Carol A Eisenberg
    Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Stem Cells 24:1236-45. 2006
    ..In addition, the predominance of the macrophage phenotype within the donor bone marrow cell population suggests that transdifferentiation of immune response cells may play a role in cellular regeneration in the adult...
  7. ncbi request reprint The serosal mesothelium is a major source of smooth muscle cells of the gut vasculature
    Bettina Wilm
    Stahlman Cardiovascular Laboratories, Department of Medicine and Program for Developmental Biology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Development 132:5317-28. 2005
    ..Our data reveal a conserved mechanism in blood vessel formation to coelomic organs, and have major implications for our understanding of vertebrate organogenesis and vascular deficiencies of the gut...
  8. ncbi request reprint Epicardial induction of fetal cardiomyocyte proliferation via a retinoic acid-inducible trophic factor
    Tim H P Chen
    Institute for Genetic Medicine, University of Southern California Keck School of Medicine, 2250 Alcazar St, IGM240, Los Angeles, California 90033, USA
    Dev Biol 250:198-207. 2002
    ....
  9. ncbi request reprint Architectural plan for the heart: early patterning and delineation of the chambers and the nodes
    Vincent M Christoffels
    Department of Anatomy and Embryology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Trends Cardiovasc Med 14:301-7. 2004
    ....
  10. ncbi request reprint Mouse models for cardiac conduction system development
    Andy Wessels
    Department of Cell Biology and Anatomy, Medical University of South Carolina, 172 Ashley Avenue, Charleston, SC 29425, USA
    Novartis Found Symp 250:44-59; discussion 59-67, 276-9. 2003
    ..Specifically, we will re-evaluate the concept of the 'primary ring' in the context of the new insights in the development of the AV junction as provided by the respective mouse models described above...
  11. pmc Identification and characterization of a novel Schwann and outflow tract endocardial cushion lineage-restricted periostin enhancer
    Andrew Lindsley
    Cardiovascular Development Group, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Dev Biol 307:340-55. 2007
    ....

Research Grants10

  1. GATA FACTORS AND VERTEBRATE HEART DEVELOPMENT
    John Burch; Fiscal Year: 2000
    ..Defects in this region have been documented in many cardiovascular-associated diseases including Down Syndrome. ..
  2. Transcriptional Regulation in the Developing Heart
    John Burch; Fiscal Year: 2005
    ..We will also attempt to use adjunct cell culture systems to facilitate our analysis of this early-heart-specific enhancer as well as the heart-region-specific enhancer described above. ..
  3. Endothelin Receptor-B Signaling in Neural Crest
    John Burch; Fiscal Year: 2006
    ..abstract_text> ..