Douglas J Fort

Summary

Affiliation: Fort Environmental Laboratories
Country: USA

Publications

  1. ncbi request reprint Water conservation--whole effluent toxicity paradox
    Douglas J Fort
    Fort Environmental Laboratories, 515 South Duncan Street, Stillwater, OK 74074, USA
    Water Environ Res 85:483-94. 2013
  2. doi request reprint Triclosan and thyroid-mediated metamorphosis in anurans: differentiating growth effects from thyroid-driven metamorphosis in Xenopus laevis
    Douglas J Fort
    Fort Environmental Laboratories, Stillwater, Oklahoma 74074, USA
    Toxicol Sci 121:292-302. 2011
  3. doi request reprint Triclosan and anuran metamorphosis: no effect on thyroid-mediated metamorphosis in Xenopus laevis
    Douglas J Fort
    Fort Environmental Laboratories, Stillwater, Oklahoma 74074, USA
    Toxicol Sci 113:392-400. 2010
  4. ncbi request reprint The hypothalamic-pituitary-thyroid (HPT) axis in frogs and its role in frog development and reproduction
    Douglas J Fort
    Fort Environmental Laboratories, Stillwater, Oklahoma 74074, USA
    Crit Rev Toxicol 37:117-61. 2007
  5. ncbi request reprint Comparative developmental toxicity of nickel to Gastrophryne carolinensis, Bufo terrestris, and Xenopus laevis
    Douglas J Fort
    Fort Environmental Laboratories, Inc, Stillwater, Oklahoma, USA
    Arch Environ Contam Toxicol 51:703-10. 2006
  6. ncbi request reprint Comparative sensitivity of Xenopus tropicalis and Xenopus laevis as test species for the FETAX model
    Douglas J Fort
    Fort Environmental Laboratories, 1414 South Sangre, Stillwater, OK 74074, USA
    J Appl Toxicol 24:443-57. 2004
  7. ncbi request reprint Effect of methoxychlor on various life stages of Xenopus laevis
    Douglas J Fort
    Fort Environmental Laboratories, 1414 South Sangre Road, Stillwater, Oklahoma 74074, USA
    Toxicol Sci 81:454-66. 2004
  8. ncbi request reprint Evaluation of the developmental and reproductive toxicity of methoxychlor using an anuran (Xenopus tropicalis) chronic exposure model
    Douglas J Fort
    Fort Environmental Laboratories, 1414 South Sangre Road, Stillwater, Oklahoma 74074, USA
    Toxicol Sci 81:443-53. 2004
  9. ncbi request reprint Impact of boron deficiency on Xenopus laevis: a summary of biological effects and potential biochemical roles
    Douglas J Fort
    Fort Environmental Laboratories, Stillwater, OK 74074, USA
    Biol Trace Elem Res 90:117-42. 2002
  10. ncbi request reprint Evaluation of the developmental toxicities of ethanol, acetaldehyde, and thioacetamide using FETAX
    Douglas J Fort
    Fort Environmental Laboratories, 1414 S Sangre Road, Stillwater, OK 74074, USA
    Drug Chem Toxicol 26:23-34. 2003

