Research Topics
Genomes and Genes | Jiangqin ZhaoSummaryAffiliation: Food and Drug Administration Country: USA Publications
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Detail Information
Publications
Rapid detection and differentiation of swine-origin influenza A virus (H1N1/2009) from other seasonal influenza A virusesJiangqin Zhao
Laboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
Viruses 4:3012-9. 2012..This new method may be useful for simultaneous detection and subtyping of influenza A viruses and can be rapidly modified to detect other emerging influenza strains in public health settings...
Multiplexed, rapid detection of H5N1 using a PCR-free nanoparticle-based genomic microarray assayJiangqin Zhao
Lab of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
BMC Biotechnol 10:74. 2010....
CRF22_01A1 is involved in the emergence of new HIV-1 recombinants in CameroonJiangqin Zhao
Laboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 RockvillePike, Bethesda, MD 20892, USA
J Acquir Immune Defic Syndr 60:344-50. 2012..Our studies show that novel recombinants between CRF22_01A1 and other clades and recombinant forms may be emerging in Cameroon that could contribute to the future global diversity of HIV-1 in this region and worldwide...
Characterization of immune responses to capsid protein p24 of human immunodeficiency virus type 1 and implications for detectionShixing Tang
Lab of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, USA
Clin Vaccine Immunol 17:1244-51. 2010..The data provide the foundation for development and refinement of new assays for improved p24 antigen testing as future tools for rapid and accurate diagnosis as part of early intervention strategies and estimations of incidence...
HIV-1 and HIV-2 infections induce autophagy in Jurkat and CD4+ T cellsXue Wang
Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, United States
Cell Signal 24:1414-9. 2012..The results indicate that HIV is able to induce the autophagic signaling pathway in HIV-infected host cells, which may be required for HIV infection-mediated apoptotic cell death...
Absence of detectable XMRV and other MLV-related viruses in healthy blood donors in the United StatesShixing Tang
Lab of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, United States of America
PLoS ONE 6:e27391. 2011..S. These results imply that millions of persons in the U.S. may be carrying the nucleic acid sequences of XMRV and/or MLV-related viruses, which is a serious public health and blood safety concern...
Identification of new, emerging HIV-1 unique recombinant forms and drug resistant viruses circulating in CameroonViswanath Ragupathy
Lab of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
Virol J 8:185. 2011..The goal of our study was to determine recent trends in virus evolution and emergence of drug resistance in blood donors and HIV positive patients...
Identification and genetic characterization of a novel CRF22_01A1 recombinant form of HIV type 1 in CameroonJiangqin Zhao
Laboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA
AIDS Res Hum Retroviruses 26:1033-45. 2010....
Changes in the level of apoptosis-related proteins in Jurkat cells infected with HIV-1 versus HIV-2Xue Wang
Labaratory of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
Mol Cell Biochem 337:175-83. 2010....
c-FLIPL regulates PKC via AP-2 to inhibit Bax-mediated apoptosis induced by HIV-1 gp120 in Jurkat cellsXue Wang
Laboratory of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Building 29B, Rm 4NN16, 8800 Rockville Pike, Bethesda, MD, 20892, USA
Mol Cell Biochem 330:23-9. 2009..Collectively, these findings further corroborate the concept that gp120 plays an important role, via involvement of molecules such as c-FLIPL, in apoptotic cell death due to HIV-1 infection...
Molecules from apoptotic pathways modulate HIV-1 replication in Jurkat cellsXue Wang
Laboratory of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
Biochem Biophys Res Commun 414:20-4. 2011..We also discuss the effects of MAPK signaling pathways and apoptosis on HIV-1 replication...
Absence of detectable xenotropic murine leukemia virus-related virus in plasma or peripheral blood mononuclear cells of human immunodeficiency virus Type 1-infected blood donors or individuals in AfricaShixing Tang
Laboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA
Transfusion 51:463-8. 2011....
Viremia associated with fatal outcomes in ferrets infected with avian H5N1 influenza virusXue Wang
Lab of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, Food and Drug Administration, Bethesda, Maryland, USA
PLoS ONE 5:e12099. 2010..Our observations further substantiate pathogenicity of H5N1 and further indicate that viremia may be a bio-marker for fatal outcomes in H5N1 infection...
Stability and infectivity of novel pandemic influenza A (H1N1) virus in blood-derived matrices under different storage conditionsXue Wang
Laboratory of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, CBER FDA, Bethesda, MD 20892, USA
BMC Infect Dis 11:354. 2011..Furthermore the effect of storage on virus stability and infectivity has not been well studied...
Detection of anthrax toxin by an ultrasensitive immunoassay using europium nanoparticlesShixing Tang
Laboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA
Clin Vaccine Immunol 16:408-13. 2009..These results indicate that the universal labeling technology based on europium nanoparticles and its application may provide a rapid and sensitive testing platform for clinical diagnosis and laboratory research...
Nanoparticle-Based biobarcode amplification assay (BCA) for sensitive and early detection of human immunodeficiency type 1 capsid (p24) antigenShixing Tang
Lab of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
J Acquir Immune Defic Syndr 46:231-7. 2007....
