Research Topics
Genomes and GenesSpecies | John Terrig ThomasSummaryAffiliation: Food and Drug Administration Country: USA Publications
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Detail Information
Publications
CDMP1/GDF5 has specific processing requirements that restrict its action to joint surfacesJ Terrig Thomas
Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, United States Food and Drug Administration, Bethesda, Maryland 20892, USA
J Biol Chem 281:26725-33. 2006..Taken together, these observations provide a plausible mechanism for local action of CDMP1/GDF5 consistent with requirements imposed by current models of pattern formation in the developing limb...
Vg1 has specific processing requirements that restrict its action to body axis patterning centersJohn Terrig Thomas
Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, U S Food and Drug Administration, Bethesda, MD 20892, USA
Dev Biol 310:129-39. 2007..Taken together, these observations provide a plausible mechanism for local action of Vg1 consistent with requirements imposed by current models of pattern formation in the developing body axis...
Xenopus SMOC-1 Inhibits bone morphogenetic protein signaling downstream of receptor binding and is essential for postgastrulation development in XenopusJ Terrig Thomas
Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, United States Food and Drug Administration, Bethesda, Maryland 20892, USA
J Biol Chem 284:18994-9005. 2009..These findings provide a direct link between the extracellular matrix-associated protein SMOC and a signaling pathway of general importance in anatomic patterning and cell or tissue fate specification...
A homolog of Subtilisin-like Proprotein Convertase 7 is essential to anterior neural development in XenopusSema Senturker
Division of Cellular and Gene Therapies, Center for Biologics, Evaluation and Research, United States Food and Drug Administration, Bethesda, Maryland, United States of America
PLoS ONE 7:e39380. 2012..Other SPCs are known to be required during embryonic development but corresponding data regarding SPC7 have not been reported previously...