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Water conservation--whole effluent toxicity paradox
    Douglas J Fort
    Fort Environmental Laboratories, 515 South Duncan Street, Stillwater, OK 74074, USA
    Water Environ Res 85:483-94. 2013
    ....
  2. doi request reprint Triclosan and thyroid-mediated metamorphosis in anurans: differentiating growth effects from thyroid-driven metamorphosis in Xenopus laevis
    Douglas J Fort
    Fort Environmental Laboratories, Stillwater, Oklahoma 74074, USA
    Toxicol Sci 121:292-302. 2011
    ..laevis. The increased growth associated with TCS exposure was not unexpected and is generally consistent with the presence of reduced bacterial stressors in culture...
  3. doi request reprint Triclosan and anuran metamorphosis: no effect on thyroid-mediated metamorphosis in Xenopus laevis
    Douglas J Fort
    Fort Environmental Laboratories, Stillwater, Oklahoma 74074, USA
    Toxicol Sci 113:392-400. 2010
    ..5 or 7.2 microg TCS/l. Our study indicates that environmentally relevant TCS concentrations do not alter the normal course of thyroid-mediated metamorphosis in this standard anuran model...
  4. ncbi request reprint The hypothalamic-pituitary-thyroid (HPT) axis in frogs and its role in frog development and reproduction
    Douglas J Fort
    Fort Environmental Laboratories, Stillwater, Oklahoma 74074, USA
    Crit Rev Toxicol 37:117-61. 2007
    ..The utility of amphibian metamorphosis as a model for evaluating thyroid axis disruption has recently led to the development of a bioassay using Xenopus laevis...
  5. ncbi request reprint Comparative developmental toxicity of nickel to Gastrophryne carolinensis, Bufo terrestris, and Xenopus laevis
    Douglas J Fort
    Fort Environmental Laboratories, Inc, Stillwater, Oklahoma, USA
    Arch Environ Contam Toxicol 51:703-10. 2006
    ..Overall, the present study provides new data regarding the toxicity of Ni to larval amphibian species, which may be useful in the establishment of new aquatic life criteria for Ni...
  6. ncbi request reprint Comparative sensitivity of Xenopus tropicalis and Xenopus laevis as test species for the FETAX model
    Douglas J Fort
    Fort Environmental Laboratories, 1414 South Sangre, Stillwater, OK 74074, USA
    J Appl Toxicol 24:443-57. 2004
    ..Malformation syndromes induced in both species were similar in X. tropicalis and X. laevis. These results suggested that X. tropicalis could be used effectively as a test organism for the FETAX model...
  7. ncbi request reprint Effect of methoxychlor on various life stages of Xenopus laevis
    Douglas J Fort
    Fort Environmental Laboratories, 1414 South Sangre Road, Stillwater, Oklahoma 74074, USA
    Toxicol Sci 81:454-66. 2004
    ..Overall, these results suggested that sensitivity to methoxychlor is most dramatic during the reproductive and metamorphic phases of the life cycle and least sensitive during early embryo-larval development...
  8. ncbi request reprint Evaluation of the developmental and reproductive toxicity of methoxychlor using an anuran (Xenopus tropicalis) chronic exposure model
    Douglas J Fort
    Fort Environmental Laboratories, 1414 South Sangre Road, Stillwater, Oklahoma 74074, USA
    Toxicol Sci 81:443-53. 2004
    ..These studies add to the standardization and validation of a useful amphibian test methods capable of evaluating both reproductive and developmental effects of potential endocrine disrupting chemicals over a life cycle exposure...
  9. ncbi request reprint Impact of boron deficiency on Xenopus laevis: a summary of biological effects and potential biochemical roles
    Douglas J Fort
    Fort Environmental Laboratories, Stillwater, OK 74074, USA
    Biol Trace Elem Res 90:117-42. 2002
    ..laevis. Combined together, this research program provides firm evidence that B is nutritionally essential in X. laevis...
  10. ncbi request reprint Evaluation of the developmental toxicities of ethanol, acetaldehyde, and thioacetamide using FETAX
    Douglas J Fort
    Fort Environmental Laboratories, 1414 S Sangre Road, Stillwater, OK 74074, USA
    Drug Chem Toxicol 26:23-34. 2003
    ..These results warrant the continued use of FETAX as a means of evaluating mechanisms of developmental toxicity in vitro...
  11. ncbi request reprint Effect of endocrine disrupting chemicals on germinal vesicle breakdown in Xenopus in vitro
    Douglas J Fort
    Fort Environmental Laboratories, 1414 S Sangre Road, Stillwater, OK 74074, USA
    Drug Chem Toxicol 25:293-308. 2002
    ..However, the relative binding affinity of the toxicants to the OMPR can be expressed as P >> EGME > EE > Cd > B. Although EE was more effective in inhibiting GVBD, EGME appeared to bind more tightly to the OMPR...
  12. ncbi request reprint Enhancing the predictive validity of Frog Embryo Teratogenesis Assay--Xenopus (FETAX)
    Douglas J Fort
    Fort Environmental Laboratories, Inc, 1414 S Sangre Road, Stillwater, OK 74074, USA
    J Appl Toxicol 22:185-91. 2002
    ..Data were evaluated for repeatability, predictability and variability. Results from this study indicated that this scoring approach increased repeatability, test endpoint precision and predictability...
  13. ncbi request reprint Boron deficiency disables Xenopus laevis oocyte maturation events
    Douglas J Fort
    Fort Environmental Laboratories, Stillwater, OK 74074, USA
    Biol Trace Elem Res 85:157-69. 2002
    ..Moreover, washout studies determined that progesterone binding to the OMPR in B-deficient oocytes was more transient than the B adequate or +B oocytes...
  14. ncbi request reprint Evaluation of Xenopus tropicalis as an alternative test organism for frog embryo teratogenesis assay--Xenopus (FETAX)
    Min Ok Song
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    Drug Chem Toxicol 26:177-89. 2003
    ..Malformation syndromes induced in both species were similar in X. tropicalis and X. laevis. These results suggested that X. tropicalis should be further evaluated as an alternative test organism for the FETAX model...