Jiangqin Zhao

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. pmc Rapid detection and differentiation of swine-origin influenza A virus (H1N1/2009) from other seasonal influenza A viruses
    Jiangqin Zhao
    Laboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Viruses 4:3012-9. 2012
  2. pmc Multiplexed, rapid detection of H5N1 using a PCR-free nanoparticle-based genomic microarray assay
    Jiangqin Zhao
    Lab of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    BMC Biotechnol 10:74. 2010
  3. doi request reprint Some mechanisms of FLIP expression in inhibition of HIV-1 replication in Jurkat cells, CD4+ T cells and PBMCs
    Jiying Tan
    Laboratory of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland
    J Cell Physiol 228:2305-13. 2013
  4. pmc CRF22_01A1 is involved in the emergence of new HIV-1 recombinants in Cameroon
    Jiangqin Zhao
    Laboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 RockvillePike, Bethesda, MD 20892, USA
    J Acquir Immune Defic Syndr 60:344-50. 2012
  5. pmc Characterization of immune responses to capsid protein p24 of human immunodeficiency virus type 1 and implications for detection
    Shixing Tang
    Lab of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, USA
    Clin Vaccine Immunol 17:1244-51. 2010
  6. doi request reprint HIV-1 and HIV-2 infections induce autophagy in Jurkat and CD4+ T cells
    Xue Wang
    Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, United States
    Cell Signal 24:1414-9. 2012
  7. pmc Absence of detectable XMRV and other MLV-related viruses in healthy blood donors in the United States
    Shixing Tang
    Lab of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, United States of America
    PLoS ONE 6:e27391. 2011
  8. pmc Identification of new, emerging HIV-1 unique recombinant forms and drug resistant viruses circulating in Cameroon
    Viswanath Ragupathy
    Lab of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Virol J 8:185. 2011
  9. pmc Identification and genetic characterization of a novel CRF22_01A1 recombinant form of HIV type 1 in Cameroon
    Jiangqin Zhao
    Laboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA
    AIDS Res Hum Retroviruses 26:1033-45. 2010
  10. doi request reprint Novel pandemic influenza A (H1N1) virus infection modulates apoptotic pathways that impact its replication in A549 cells
    Xue Wang
    Lab of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, Bethesda, MD 20892, USA Electronic address
    Microbes Infect 16:178-86. 2014

