C A Wilson

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. ncbi Induction of ebolavirus cross-species immunity using retrovirus-like particles bearing the Ebola virus glycoprotein lacking the mucin-like domain
    Wu Ou
    Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Bldg, 29B, Room 5NN22, 8800 Rockville Pike, Bethesda, MD 20892, USA
    Virol J 9:32. 2012
  2. ncbi Identification of two distinct structural regions in a human porcine endogenous retrovirus receptor, HuPAR2, contributing to function for viral entry
    Katherine T Marcucci
    Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, 92037, USA
    Retrovirology 6:3. 2009
  3. ncbi Porcine endogenous retroviruses and xenotransplantation
    C A Wilson
    Division of Cellular and Gene Therapies, Gene Transfer and Immunogenicity Branch, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Cell Mol Life Sci 65:3399-412. 2008
  4. ncbi Substitution of a single amino acid residue is sufficient to allow the human amphotropic murine leukemia virus receptor to also function as a gibbon ape leukemia virus receptor
    M V Eiden
    Laboratory of Cell Biology, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    J Virol 70:1080-5. 1996
  5. ncbi Type C retrovirus released from porcine primary peripheral blood mononuclear cells infects human cells
    C A Wilson
    Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA
    J Virol 72:3082-7. 1998
  6. ncbi Simian sarcoma-associated virus fails to infect Chinese hamster cells despite the presence of functional gibbon ape leukemia virus receptors
    Y T Ting
    Laboratory of Cellular and Molecular Regulation, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    J Virol 72:9453-8. 1998
  7. ncbi Extended analysis of the in vitro tropism of porcine endogenous retrovirus
    C A Wilson
    Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA
    J Virol 74:49-56. 2000
  8. ncbi The Japanese feral mouse Pit1 and Pit2 homologs lack an acidic residue at position 550 but still function as gibbon ape leukemia virus receptors: implications for virus binding motif
    R D Schneiderman
    Laboratory of Cell Biology, National Institute of Mental Health, Bethesda, Maryland 20892 4068, USA
    J Virol 70:6982-6. 1996
  9. ncbi Detection and characterization of porcine endogenous retrovirus in porcine plasma and porcine factor VIII
    D M Takefman
    Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA
    J Virol 75:4551-7. 2001

Collaborators

  • Wu Ou
  • Katherine T Marcucci
  • M V Eiden
  • D M Takefman
  • K B Farrell
  • Takele Argaw
  • Daniel R Salomon
  • Y T Ting
  • R D Schneiderman
  • S Wong
  • K Peden
  • T Maudru
  • G J Chaudry

Detail Information

Publications9

  1. ncbi Induction of ebolavirus cross-species immunity using retrovirus-like particles bearing the Ebola virus glycoprotein lacking the mucin-like domain
    Wu Ou
    Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Bldg, 29B, Room 5NN22, 8800 Rockville Pike, Bethesda, MD 20892, USA
    Virol J 9:32. 2012
    ..We hypothesized that immunization with MLD-deleted GP1,2 (GPΔMLD) would induce cross-species immunity by making more conserved regions accessible to the immune system...
  2. ncbi Identification of two distinct structural regions in a human porcine endogenous retrovirus receptor, HuPAR2, contributing to function for viral entry
    Katherine T Marcucci
    Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, 92037, USA
    Retrovirology 6:3. 2009
    ....
  3. ncbi Porcine endogenous retroviruses and xenotransplantation
    C A Wilson
    Division of Cellular and Gene Therapies, Gene Transfer and Immunogenicity Branch, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Cell Mol Life Sci 65:3399-412. 2008
    ..However, in spite of the past 10 years of investigation, the actual risk for PERV infection, replication, and pathogenic outcome in human recipients of xenotransplantation products is still undefined. (Part of a multi-author review)...
  4. ncbi Substitution of a single amino acid residue is sufficient to allow the human amphotropic murine leukemia virus receptor to also function as a gibbon ape leukemia virus receptor
    M V Eiden
    Laboratory of Cell Biology, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    J Virol 70:1080-5. 1996
    ....
  5. ncbi Type C retrovirus released from porcine primary peripheral blood mononuclear cells infects human cells
    C A Wilson
    Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA
    J Virol 72:3082-7. 1998
    ..These findings demonstrate that the presence of endogenous viruses in source animals needs to be carefully considered when the infectious disease potential of xenotransplantation is being assessed...
  6. ncbi Simian sarcoma-associated virus fails to infect Chinese hamster cells despite the presence of functional gibbon ape leukemia virus receptors
    Y T Ting
    Laboratory of Cellular and Molecular Regulation, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    J Virol 72:9453-8. 1998
    ..This finding indicates that the region of the SSAV envelope protein responsible for restricting SSAV infection of E36 cells lies within its amino-terminal region...
  7. ncbi Extended analysis of the in vitro tropism of porcine endogenous retrovirus
    C A Wilson
    Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA
    J Virol 74:49-56. 2000
    ..Certain cell lines were permissive for efficient productive infection and spread. These results may prove useful in designing appropriate animal models to assess the in vivo infectivity properties of PERV...
  8. ncbi The Japanese feral mouse Pit1 and Pit2 homologs lack an acidic residue at position 550 but still function as gibbon ape leukemia virus receptors: implications for virus binding motif
    R D Schneiderman
    Laboratory of Cell Biology, National Institute of Mental Health, Bethesda, Maryland 20892 4068, USA
    J Virol 70:6982-6. 1996
    ..Further, the MolPit1 chimera was identical to Pit1 in efficiency, but the MolPit2 chimera proved substantially less efficient...
  9. ncbi Detection and characterization of porcine endogenous retrovirus in porcine plasma and porcine factor VIII
    D M Takefman
    Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA
    J Virol 75:4551-7. 2001
    ....