Beverly Word

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. ncbi Gender differences in gemcitabine (Gemzar) efficacy in cancer cells: effect of indole-3-carbinol
    Beverly D Lyn-Cook
    FDA National Center for Toxicological Research, Jefferson, Arkansas 72079, USA
    Anticancer Res 30:4907-13. 2010
  2. ncbi Age and gender affect DNMT3a and DNMT3b expression in human liver
    Yongmei Xiao
    Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, Jefferson, AR 72079, USA
    Cell Biol Toxicol 24:265-72. 2008
  3. ncbi Modulation of the constitutive activated STAT3 transcription factor in pancreatic cancer prevention: effects of indole-3-carbinol (I3C) and genistein
    Jian P Lian
    National Center for Toxicological Research, Jefferson, AR 72079, USA
    Anticancer Res 24:133-7. 2004
  4. ncbi Ethnic differences in DNA methyltransferases expression in patients with systemic lupus erythematosus
    Kenneth L Wiley
    FDA National Center for Toxicological Research, Jefferson, AR 72079, USA
    J Clin Immunol 33:342-8. 2013
  5. ncbi Enhanced efficacy of gemcitabine by indole-3-carbinol in pancreatic cell lines: the role of human equilibrative nucleoside transporter 1
    Honggang Wang
    Office of Regulatory Activities, FDA National Center for Toxicological Research, Jefferson, Arkansas 72079, U S A
    Anticancer Res 31:3171-80. 2011

Collaborators

  • Beverly D Lyn-Cook
  • Honggang Wang
  • Kenneth L Wiley
  • George Hammons
  • Aaron Haefele
  • Yongmei Xiao
  • Jian P Lian
  • Edward Treadwell
  • Kayihura Manigaba
  • Cornelius Davis
  • Sulma I Mohammed
  • Atena Starlard-Davenport
  • Skeetora Taylor
  • George J Hammons

Detail Information

Publications5

  1. ncbi Gender differences in gemcitabine (Gemzar) efficacy in cancer cells: effect of indole-3-carbinol
    Beverly D Lyn-Cook
    FDA National Center for Toxicological Research, Jefferson, Arkansas 72079, USA
    Anticancer Res 30:4907-13. 2010
    ..This study demonstrated the potential of I3C, a possible non-toxic hypomethylating agent, combined with the anticancer agent, gemcitabine, to be a powerful strategy for treating pancreatic cancer...
  2. ncbi Age and gender affect DNMT3a and DNMT3b expression in human liver
    Yongmei Xiao
    Division of Personalized Nutrition and Medicine, National Center for Toxicological Research, Jefferson, AR 72079, USA
    Cell Biol Toxicol 24:265-72. 2008
    ..The findings from this study suggest that ageing and gender may be important factors influencing DNA methylation status...
  3. ncbi Modulation of the constitutive activated STAT3 transcription factor in pancreatic cancer prevention: effects of indole-3-carbinol (I3C) and genistein
    Jian P Lian
    National Center for Toxicological Research, Jefferson, AR 72079, USA
    Anticancer Res 24:133-7. 2004
    ..CONCLUSION: Given its critical role in tumorigenesis, our results suggest that STAT3 activation provides an important and appropriate target for chemoprevention in pancreatic cancer treatment...
  4. ncbi Ethnic differences in DNA methyltransferases expression in patients with systemic lupus erythematosus
    Kenneth L Wiley
    FDA National Center for Toxicological Research, Jefferson, AR 72079, USA
    J Clin Immunol 33:342-8. 2013
    ..Furthermore, differential expression in one of the DNMTs was found in a subset of lupus patients on dehydroepiandrosterone (DHEA) therapy...
  5. ncbi Enhanced efficacy of gemcitabine by indole-3-carbinol in pancreatic cell lines: the role of human equilibrative nucleoside transporter 1
    Honggang Wang
    Office of Regulatory Activities, FDA National Center for Toxicological Research, Jefferson, Arkansas 72079, U S A
    Anticancer Res 31:3171-80. 2011
    ..This study demonstrates that up-regulation of hENT1 expression may be a novel mechanism involved in the additive effect of I3C and gemcitabine...