Jaroslav G Vostal

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. ncbi request reprint Efficacy evaluation of current and future platelet transfusion products
    Jaroslav G Vostal
    Laboratory of Cellular Hematology, Division of Hematology, OBRR, Center for Biologics Evaluation and Research, FDA, 1401 Rockville Pike, Rockville, MD 20852 1448, USA
    J Trauma 60:S78-82. 2006
  2. doi request reprint Activation of platelet protein kinase C by ultraviolet light B mediates platelet transfusion-related acute lung injury in a two-event animal model
    Li Zhi
    Laboratory of Cellular Hematology, Division of Hematology, OBRR, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA
    Transfusion 53:722-31. 2013
  3. ncbi request reprint Elevated circulating endothelial membrane microparticles in paroxysmal nocturnal haemoglobinuria
    Jan Simak
    Laboratory of Cellular Hematology, Division of Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD, USA
    Br J Haematol 125:804-13. 2004
  4. doi request reprint Temperature cycling improves in vivo recovery of cold-stored human platelets in a mouse model of transfusion
    Fei Xu
    Laboratory of Cellular Hematology, Center for Biologics Evaluation and Research, FDA, Bethesda, Maryland 20852 1448, USA
    Transfusion 53:1178-86. 2013
  5. pmc Host platelets and, in part, neutrophils mediate lung accumulation of transfused UVB-irradiated human platelets in a mouse model of acute lung injury
    Xuan Chi
    Laboratory of Cellular Hematology, Division of Hematology, OBRR, Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, Maryland, United States of America
    PLoS ONE 7:e44829. 2012
  6. pmc Release of annexin V-binding membrane microparticles from cultured human umbilical vein endothelial cells after treatment with camptothecin
    Jan Simak
    Laboratory of Cellular Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    BMC Cell Biol 3:11. 2002
  7. ncbi request reprint Activated platelets of patients with paroxysmal nocturnal hemoglobinuria express cellular prion protein
    Karel Holada
    Laboratory of Cellular Hematology, Division of Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Blood 100:341-3. 2002
  8. doi request reprint Current and future cellular transfusion products
    Monique P Gelderman
    Laboratory of Cellular Hematology, Division of Hematology, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike, Rockville, MD 20852 1448, USA
    Clin Lab Med 30:443-52. 2010
  9. ncbi request reprint In vivo recovery of human platelets in severe combined immunodeficient mice as a measure of platelet damage
    John T Piper
    Laboratory of Cellular Hematology, Division of Hematology, Office of Blood Research and Review, Center for Biologics Evaluation and Research, United States Food and Drug Administration, 1401 Rockville Pike, Rockville, MD 20852, USA
    Transfusion 47:1540-9. 2007
  10. doi request reprint Ultraviolet B light-exposed human platelets mediate acute lung injury in a two-event mouse model of transfusion
    Monique P Gelderman
    Laboratory of Cellular Hematology, Division of Hematology, OBRR, Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, Maryland 20892, USA
    Transfusion 51:2343-57. 2011

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Efficacy evaluation of current and future platelet transfusion products
    Jaroslav G Vostal
    Laboratory of Cellular Hematology, Division of Hematology, OBRR, Center for Biologics Evaluation and Research, FDA, 1401 Rockville Pike, Rockville, MD 20852 1448, USA
    J Trauma 60:S78-82. 2006
  2. doi request reprint Activation of platelet protein kinase C by ultraviolet light B mediates platelet transfusion-related acute lung injury in a two-event animal model
    Li Zhi
    Laboratory of Cellular Hematology, Division of Hematology, OBRR, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA
    Transfusion 53:722-31. 2013
    ..We have now identified changes in HPs induced by UVB light and responses of the recipient animal that mediate the mTRALI...
