J E Slater

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. ncbi The US Food and Drug Administration review of the safety and effectiveness of nonstandardized allergen extracts
    Jay E Slater
    US Food and Drug Administration, Rockville, MD, USA
    J Allergy Clin Immunol 129:1014-9. 2012
  2. ncbi Biological potency of German cockroach allergen extracts determined in an inner city population
    J E Slater
    Center for Biologics Evaluation and Research, U S Food and Drug Administration, Bethesda, MD, USA
    Clin Exp Allergy 37:1033-9. 2007
  3. ncbi Competition enzyme-linked immunosorbant assay (ELISA) can be a sensitive method for the specific detection of small quantities of allergen in a complex mixture
    E Dobrovolskaia
    Center for Biologics Evaluation and Research, US Food and Drug Administration, Bethesda, MD 20852, USA
    Clin Exp Allergy 36:525-30. 2006
  4. ncbi Characterization of allergen extracts
    J E Slater
    Laboratory of Immunobiochemistry, Division of Bacterial Parasitic and Allergenic Products, Office of Vaccines Regulation and Research, CBER USFDA, Bethesda, MD, USA
    Dev Biol (Basel) 122:145-52. 2005
  5. ncbi Characterization and comparison of commercially available German and American cockroach allergen extracts
    M L Patterson
    Laboratory of Immunobiochemistry, Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, U S Food and Drug Administration, Bethesda 20852, USA
    Clin Exp Allergy 32:721-7. 2002
  6. ncbi Exploiting the avian immunoglobulin system to simplify the generation of recombinant antibodies to allergenic proteins
    W J J Finlay
    Center for Biologics Evaluation and Research, US Food and Drug Administration, Bethesda, MD 20892, USA
    Clin Exp Allergy 35:1040-8. 2005
  7. ncbi Specific monoclonal antibodies and human immunoglobulin E show that Hev b 5 is an abundant allergen in high protein powdered latex gloves
    M F Sutherland
    Department of Allergy, Asthma and Clinical Immunology, The Alfred Hospital and Monash University, Victoria, Australia
    Clin Exp Allergy 32:583-9. 2002

Collaborators

Detail Information

Publications7

  1. ncbi The US Food and Drug Administration review of the safety and effectiveness of nonstandardized allergen extracts
    Jay E Slater
    US Food and Drug Administration, Rockville, MD, USA
    J Allergy Clin Immunol 129:1014-9. 2012
    ..Two external panels deliberated, the first from 1974-1979 and the second from 1982-1983...
  2. ncbi Biological potency of German cockroach allergen extracts determined in an inner city population
    J E Slater
    Center for Biologics Evaluation and Research, U S Food and Drug Administration, Bethesda, MD, USA
    Clin Exp Allergy 37:1033-9. 2007
    ..To perform valid studies on the diagnosis and treatment of cockroach allergy, biological potencies of test extracts need to be established, and a surrogate in vitro test for biological potency should be chosen...
  3. ncbi Competition enzyme-linked immunosorbant assay (ELISA) can be a sensitive method for the specific detection of small quantities of allergen in a complex mixture
    E Dobrovolskaia
    Center for Biologics Evaluation and Research, US Food and Drug Administration, Bethesda, MD 20852, USA
    Clin Exp Allergy 36:525-30. 2006
    ..CONCLUSION: The competition ELISA can be highly sensitive to compositional differences in complex allergen mixtures, even when the specific detecting antibody is present in relatively small amounts...
  4. ncbi Characterization of allergen extracts
    J E Slater
    Laboratory of Immunobiochemistry, Division of Bacterial Parasitic and Allergenic Products, Office of Vaccines Regulation and Research, CBER USFDA, Bethesda, MD, USA
    Dev Biol (Basel) 122:145-52. 2005
    ..The surrogate tests differ for different extracts. National reference standards to which manufactured lots are compared are maintained at FDA/CBER. Allergen standardization has facilitated the establishment of data-driven release limits...
  5. ncbi Characterization and comparison of commercially available German and American cockroach allergen extracts
    M L Patterson
    Laboratory of Immunobiochemistry, Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, U S Food and Drug Administration, Bethesda 20852, USA
    Clin Exp Allergy 32:721-7. 2002
    ..In this study we examine the variability among unstandardized cockroach allergen extracts...
  6. ncbi Exploiting the avian immunoglobulin system to simplify the generation of recombinant antibodies to allergenic proteins
    W J J Finlay
    Center for Biologics Evaluation and Research, US Food and Drug Administration, Bethesda, MD 20892, USA
    Clin Exp Allergy 35:1040-8. 2005
    ..The resulting antibody fragments are of demonstrable use in allergen identification and quantification, in comparison with standard immunoassays...
  7. ncbi Specific monoclonal antibodies and human immunoglobulin E show that Hev b 5 is an abundant allergen in high protein powdered latex gloves
    M F Sutherland
    Department of Allergy, Asthma and Clinical Immunology, The Alfred Hospital and Monash University, Victoria, Australia
    Clin Exp Allergy 32:583-9. 2002
    ..This may explain the observed higher frequency of sensitization to this allergen in HCWs...