Detail Information

Publications21

  1. pmc Rapid detection and differentiation of swine-origin influenza A virus (H1N1/2009) from other seasonal influenza A viruses
    Jiangqin Zhao
    Laboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Viruses 4:3012-9. 2012
    ..This new method may be useful for simultaneous detection and subtyping of influenza A viruses and can be rapidly modified to detect other emerging influenza strains in public health settings...
  2. pmc Multiplexed, rapid detection of H5N1 using a PCR-free nanoparticle-based genomic microarray assay
    Jiangqin Zhao
    Lab of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    BMC Biotechnol 10:74. 2010
    ....
  3. doi request reprint Some mechanisms of FLIP expression in inhibition of HIV-1 replication in Jurkat cells, CD4+ T cells and PBMCs
    Jiying Tan
    Laboratory of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland
    J Cell Physiol 228:2305-13. 2013
    ..We also found that cFLIP expression downregulated Fas expression and inactivated FADD in the Fas-mediated apoptotic pathway. The inactivated FADD also inhibited HIV-1 replication...
  4. pmc CRF22_01A1 is involved in the emergence of new HIV-1 recombinants in Cameroon
    Jiangqin Zhao
    Laboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 RockvillePike, Bethesda, MD 20892, USA
    J Acquir Immune Defic Syndr 60:344-50. 2012
    ..Our studies show that novel recombinants between CRF22_01A1 and other clades and recombinant forms may be emerging in Cameroon that could contribute to the future global diversity of HIV-1 in this region and worldwide...
  5. pmc Characterization of immune responses to capsid protein p24 of human immunodeficiency virus type 1 and implications for detection
    Shixing Tang
    Lab of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, USA
    Clin Vaccine Immunol 17:1244-51. 2010
    ..The data provide the foundation for development and refinement of new assays for improved p24 antigen testing as future tools for rapid and accurate diagnosis as part of early intervention strategies and estimations of incidence...
  6. doi request reprint HIV-1 and HIV-2 infections induce autophagy in Jurkat and CD4+ T cells
    Xue Wang
    Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, United States
    Cell Signal 24:1414-9. 2012
    ..The results indicate that HIV is able to induce the autophagic signaling pathway in HIV-infected host cells, which may be required for HIV infection-mediated apoptotic cell death...
  7. pmc Absence of detectable XMRV and other MLV-related viruses in healthy blood donors in the United States
    Shixing Tang
    Lab of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, United States of America
    PLoS ONE 6:e27391. 2011
    ..S. These results imply that millions of persons in the U.S. may be carrying the nucleic acid sequences of XMRV and/or MLV-related viruses, which is a serious public health and blood safety concern...
  8. pmc Identification of new, emerging HIV-1 unique recombinant forms and drug resistant viruses circulating in Cameroon
    Viswanath Ragupathy
    Lab of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Virol J 8:185. 2011
    ..The goal of our study was to determine recent trends in virus evolution and emergence of drug resistance in blood donors and HIV positive patients...
  9. pmc Identification and genetic characterization of a novel CRF22_01A1 recombinant form of HIV type 1 in Cameroon
    Jiangqin Zhao
    Laboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA
    AIDS Res Hum Retroviruses 26:1033-45. 2010
    ....
  10. doi request reprint Novel pandemic influenza A (H1N1) virus infection modulates apoptotic pathways that impact its replication in A549 cells
    Xue Wang
    Lab of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, Bethesda, MD 20892, USA Electronic address
    Microbes Infect 16:178-86. 2014
    ..In the p38 superfamily, p38α expression increased viral RNA production, while expression of p38β and p38γ decreased. These data indicated that influenza virus induces apoptotic signaling pathways, which benefit virus replication...
  11. ncbi request reprint Development of a microchip Europium nanoparticle immunoassay for sensitive point-of-care HIV detection
    Jikun Liu
    Laboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA Electronic address
    Biosens Bioelectron 61:177-83. 2014
    ....
  12. doi request reprint Changes in the level of apoptosis-related proteins in Jurkat cells infected with HIV-1 versus HIV-2
    Xue Wang
    Labaratory of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Mol Cell Biochem 337:175-83. 2010
    ....
  13. doi request reprint Molecules from apoptotic pathways modulate HIV-1 replication in Jurkat cells
    Xue Wang
    Laboratory of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Biochem Biophys Res Commun 414:20-4. 2011
    ..We also discuss the effects of MAPK signaling pathways and apoptosis on HIV-1 replication...
  14. doi request reprint c-FLIPL regulates PKC via AP-2 to inhibit Bax-mediated apoptosis induced by HIV-1 gp120 in Jurkat cells
    Xue Wang
    Laboratory of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Building 29B, Rm 4NN16, 8800 Rockville Pike, Bethesda, MD, 20892, USA
    Mol Cell Biochem 330:23-9. 2009
    ..Collectively, these findings further corroborate the concept that gp120 plays an important role, via involvement of molecules such as c-FLIPL, in apoptotic cell death due to HIV-1 infection...
  15. pmc Absence of detectable xenotropic murine leukemia virus-related virus in plasma or peripheral blood mononuclear cells of human immunodeficiency virus type 1-infected blood donors or individuals in Africa
    Shixing Tang
    Laboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA
    Transfusion 51:463-8. 2011
    ....
  16. pmc Viremia associated with fatal outcomes in ferrets infected with avian H5N1 influenza virus
    Xue Wang
    Lab of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, Food and Drug Administration, Bethesda, Maryland, USA
    PLoS ONE 5:e12099. 2010
    ..Our observations further substantiate pathogenicity of H5N1 and further indicate that viremia may be a bio-marker for fatal outcomes in H5N1 infection...
  17. ncbi request reprint Highly pathogenic avian influenza A virus (H5N1) can be transmitted in ferrets by transfusion
    Xue Wang
    Lab of Molecular Virology, Building 29B, Rm 4NN22, Division of Emerging and Transfusion Transmitted Diseases, CBER FDA, 8800 Rockville Pike, Bethesda, MD 20892, USA
    BMC Infect Dis 14:192. 2014
    ..The infectivity of virus in blood and the potential for virus transmission by transfusion has not been investigated...
  18. pmc Stability and infectivity of novel pandemic influenza A (H1N1) virus in blood-derived matrices under different storage conditions
    Xue Wang
    Laboratory of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, CBER FDA, Bethesda, MD 20892, USA
    BMC Infect Dis 11:354. 2011
    ..Furthermore the effect of storage on virus stability and infectivity has not been well studied...
  19. ncbi request reprint Some findings of FADD knockdown in inhibition of HIV-1 replication in Jurkat cells and PBMCs
    Xue Wang
    Lab of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Building 29B, Rm 4NN22 8800 Rockville Pike, Bethesda, MD, 20892, USA
    Mol Cell Biochem 393:181-90. 2014
    ....
  20. pmc Detection of anthrax toxin by an ultrasensitive immunoassay using europium nanoparticles
    Shixing Tang
    Laboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA
    Clin Vaccine Immunol 16:408-13. 2009
    ..These results indicate that the universal labeling technology based on europium nanoparticles and its application may provide a rapid and sensitive testing platform for clinical diagnosis and laboratory research...
  21. ncbi request reprint Nanoparticle-Based biobarcode amplification assay (BCA) for sensitive and early detection of human immunodeficiency type 1 capsid (p24) antigen
    Shixing Tang
    Lab of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    J Acquir Immune Defic Syndr 46:231-7. 2007
    ....