Yu Ping Wang

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. ncbi request reprint Metabolic activation of the tumorigenic pyrrolizidine alkaloid, retrorsine, leading to DNA adduct formation in vivo
    Yu Ping Wang
    National Center for Toxicological Research, Jefferson, AR 72079, USA
    Int J Environ Res Public Health 2:74-9. 2005
  2. ncbi request reprint Riddelliine N-oxide is a phytochemical and mammalian metabolite with genotoxic activity that is comparable to the parent pyrrolizidine alkaloid riddelliine
    Ming W Chou
    Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR 72079, USA
    Toxicol Lett 145:239-47. 2003
  3. ncbi request reprint Metabolic activation of the tumorigenic pyrrolizidine alkaloid, monocrotaline, leading to DNA adduct formation in vivo
    Yu Ping Wang
    Division of Biochemical Toxicology, National Center for Toxicological Research, 3900 NCTR Road, Jefferson, AR 72079, USA
    Cancer Lett 226:27-35. 2005
  4. ncbi request reprint Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid
    Yu Ping Wang
    Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR 72079, USA
    Toxicol Lett 155:411-20. 2005
  5. ncbi request reprint Effect of N,N-didesmethyltamoxifen upon DNA adduct formation by tamoxifen and alpha-hydroxytamoxifen
    Gonçalo Gamboa da Costa
    Centro de Quimica Estrutural, Instituto Superior Tecnico, Universidade Tecnica de Lisboa, Av Rovisco Pais, 1049 001 Lisboa, Portugal
    Cancer Lett 257:191-8. 2007

Collaborators

Detail Information

Publications5

  1. ncbi request reprint Metabolic activation of the tumorigenic pyrrolizidine alkaloid, retrorsine, leading to DNA adduct formation in vivo
    Yu Ping Wang
    National Center for Toxicological Research, Jefferson, AR 72079, USA
    Int J Environ Res Public Health 2:74-9. 2005
    ....
  2. ncbi request reprint Riddelliine N-oxide is a phytochemical and mammalian metabolite with genotoxic activity that is comparable to the parent pyrrolizidine alkaloid riddelliine
    Ming W Chou
    Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR 72079, USA
    Toxicol Lett 145:239-47. 2003
    ..Results presented in this paper indicate that riddelliine N-oxide, through its conversion to riddelliine, is also a potential genotoxic hepatocarcinogen...
  3. ncbi request reprint Metabolic activation of the tumorigenic pyrrolizidine alkaloid, monocrotaline, leading to DNA adduct formation in vivo
    Yu Ping Wang
    Division of Biochemical Toxicology, National Center for Toxicological Research, 3900 NCTR Road, Jefferson, AR 72079, USA
    Cancer Lett 226:27-35. 2005
    ....
  4. ncbi request reprint Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid
    Yu Ping Wang
    Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR 72079, USA
    Toxicol Lett 155:411-20. 2005
    ....
  5. ncbi request reprint Effect of N,N-didesmethyltamoxifen upon DNA adduct formation by tamoxifen and alpha-hydroxytamoxifen
    Gonçalo Gamboa da Costa
    Centro de Quimica Estrutural, Instituto Superior Tecnico, Universidade Tecnica de Lisboa, Av Rovisco Pais, 1049 001 Lisboa, Portugal
    Cancer Lett 257:191-8. 2007
    ..These results indicate that, with this experimental model, N,N-didesmethyltamoxifen does not impair the metabolism of tamoxifen to a reactive electrophile...