J E Slater

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. ncbi request reprint Murine B-cell and T-cell epitopes of the allergen Hev b 5 from natural rubber latex
    J E Slater
    Center for Molecular Mechanisms of Disease Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    Mol Immunol 36:135-43. 1999
  2. ncbi request reprint Characterization of allergen extracts
    J E Slater
    Laboratory of Immunobiochemistry, Division of Bacterial Parasitic and Allergenic Products, Office of Vaccines Regulation and Research, CBER USFDA, Bethesda, MD, USA
    Dev Biol (Basel) 122:145-52. 2005
  3. ncbi request reprint Competition enzyme-linked immunosorbant assay (ELISA) can be a sensitive method for the specific detection of small quantities of allergen in a complex mixture
    E Dobrovolskaia
    Center for Biologics Evaluation and Research, US Food and Drug Administration, Bethesda, MD 20852, USA
    Clin Exp Allergy 36:525-30. 2006
  4. ncbi request reprint Biological potency of German cockroach allergen extracts determined in an inner city population
    J E Slater
    Center for Biologics Evaluation and Research, U S Food and Drug Administration, Bethesda, MD, USA
    Clin Exp Allergy 37:1033-9. 2007
  5. ncbi request reprint Exploiting the avian immunoglobulin system to simplify the generation of recombinant antibodies to allergenic proteins
    W J J Finlay
    Center for Biologics Evaluation and Research, US Food and Drug Administration, Bethesda, MD 20892, USA
    Clin Exp Allergy 35:1040-8. 2005
  6. ncbi request reprint Characterization and comparison of commercially available German and American cockroach allergen extracts
    M L Patterson
    Laboratory of Immunobiochemistry, Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, U S Food and Drug Administration, Bethesda 20852, USA
    Clin Exp Allergy 32:721-7. 2002
  7. ncbi request reprint Specific monoclonal antibodies and human immunoglobulin E show that Hev b 5 is an abundant allergen in high protein powdered latex gloves
    M F Sutherland
    Department of Allergy, Asthma and Clinical Immunology, The Alfred Hospital and Monash University, Victoria, Australia
    Clin Exp Allergy 32:583-9. 2002

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Murine B-cell and T-cell epitopes of the allergen Hev b 5 from natural rubber latex
    J E Slater
    Center for Molecular Mechanisms of Disease Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    Mol Immunol 36:135-43. 1999
    ..Since they may contain major T-cell epitopes but do not exhibit significant antibody binding, peptide regions 38-48 and 75-101 are candidates for specific immunotherapy to Hev b 5 in the BALB/c mouse model...
  2. ncbi request reprint Characterization of allergen extracts
    J E Slater
    Laboratory of Immunobiochemistry, Division of Bacterial Parasitic and Allergenic Products, Office of Vaccines Regulation and Research, CBER USFDA, Bethesda, MD, USA
    Dev Biol (Basel) 122:145-52. 2005
    ..The surrogate tests differ for different extracts. National reference standards to which manufactured lots are compared are maintained at FDA/CBER. Allergen standardization has facilitated the establishment of data-driven release limits...
  3. ncbi request reprint Competition enzyme-linked immunosorbant assay (ELISA) can be a sensitive method for the specific detection of small quantities of allergen in a complex mixture
    E Dobrovolskaia
    Center for Biologics Evaluation and Research, US Food and Drug Administration, Bethesda, MD 20852, USA
    Clin Exp Allergy 36:525-30. 2006
    ..This study was designed to determine the sensitivity of the competition ELISA to detect the specific loss of Bla g 1 and Bla g 2 in cockroach extracts...
  4. ncbi request reprint Biological potency of German cockroach allergen extracts determined in an inner city population
    J E Slater
    Center for Biologics Evaluation and Research, U S Food and Drug Administration, Bethesda, MD, USA
    Clin Exp Allergy 37:1033-9. 2007
    ..To perform valid studies on the diagnosis and treatment of cockroach allergy, biological potencies of test extracts need to be established, and a surrogate in vitro test for biological potency should be chosen...
  5. ncbi request reprint Exploiting the avian immunoglobulin system to simplify the generation of recombinant antibodies to allergenic proteins
    W J J Finlay
    Center for Biologics Evaluation and Research, US Food and Drug Administration, Bethesda, MD 20892, USA
    Clin Exp Allergy 35:1040-8. 2005
    ..Therefore, we have examined recombinant antibody development by phage-display against single allergens and protein mixtures...
  6. ncbi request reprint Characterization and comparison of commercially available German and American cockroach allergen extracts
    M L Patterson
    Laboratory of Immunobiochemistry, Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, U S Food and Drug Administration, Bethesda 20852, USA
    Clin Exp Allergy 32:721-7. 2002
    ..In this study we examine the variability among unstandardized cockroach allergen extracts...
  7. ncbi request reprint Specific monoclonal antibodies and human immunoglobulin E show that Hev b 5 is an abundant allergen in high protein powdered latex gloves
    M F Sutherland
    Department of Allergy, Asthma and Clinical Immunology, The Alfred Hospital and Monash University, Victoria, Australia
    Clin Exp Allergy 32:583-9. 2002
    ..Moreover, standardized immunological assays for the detection of Hev b 5 are currently lacking and may have important implications for both allergen avoidance and diagnosis in latex allergy...