M A Berger

Summary

Affiliation: Fox Chase Cancer Center
Country: USA

Publications

  1. ncbi Subunit composition of pre-T cell receptor complexes expressed by primary thymocytes: CD3 delta is physically associated but not functionally required
    M A Berger
    Division of Basic Sciences, Immunobiology Working Group, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    J Exp Med 186:1461-7. 1997
  2. ncbi Signals transduced by CD3epsilon, but not by surface pre-TCR complexes, are able to induce maturation of an early thymic lymphoma in vitro
    M Carleton
    Fox Chase Cancer Center, Immunobiology Working Group, Division of Basic Sciences, Philadelphia, PA 19111, USA
    J Immunol 163:2576-85. 1999

Collaborators

Detail Information

Publications2

  1. ncbi Subunit composition of pre-T cell receptor complexes expressed by primary thymocytes: CD3 delta is physically associated but not functionally required
    M A Berger
    Division of Basic Sciences, Immunobiology Working Group, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    J Exp Med 186:1461-7. 1997
    ..Thus, pre-TCRs do not require the full array of TCR-associated signaling subunits (gamma, delta, epsilon, and zeta), possibly because pT alpha itself possesses signaling capabilities...
  2. ncbi Signals transduced by CD3epsilon, but not by surface pre-TCR complexes, are able to induce maturation of an early thymic lymphoma in vitro
    M Carleton
    Fox Chase Cancer Center, Immunobiology Working Group, Division of Basic Sciences, Philadelphia, PA 19111, USA
    J Immunol 163:2576-85. 1999
    ..Our current working hypothesis is that CD3epsilon fails to promote in vitro maturation when in the context of an Ab-engaged pre-TCR because another pre-TCR subunit(s), possibly TCRzeta, qualitatively alters the CD3epsilon signal...