  3. ncbi request reprint Elevated circulating endothelial membrane microparticles in paroxysmal nocturnal haemoglobinuria
    Jan Simak
    Laboratory of Cellular Hematology, Division of Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD, USA
    Br J Haematol 125:804-13. 2004
    ..Analysis of circulating ECMP appears promising to provide useful information on the status of the vascular endothelium in PNH and SCD...
  4. doi request reprint Temperature cycling improves in vivo recovery of cold-stored human platelets in a mouse model of transfusion
    Fei Xu
    Laboratory of Cellular Hematology, Center for Biologics Evaluation and Research, FDA, Bethesda, Maryland 20852 1448, USA
    Transfusion 53:1178-86. 2013
    ..We cycled storage temperature between 4 and 37°C to preserve PLT function and reduce bacterial growth...
  5. pmc Host platelets and, in part, neutrophils mediate lung accumulation of transfused UVB-irradiated human platelets in a mouse model of acute lung injury
    Xuan Chi
    Laboratory of Cellular Hematology, Division of Hematology, OBRR, Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, Maryland, United States of America
    PLoS ONE 7:e44829. 2012
    ..Neutrophils also recruited a small percentage of platelets to the lung. These findings may help develop therapeutic strategies for ALI which could potentially result from transfusion of UV illuminated platelets...
  6. pmc Release of annexin V-binding membrane microparticles from cultured human umbilical vein endothelial cells after treatment with camptothecin
    Jan Simak
    Laboratory of Cellular Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    BMC Cell Biol 3:11. 2002
    ..We used flow cytometry to study the MP-release from cultured human umbilical vein endothelial cells (HUVEC) stimulated by various agonists. MP-release by a topoisomerase I inhibitor camptothecin has been studied in detail...
  7. ncbi request reprint Activated platelets of patients with paroxysmal nocturnal hemoglobinuria express cellular prion protein
    Karel Holada
    Laboratory of Cellular Hematology, Division of Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Blood 100:341-3. 2002
    ..Our results indicate that in the absence of GPI anchor, PrPc can be expressed intracellularly and up-regulated on the platelet membrane, likely in a transmembrane form with the C-terminal part of the molecule inserted into the cytoplasm...
  8. doi request reprint Current and future cellular transfusion products
    Monique P Gelderman
    Laboratory of Cellular Hematology, Division of Hematology, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike, Rockville, MD 20852 1448, USA
    Clin Lab Med 30:443-52. 2010
    ..This article reviews the literature and discusses the current and future state of cellular transfusion products...
  9. ncbi request reprint In vivo recovery of human platelets in severe combined immunodeficient mice as a measure of platelet damage
    John T Piper
    Laboratory of Cellular Hematology, Division of Hematology, Office of Blood Research and Review, Center for Biologics Evaluation and Research, United States Food and Drug Administration, 1401 Rockville Pike, Rockville, MD 20852, USA
    Transfusion 47:1540-9. 2007
    ..The severe combined immunodeficient (SCID) mice allowed prolonged circulation of human PLTs and were used to detect differences in recovery and survival between chemically damaged, aged PLTs, or normal PLTs...
  10. doi request reprint Ultraviolet B light-exposed human platelets mediate acute lung injury in a two-event mouse model of transfusion
    Monique P Gelderman
    Laboratory of Cellular Hematology, Division of Hematology, OBRR, Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, Maryland 20892, USA
    Transfusion 51:2343-57. 2011
    ..Clinical trials of UV-treated PLTs in patients with thrombocytopenia generated controversy regarding association of these cells with respiratory distress. We evaluated whether UVB PLTs could mediate ALI in an animal model of ALI...
  11. doi request reprint Rejuvenation improves roller pump-induced physical stress resistance of fresh and stored red blood cells
    Monique P Gelderman
    Laboratory of Cellular Hematology, Division of Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, Maryland 20852 1448, USA
    Transfusion 51:1096-104. 2011
    ..Similar studies were also done on cardiac surgery patients who were placed on cardiac bypass pumps. It is possible that stored RBCs are more fragile and could be more easily damaged by these pumps, thus leading to additional morbidity...
