Research Topics
| Mei Ying W YuSummaryAffiliation: Food and Drug Administration Country: USA Publications
| Collaborators
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Detail Information
Publications
Neutralizing antibodies to hepatitis C virus (HCV) in immune globulins derived from anti-HCV-positive plasmaMei Ying W Yu
Division of Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, 29 Lincoln Drive, Bethesda, MD 20892, USA
Proc Natl Acad Sci U S A 101:7705-10. 2004..Immune globulins made from anti-HCV-positive plasma and containing broadly reactive neutralizing antibodies may provide a method of preventing HCV infection...
Neutralization epitope responsible for the hepatitis B virus subtype-specific protection in chimpanzeesPei Zhang
Division of Hematology and Laboratory of Biophysics, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
Proc Natl Acad Sci U S A 103:9214-9. 2006....
Persistent growth of a human plasma-derived hepatitis C virus genotype 1b isolate in cell cultureErica Silberstein
Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA
PLoS Pathog 6:e1000910. 2010..This virus constitutes a novel tool for the study of one of the most relevant strains of HCV, genotype 1b, which will now be available for HCV life cycle research and useful for the development of new therapeutics...
Parvovirus B19 infection transmitted by transfusion of red blood cells confirmed by molecular analysis of linked donor and recipient samplesMei Ying W Yu
Division of Hematology, Center for Biologics Evaluation and Research, FDA, Warren Grant Magnuson Clinical Center, NIH, Bethesda, Maryland 20892, USA
Transfusion 50:1712-21. 2010..However, reports of transmission by single-donor blood components are rare. In this prospective study, paired donor-recipient samples were used to investigate the transfusion risk...
Parvovirus B19 DNA in Factor VIII concentrates: effects of manufacturing procedures and B19 screening by nucleic acid testingYansheng Geng
Division of Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA
Transfusion 47:883-9. 2007..In this study, the extent of B19 DNA contamination in commercial Factor VIII concentrates, that is, antihemophilic factor (human) (AHF), manufactured before and after B19 NAT screening was implemented, was determined...
Hepatitis C virus epitope-specific neutralizing antibodies in Igs prepared from human plasmaPei Zhang
Division of Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, 29 Lincoln Drive, Bethesda, MD 20892, USA
Proc Natl Acad Sci U S A 104:8449-54. 2007....
Quantification of hepatitis B virus genomes and infectivity in human serum samplesChu Chieh Hsia
Division of Emerging and Transfusion Transmitted Diseases, CBER, FDA, Bethesda, Maryland, USA
Transfusion 46:1829-35. 2006....
Measles-virus-neutralizing antibodies in intravenous immunoglobulinsSusette Audet
Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD, USA
J Infect Dis 194:781-9. 2006..A reduction in mnAbs also correlated with the loss of either IgG1 and IgG3, possibly because of certain manufacturing procedures, or bivalent antibodies (i.e., intact IgG and F(ab')2), because of fragmentation...
International collaborative study to assess candidate reference preparations to control the level of anti-D in IVIG for use in Europe and the United StatesSusan J Thorpe
National Institute for Biological Standards and Control, Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3QG, UK
Biologicals 34:209-12. 2006....
HCV core antigen as an alternative to NAT to detect HCV viremiaChristina A Raker
Transfusion 44:307-8. 2004
