Research Topics
Species | Bruce A FowlerSummaryCountry: USA Publications
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Publications
Monitoring of human populations for early markers of cadmium toxicity: a reviewBruce A Fowler
Division of Toxicology and Environmental Medicine, Agency for Toxic Substances and Disease Registry, Atlanta, GA 30333, USA
Toxicol Appl Pharmacol 238:294-300. 2009..The emphasis will be on the detection of early toxic effects from exposure to Cd in new products such as nano-materials and identification of populations at special risk for Cd toxicity...
Modification by ALAD of the association between blood lead and blood pressure in the U.S. population: results from the Third National Health and Nutrition Examination SurveyFranco Scinicariello
Division of Toxicology and Environmental Medicine, Agency for Toxic Substances and Disease Registry, Atlanta, Georgia 30341, USA
Environ Health Perspect 118:259-64. 2010..Individuals vary greatly in susceptibility to lead toxicity, and genetic susceptibility has often been cited as the probable cause for such variation...
Lead and delta-aminolevulinic acid dehydratase polymorphism: where does it lead? A meta-analysisFranco Scinicariello
Division of Toxicology and Environmental Medicine, Agency for Toxic Substances and Disease Registry, Centers of Disease Control and Prevention, Atlanta, Georgia 30341, USA
Environ Health Perspect 115:35-41. 2007..Lead poisoning affects many organs in the body. Lead inhibits delta-aminolevulinic acid dehydratase (ALAD), an enzyme with two co-dominantly expressed alleles, ALAD1 and ALAD2...
Interpreting NHANES biomonitoring data, cadmiumPatricia Ruiz
Agency for Toxic Substances and Disease Registry, Atlanta, GA 30333, USA
Toxicol Lett 198:44-8. 2010..The model describes Cd's cumulative nature in humans and accommodates the observed variation in exposure/uptake over the course of a lifetime. Such models may be useful for interpreting biomonitoring data and risk assessment...
SAR/QSAR methods in public health practiceEugene Demchuk
Agency for Toxic Substances and Disease Registry ATSDR, Division of Toxicology and Environmental Medicine, Atlanta, GA 30333, USA
Toxicol Appl Pharmacol 254:192-7. 2011..These cases are illustrated by several examples, which explain how ATSDR applies (Q)SAR methods in public health practice...
Genetic factors that might lead to different responses in individuals exposed to perchlorateFranco Scinicariello
Division of Toxicology, Agency for Toxic Substances and Disease Registry, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
Environ Health Perspect 113:1479-84. 2005..We conclude that future studies linking human disease and environmental perchlorate exposure should consider the genetic makeup of the participants, actual perchlorate exposure levels, and individual iodine intake/excretion levels...
Metal ions affecting the kidneyBruce A Fowler
Division of Toxicology and Environmental Medicine, Agency for Toxic Substances and Disease Registry, Atlanta GA 30341, USA
Met Ions Life Sci 8:133-41. 2011..The issue of interactions between nephrotoxic metals in mixture exposures is discussed in relation to the application of molecular biomarkers for early detection of renal cell injury...
