M Zaitseva

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. ncbi Interferon gamma and interleukin 6 modulate the susceptibility of macrophages to human immunodeficiency virus type 1 infection
    M Zaitseva
    Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Blood 96:3109-17. 2000
  2. ncbi Stromal-derived factor 1 expression in the human thymus
    Marina Zaitseva
    Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, and Dermatology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 168:2609-17. 2002
  3. ncbi Increased CXCR4-dependent HIV-1 fusion in activated T cells: role of CD4/CXCR4 association
    Marina Zaitseva
    Center for Biologics Evaluation and Research, Food and Drug Administration, Building 29B, Room 4NN06, 8800 Rockville Pike, Bethesda, MD 20892, USA
    J Leukoc Biol 78:1306-17. 2005
  4. ncbi Human peripheral blood T cells, monocytes, and macrophages secrete macrophage inflammatory proteins 1alpha and 1beta following stimulation with heat-inactivated Brucella abortus
    M Zaitseva
    Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA
    Infect Immun 69:3817-26. 2001
  5. ncbi Increased association of glycoprotein 120-CD4 with HIV type 1 coreceptors in the presence of complex-enhanced anti-CD4 monoclonal antibodies
    H Golding
    Division of Viral Products, CBER, Food and Drug Administration, Bethesda, Maryland 20892, USA
    AIDS Res Hum Retroviruses 15:149-59. 1999
  6. ncbi Immunity and protection against Brucella abortus
    B Golding
    Division of Hematology, Office of Blood and Blood Research, Center for Biologics Research and Review, Food and Drug Administration, 1401 Woodmont, Rockville Pike, MD 20852, USA
    Microbes Infect 3:43-8. 2001
  7. ncbi Peptides trap the human immunodeficiency virus type 1 envelope glycoprotein fusion intermediate at two sites
    Yong He
    Center for Biologics Evaluation and Research, Food and Drug Administration, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Virol 77:1666-71. 2003
  8. ncbi Dissection of human immunodeficiency virus type 1 entry with neutralizing antibodies to gp41 fusion intermediates
    Hana Golding
    Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bldg 29A Room 1A21, 8800 Rockville Pike, Bethesda, MD 20892, USA
    J Virol 76:6780-90. 2002
  9. ncbi HIV coreceptors: role of structure, posttranslational modifications, and internalization in viral-cell fusion and as targets for entry inhibitors
    Marina Zaitseva
    Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, USA
    Biochim Biophys Acta 1614:51-61. 2003
  10. ncbi Up-regulation of IL-7, stromal-derived factor-1 alpha, thymus-expressed chemokine, and secondary lymphoid tissue chemokine gene expression in the stromal cells in response to thymocyte depletion: implication for thymus reconstitution
    Iryna Zubkova
    Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    J Immunol 175:2321-30. 2005

Collaborators

Detail Information

Publications11

  1. ncbi Interferon gamma and interleukin 6 modulate the susceptibility of macrophages to human immunodeficiency virus type 1 infection
    M Zaitseva
    Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Blood 96:3109-17. 2000
    ....
  2. ncbi Stromal-derived factor 1 expression in the human thymus
    Marina Zaitseva
    Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, and Dermatology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 168:2609-17. 2002
    ..It was further demonstrated that uptake of apoptotic thymocytes by immature DC induced an increase in CXCR4 expression and SDF-1-mediated chemotaxis. Our data suggest a role for SDF-1 in the elimination of apoptotic thymocytes...
  3. ncbi Increased CXCR4-dependent HIV-1 fusion in activated T cells: role of CD4/CXCR4 association
    Marina Zaitseva
    Center for Biologics Evaluation and Research, Food and Drug Administration, Building 29B, Room 4NN06, 8800 Rockville Pike, Bethesda, MD 20892, USA
    J Leukoc Biol 78:1306-17. 2005
    ..The CD4-CXCR4 complexes may shuttle between late endosomes and the cell surface...
  4. ncbi Human peripheral blood T cells, monocytes, and macrophages secrete macrophage inflammatory proteins 1alpha and 1beta following stimulation with heat-inactivated Brucella abortus
    M Zaitseva
    Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA
    Infect Immun 69:3817-26. 2001
    ....
  5. ncbi Increased association of glycoprotein 120-CD4 with HIV type 1 coreceptors in the presence of complex-enhanced anti-CD4 monoclonal antibodies
    H Golding
    Division of Viral Products, CBER, Food and Drug Administration, Bethesda, Maryland 20892, USA
    AIDS Res Hum Retroviruses 15:149-59. 1999
    ..These data suggest that conformational changes in the CDR3 region of CD4-D1, induced by gp120 binding, may be involved in coreceptor association and thus play a positive role in the HIV-1 cell fusion process...
  6. ncbi Immunity and protection against Brucella abortus
    B Golding
    Division of Hematology, Office of Blood and Blood Research, Center for Biologics Research and Review, Food and Drug Administration, 1401 Woodmont, Rockville Pike, MD 20852, USA
    Microbes Infect 3:43-8. 2001
    ..The response against B. abortus involves the whole gamut of the immune system, from innate to adaptive immunity resulting from stimulation of antigen-presenting cells, NK cells, CD4(+) and CD8(+) T cells, and B cells...
  7. ncbi Peptides trap the human immunodeficiency virus type 1 envelope glycoprotein fusion intermediate at two sites
    Yong He
    Center for Biologics Evaluation and Research, Food and Drug Administration, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Virol 77:1666-71. 2003
    ..These results indicate that there are two distinct sites in receptor-activated Env that are potential targets for drug or vaccine development...
  8. ncbi Dissection of human immunodeficiency virus type 1 entry with neutralizing antibodies to gp41 fusion intermediates
    Hana Golding
    Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bldg 29A Room 1A21, 8800 Rockville Pike, Bethesda, MD 20892, USA
    J Virol 76:6780-90. 2002
    ..They also indicate that six-helix bundles can form prior to fusion and that the lag time before fusion occurs may include the time needed to accumulate preformed six-helix bundles at the fusion site...
  9. ncbi HIV coreceptors: role of structure, posttranslational modifications, and internalization in viral-cell fusion and as targets for entry inhibitors
    Marina Zaitseva
    Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, USA
    Biochim Biophys Acta 1614:51-61. 2003
    ..We also summarize the classes of coreceptor inhibitors under development...
  10. ncbi Up-regulation of IL-7, stromal-derived factor-1 alpha, thymus-expressed chemokine, and secondary lymphoid tissue chemokine gene expression in the stromal cells in response to thymocyte depletion: implication for thymus reconstitution
    Iryna Zubkova
    Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    J Immunol 175:2321-30. 2005
    ..Thus, our data showed for the first time that expression of IL-7, SDF-1alpha, TECK, and SLC mRNA is induced in the thymic stroma during T cell depletion and may play an important role in the reconstitution of the adult thymus...
  11. ncbi Regeneration of the adult thymus is preceded by the expansion of K5+K8+ epithelial cell progenitors and by increased expression of Trp63, cMyc and Tcf3 transcription factors in the thymic stroma
    Ileana Popa
    Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, USA
    Int Immunol 19:1249-60. 2007
    ..These results suggest that TEC progenitors could be reactivated in the adult thymus and, therefore, reactivation of TEC progenitors could provide a new approach for thymic reconstitution...