Joshua M Costin

Summary

Affiliation: Fort Myers
Country: USA

Publications

  1. pmc Neutralizing and non-neutralizing monoclonal antibodies against dengue virus E protein derived from a naturally infected patient
    John S Schieffelin
    Section of Pediatric Infectious Disease, Department of Pediatrics, Tulane University School of Medicine, New Orleans, LA, USA
    Virol J 7:28. 2010
  2. pmc Cytopathic mechanisms of HIV-1
    Joshua M Costin
    Biotechnology Research Group, Department of Biology, Florida Gulf Coast University, 10501 FGCU Blvd, S, Fort Myers, FL 33965, USA
    Virol J 4:100. 2007
  3. pmc Viroporin potential of the lentivirus lytic peptide (LLP) domains of the HIV-1 gp41 protein
    Joshua M Costin
    Biotechnology Research Group, Department of Biology, Florida Gulf Coast University, 10501 FGCU Blvd S, Fort Myers, FL 33965, USA
    Virol J 4:123. 2007
  4. pmc Mechanistic study of broadly neutralizing human monoclonal antibodies against dengue virus that target the fusion loop
    Joshua M Costin
    Department of Biological Sciences, Florida Gulf Coast University, Fort Myers, Florida, USA
    J Virol 87:52-66. 2013
  5. doi request reprint Viral entry inhibitors block dengue antibody-dependent enhancement in vitro
    Cindo O Nicholson
    Department of Biological Sciences, Florida Gulf Coast University, Fort Myers, FL 33965, USA
    Antiviral Res 89:71-4. 2011
  6. doi request reprint In vitro inhibition of dengue virus entry by p-sulfoxy-cinnamic acid and structurally related combinatorial chemistries
    Craig R Rees
    Biotechnology Research Group, Department of Biological Sciences, Florida Gulf Coast University, Fort Myers, FL 33965, USA
    Antiviral Res 80:135-42. 2008
  7. pmc Structural optimization and de novo design of dengue virus entry inhibitory peptides
    Joshua M Costin
    Department of Biological Sciences, Florida Gulf Coast University, Fort Myers, Florida, United States of America
    PLoS Negl Trop Dis 4:e721. 2010

Detail Information

Publications7

  1. pmc Neutralizing and non-neutralizing monoclonal antibodies against dengue virus E protein derived from a naturally infected patient
    John S Schieffelin
    Section of Pediatric Infectious Disease, Department of Pediatrics, Tulane University School of Medicine, New Orleans, LA, USA
    Virol J 7:28. 2010
    ..Naturally occurring human monoclonal antibodies can help us understand the protective and pathogenic roles of the humoral immune system in dengue virus infection...
  2. pmc Cytopathic mechanisms of HIV-1
    Joshua M Costin
    Biotechnology Research Group, Department of Biology, Florida Gulf Coast University, 10501 FGCU Blvd, S, Fort Myers, FL 33965, USA
    Virol J 4:100. 2007
    ..This review gathers information on TM in an attempt to shed some light on the functional regions of this protein...
  3. pmc Viroporin potential of the lentivirus lytic peptide (LLP) domains of the HIV-1 gp41 protein
    Joshua M Costin
    Biotechnology Research Group, Department of Biology, Florida Gulf Coast University, 10501 FGCU Blvd S, Fort Myers, FL 33965, USA
    Virol J 4:123. 2007
    ..These sequences have been dubbed lentiviral lytic peptides (LLP) -1, -2, and -3...
  4. pmc Mechanistic study of broadly neutralizing human monoclonal antibodies against dengue virus that target the fusion loop
    Joshua M Costin
    Department of Biological Sciences, Florida Gulf Coast University, Fort Myers, Florida, USA
    J Virol 87:52-66. 2013
    ..Characterization of hMAbs targeting this region may provide new insights into DENV vaccine and therapeutic strategies...
  5. doi request reprint Viral entry inhibitors block dengue antibody-dependent enhancement in vitro
    Cindo O Nicholson
    Department of Biological Sciences, Florida Gulf Coast University, Fort Myers, FL 33965, USA
    Antiviral Res 89:71-4. 2011
    ..Both peptides were able to inhibit ADE, showing that entry inhibitors are possible candidates for the development of specific treatment for severe DENV infection...
  6. doi request reprint In vitro inhibition of dengue virus entry by p-sulfoxy-cinnamic acid and structurally related combinatorial chemistries
    Craig R Rees
    Biotechnology Research Group, Department of Biological Sciences, Florida Gulf Coast University, Fort Myers, FL 33965, USA
    Antiviral Res 80:135-42. 2008
    ..These and other related chemistries may be useful as reagents for studying DENV entry, capturing and detecting DENV, and development of pharmaceuticals...
  7. pmc Structural optimization and de novo design of dengue virus entry inhibitory peptides
    Joshua M Costin
    Department of Biological Sciences, Florida Gulf Coast University, Fort Myers, Florida, United States of America
    PLoS Negl Trop Dis 4:e721. 2010
    ..These peptides may be useful for characterization of intermediate states in the membrane fusion process, investigation of DENV receptor molecules, and as lead compounds for drug discovery...