Research Topics
Genomes and Genes | Xue WangSummaryAffiliation: Food and Drug Administration Country: USA Publications
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Detail Information
Publications
c-FLIPL regulates PKC via AP-2 to inhibit Bax-mediated apoptosis induced by HIV-1 gp120 in Jurkat cellsXue Wang
Laboratory of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Building 29B, Rm 4NN16, 8800 Rockville Pike, Bethesda, MD, 20892, USA
Mol Cell Biochem 330:23-9. 2009..Collectively, these findings further corroborate the concept that gp120 plays an important role, via involvement of molecules such as c-FLIPL, in apoptotic cell death due to HIV-1 infection...
HIV-1 and HIV-2 infections induce autophagy in Jurkat and CD4+ T cellsXue Wang
Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, United States
Cell Signal 24:1414-9. 2012..The results indicate that HIV is able to induce the autophagic signaling pathway in HIV-infected host cells, which may be required for HIV infection-mediated apoptotic cell death...
Carbon monoxide inhibits Fas activating antibody-induced apoptosis in endothelial cellsXue Wang
Pulmonary and Critical Care Medicine, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA
Med Gas Res 1:8. 2011..abstract:..
Stability and infectivity of novel pandemic influenza A (H1N1) virus in blood-derived matrices under different storage conditionsXue Wang
Laboratory of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, CBER FDA, Bethesda, MD 20892, USA
BMC Infect Dis 11:354. 2011..Furthermore the effect of storage on virus stability and infectivity has not been well studied...
Molecules from apoptotic pathways modulate HIV-1 replication in Jurkat cellsXue Wang
Laboratory of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
Biochem Biophys Res Commun 414:20-4. 2011..We also discuss the effects of MAPK signaling pathways and apoptosis on HIV-1 replication...
Changes in the level of apoptosis-related proteins in Jurkat cells infected with HIV-1 versus HIV-2Xue Wang
Labaratory of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
Mol Cell Biochem 337:175-83. 2010....
CRF22_01A1 is involved in the emergence of new HIV-1 recombinants in CameroonJiangqin Zhao
Laboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 RockvillePike, Bethesda, MD 20892, USA
J Acquir Immune Defic Syndr 60:344-50. 2012..Our studies show that novel recombinants between CRF22_01A1 and other clades and recombinant forms may be emerging in Cameroon that could contribute to the future global diversity of HIV-1 in this region and worldwide...
Sensitive detection assays for influenza RNA do not reveal viremia in US blood donorsSusan L Stramer
American Red Cross Scientific Support Office, Gaithersburg, MD, USA
J Infect Dis 205:886-94. 2012..We present an assessment of the prevalence of seasonal and 2009 H1N1 influenza viremia (via RNA testing) in blood donor populations using multiple sensitive detection assays...
Rapid detection and differentiation of swine-origin influenza A virus (H1N1/2009) from other seasonal influenza A virusesJiangqin Zhao
Laboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
Viruses 4:3012-9. 2012..This new method may be useful for simultaneous detection and subtyping of influenza A viruses and can be rapidly modified to detect other emerging influenza strains in public health settings...
Absence of detectable xenotropic murine leukemia virus-related virus in plasma or peripheral blood mononuclear cells of human immunodeficiency virus Type 1-infected blood donors or individuals in AfricaShixing Tang
Laboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA
Transfusion 51:463-8. 2011....
Multiplexed, rapid detection of H5N1 using a PCR-free nanoparticle-based genomic microarray assayJiangqin Zhao
Lab of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
BMC Biotechnol 10:74. 2010....
Viremia associated with fatal outcomes in ferrets infected with avian H5N1 influenza virusXue Wang
Lab of Molecular Virology, Division of Emerging and Transfusion Transmitted Diseases, Food and Drug Administration, Bethesda, Maryland, USA
PLoS ONE 5:e12099. 2010..Our observations further substantiate pathogenicity of H5N1 and further indicate that viremia may be a bio-marker for fatal outcomes in H5N1 infection...
Characterization of immune responses to capsid protein p24 of human immunodeficiency virus type 1 and implications for detectionShixing Tang
Lab of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, USA
Clin Vaccine Immunol 17:1244-51. 2010..The data provide the foundation for development and refinement of new assays for improved p24 antigen testing as future tools for rapid and accurate diagnosis as part of early intervention strategies and estimations of incidence...