  12. doi request reprint Human cellular prion protein interacts directly with clusterin protein
    Fei Xu
    Division of Hematology, Office of Blood Research and Review, Center for Biologics Evaluation and Research, United States Food and Drug Administration, Bethesda, MD, USA
    Biochim Biophys Acta 1782:615-20. 2008
    ..These findings provide new insights into the molecular mechanisms of interaction between prion and clusterin protein and contribute to the understanding of prion protein's physiological function...
  13. ncbi request reprint Cellular prion protein is expressed on endothelial cells and is released during apoptosis on membrane microparticles found in human plasma
    Jan Simak
    Laboratory of Cellular Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 28092, USA
    Transfusion 42:334-42. 2002
    ..In orally infected animals, PrPsc accumulates in intestinal endothelial cells. In blood, two thirds of PrPc resides in plasma, but its source is not known...
  14. pmc Scrapie infectivity in hamster blood is not associated with platelets
    Karel Holada
    Laboratory of Cellular Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA
    J Virol 76:4649-50. 2002
    ..This result indicates that platelets are not the source of blood-borne infectivity in transmissible spongiform encephalopathy-infected hamsters...
  15. ncbi request reprint Cold temperatures reduce the sensitivity of stored platelets to disaggregating agents
    Traci Heath Mondoro
    Laboratory of Cellular Hematology, Center for Biologics Evaluation and Research, FDA, Bethesda, MD 20892, USA
    Platelets 13:11-20. 2002
    ..Differences between aggregation and disaggregation responses of cold- and room temperature-stored platelets suggest that cold-stored platelets may have different mechanisms to stabilize platelet aggregates during their formation...
  16. ncbi request reprint Adenoviral vectors do not induce, inhibit, or potentiate human platelet aggregation
    Thomas L Eggerman
    Division of Cellular and Gene Therapy, Office of Therapeutics Research and Review, FDA, Bethesda, MD 20892, USA
    Hum Gene Ther 13:125-8. 2002
    ..These results suggest that the adenovirus-associated thrombocytopenia observed in vivo is independent of a direct effect of the virus on platelet aggregation...
  17. ncbi request reprint Toxicity of a first-generation adenoviral vector in rhesus macaques
    Jay N Lozier
    National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA
    Hum Gene Ther 13:113-24. 2002
    ..The rhesus macaque may be a useful animal model in which to evaluate mechanisms of adenovirus toxicities that have been encountered during clinical gene therapy trials...
  18. ncbi request reprint Expression of cellular prion protein on platelets from patients with gray platelet or Hermansky-Pudlak syndrome and the protein's association with alpha-granules
    Karel Holada
    Institute of Immunology and Microbiology, 1st Faculty of Medicine Charles University Prague, Studnickova 7, 128 20 Prague 2, Czech Republic
    Haematologica 91:1126-9. 2006
    ..Our results warrant further studies on the role of platelet PrPc in the transmission of prion diseases by blood transfusion...
  19. ncbi request reprint Endogenous osteonectin/SPARC/BM-40 expression inhibits MDA-MB-231 breast cancer cell metastasis
    Jennifer E Koblinski
    Craniofacial Developmental Biology and Regeneration Branch and Gene Therapy and Therapeutics Branch, National Institute of Dental and Craniofacial Research, NIH, Bethesda, Maryland 20892 4370, USA
    Cancer Res 65:7370-7. 2005
    ..These studies suggest that high endogenous expression of osteonectin in breast cancer cells may reduce metastasis via reduced invasive activity and reduced tumor cell-platelet aggregation...
  20. ncbi request reprint CD34+ cells from paroxysmal nocturnal hemoglobinuria (PNH) patients are deficient in surface expression of cellular prion protein (PrPc)
    Antonio M Risitano
    Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA
    Exp Hematol 31:65-72. 2003
    ..Conversely, PrP(c) is a good model to elucidate the fate of GPI-AP in PIG-A-deficient cells...