Richard I Walker

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. ncbi request reprint Considerations for development of whole cell bacterial vaccines to prevent diarrheal diseases in children in developing countries
    Richard I Walker
    Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike HFM 425, Rockville, MD 20851 1448, USA
    Vaccine 23:3369-85. 2005
  2. ncbi request reprint Enteric vaccines for pediatric use. Workshop summary
    Richard I Walker
    Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike HFM 425, Rockville, MD 20851 1448, USA
    Vaccine 23:5432-9. 2005
  3. ncbi request reprint New vaccines against enteric bacteria for children in less developed countries
    Richard I Walker
    Division of Bacterial, Parasitic and Allergenic Products, US Food and Drug Administration, 1401 Rockville Pike HFM 425, Rockville, MD20651 1448, USA
    Expert Rev Vaccines 4:807-12. 2005
  4. ncbi request reprint Analysis of strategies to successfully vaccinate infants in developing countries against enterotoxigenic E. coli (ETEC) disease
    Richard I Walker
    Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike, Rockville, MD 20851 1448, USA
    Vaccine 25:2545-66. 2007
  5. ncbi request reprint Vaccine potential for inactivated shigellae
    Manuel Osorio
    Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike, Rockville, MD 20852 1448, United States
    Vaccine 25:1581-92. 2007
  6. ncbi request reprint Prevention of disease in ferrets fed an inactivated whole cell Campylobacter jejuni vaccine
    Donald H Burr
    Food and Drug Administration, Laurel, MD 20708, USA
    Vaccine 23:4315-21. 2005
  7. ncbi request reprint B cell responses in gastric antrum and duodenum following oral inactivated Helicobacter pylori whole cell (HWC) vaccine and LT(R192G) in H pylori seronegative individuals
    Genevieve A Losonsky
    Department of Pediatrics, Baltimore, MD 21201, USA
    Vaccine 21:562-5. 2003
  8. pmc In vivo phase variation and serologic response to lipooligosaccharide of Campylobacter jejuni in experimental human infection
    Martina M Prendergast
    Department of Microbiology, National University of Ireland, Galway, Ireland
    Infect Immun 72:916-22. 2004
  9. ncbi request reprint Meeting summary: possibilities for active and passive vaccination against opportunistic infections
    Richard I Walker
    Vaccine 22:801-4. 2004

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Considerations for development of whole cell bacterial vaccines to prevent diarrheal diseases in children in developing countries
    Richard I Walker
    Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike HFM 425, Rockville, MD 20851 1448, USA
    Vaccine 23:3369-85. 2005
    ....
  2. ncbi request reprint Enteric vaccines for pediatric use. Workshop summary
    Richard I Walker
    Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike HFM 425, Rockville, MD 20851 1448, USA
    Vaccine 23:5432-9. 2005
    ..No insurmountable roadblocks to progress in this area were noted, and the possibility currently exists that properly supported efforts will enable the realization of enteric vaccines for pediatric use...
  3. ncbi request reprint New vaccines against enteric bacteria for children in less developed countries
    Richard I Walker
    Division of Bacterial, Parasitic and Allergenic Products, US Food and Drug Administration, 1401 Rockville Pike HFM 425, Rockville, MD20651 1448, USA
    Expert Rev Vaccines 4:807-12. 2005
    ..These candidate vaccines potentially provide a relatively simple intervention which could, if implemented, reduce the impact of these diseases upon the life and productivity of children...
  4. ncbi request reprint Analysis of strategies to successfully vaccinate infants in developing countries against enterotoxigenic E. coli (ETEC) disease
    Richard I Walker
    Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike, Rockville, MD 20851 1448, USA
    Vaccine 25:2545-66. 2007
    ..However, a Product Development Partnership to overcome this hurdle could accelerate the time lines towards when control of ETEC disease in DCs is substantially closer...
  5. ncbi request reprint Vaccine potential for inactivated shigellae
    Manuel Osorio
    Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike, Rockville, MD 20852 1448, United States
    Vaccine 25:1581-92. 2007
    ..These in vivo and in vitro data indicate that inactivated shigellae retain the ability to interact effectively with key antigen presenting cells and induce protective immune responses in mice...
  6. ncbi request reprint Prevention of disease in ferrets fed an inactivated whole cell Campylobacter jejuni vaccine
    Donald H Burr
    Food and Drug Administration, Laurel, MD 20708, USA
    Vaccine 23:4315-21. 2005
    ..They also show that protection and serum IgG responses do not depend upon the use of the mucosal adjuvant and that cross protection among some of the major serotypes of Campylobacter responsible for human disease is possible...
  7. ncbi request reprint B cell responses in gastric antrum and duodenum following oral inactivated Helicobacter pylori whole cell (HWC) vaccine and LT(R192G) in H pylori seronegative individuals
    Genevieve A Losonsky
    Department of Pediatrics, Baltimore, MD 21201, USA
    Vaccine 21:562-5. 2003
    ..01 and P=0.05, respectively). These results provide the first evidence that specific gastric B cell responses can be induced in HP-non-infected individuals following oral immunization...
  8. pmc In vivo phase variation and serologic response to lipooligosaccharide of Campylobacter jejuni in experimental human infection
    Martina M Prendergast
    Department of Microbiology, National University of Ireland, Galway, Ireland
    Infect Immun 72:916-22. 2004
    ..jejuni or following administration of a killed C. jejuni whole-cell oral vaccine, although LOS phase variation occurred...
  9. ncbi request reprint Meeting summary: possibilities for active and passive vaccination against opportunistic infections
    Richard I Walker
    Vaccine 22:801-4. 2004