Research Topics
| Paul WhittakerSummaryAffiliation: Food and Drug Administration Country: USA Publications
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Detail Information
Publications
Evaluation of commercial kava extracts and kavalactone standards for mutagenicity and toxicity using the mammalian cell gene mutation assay in L5178Y mouse lymphoma cellsPaul Whittaker
Center for Food Safety and Applied Nutrition, Food and Drug Administration, 5100 Paint Branch Parkway, HFS 717, College Park, MD 20740 3835, USA
Food Chem Toxicol 46:168-74. 2008..Neither the kava samples nor the kavalactones induced a mutagenic response in the L5178Y mouse lymphoma mutation assay with the addition of human liver S9 activation...
Use of fatty acid profiles to identify food-borne bacterial pathogens and aerobic endospore-forming bacilliPaul Whittaker
Center for Food Safety and Applied Nutrition, Food and Drug Administration, 5100 Paint Branch Parkway, College Park, Maryland 20740 3835, USA
J Agric Food Chem 53:3735-42. 2005..anthracis and B. cereus spores but not in the vegetative cells. In summary, analysis of FAMEs from bacteria and spores can provide a sensitive procedure for the identification of food-borne pathogens...
Identification of six species in the new genus Cronobacter (Enterobacter sakazakii) from culture using gas chromatographic analysis of fatty acid methyl estersPaul Whittaker
U S Food and Drug Administration, Center for Food Safety and Applied Nutrition, Office of Regulatory Science, 5100 Paint Branch Pkwy, College Park, MD 20740 3835, USA
J AOAC Int 94:1581-4. 2011....
Differentiation of Enterobacter sakazakii from closely related Enterobacter and Citrobacter species using fatty acid profilesPaul Whittaker
Center for Food Safety and Applied Nutrition, U S Food and Drug Administration, College Park, Maryland 20740 3835, USA
J Agric Food Chem 55:4617-23. 2007..sakazakii strains from closely related Enterobacter and Citrobacter species...
Evaluating the use of fatty acid profiles to identify Francisella tularensisPaul Whittaker
U S Food and Drug Administration, Center for Food Safety and Applied Nutrition, 5100 Paint Branch Pkwy, College Park, MD 20740 3835, USA
J AOAC Int 90:465-9. 2007..tularensis. In summary, analysis of FAMEs from F. tularensis subspecies LVS and U112 grown on CHAB or Mueller-Hinton media, and using a rapid GC method can provide a sensitive procedure for identification of these organisms...
Evaluation of the butter flavoring chemical diacetyl and a fluorochemical paper additive for mutagenicity and toxicity using the mammalian cell gene mutation assay in L5178Y mouse lymphoma cellsPaul Whittaker
Center for Food Safety and Applied Nutrition, Food and Drug Administration, 5100 Paint Branch Parkway, HFS 717, College Park, MD 20740 3835, United States
Food Chem Toxicol 46:2928-33. 2008..The increase in the frequency of small colonies in the assay with diacetyl indicates that diacetyl causes damage to multiple loci on chromosome 11 in addition to functional loss of the thymidine kinase locus...
Mutagenicity of chromium picolinate and its components in Salmonella typhimurium and L5178Y mouse lymphoma cellsPaul Whittaker
Center for Food Safety and Applied Nutrition, Food and Drug Administration, College Park, MD 20740 3835, United States
Food Chem Toxicol 43:1619-25. 2005..Neither chromium picolinate nor chromium chloride induced a mutagenic response in S. typhimurium. However, in the L5178Y mouse lymphoma mutation assay, chromium picolinate induced mutagenic responses without and with the addition of S9...
Evaluating the use of fatty acid profiles to differentiate human pathogenic and nonpathogenic Listeria speciesPaul Whittaker
U S Food and Drug Administration, Center for Food Safety and Applied Nutrition, Office of Regulatory Science, 5100 Paint Branch Pkwy, College Park, MD 20740 3835, USA
J AOAC Int 95:1457-9. 2012..Analysis of FAMEs from Listeria strains grown on BHI agar by a GC-FID method is a sensitive procedure for identification of these organisms and differentiation between pathogenic and nonpathogenic species...
Cucurbitane-type triterpenoids from Momordica charantiaJun Ma
Office of Regulatory Science, Center for Food Safety and Applied Nutrition, U S Food and Drug Administration, College Park, MD 20740, USA
Planta Med 76:1758-61. 2010..Their structures were determined by chemical and spectroscopic methods. Momordicoside U (1) was evaluated for insulin secretion activity in an in vitro insulin secretion assay and displayed moderate activity...
Vibrio caribbeanicus sp. nov., isolated from the marine sponge Scleritoderma cyaneaMaria Hoffmann
US Food and Drug Administration, Paint Branch Parkway, College Park, MD 20740, USA
Int J Syst Evol Microbiol 62:1736-43. 2012..Collectively, these findings confirm that strain N384(T) represents a novel Vibrio species, for which the name Vibrio caribbeanicus sp. nov. is proposed, with the type strain N384(T) ( = ATCC BAA-2122(T) = DSM 23640(T))...
Dose-response effects of ectopic agouti protein on iron overload and age-associated aspects of the Avy/a obese mouse phenomeGeorge L Wolff
Division of Biochemical Toxicology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079 9502, USA
Peptides 26:1697-711. 2005....
Fatty acid composition and antioxidant properties of cold-pressed marionberry, boysenberry, red raspberry, and blueberry seed oilsJohn Parry
Department of Nutrition and Food Science, University of Maryland, College Park, MD 20742, USA
J Agric Food Chem 53:566-73. 2005..These data suggest that the cold-pressed berry seed oils may serve as potential dietary sources of tocopherols, carotenoids, and natural antioxidants...
