Erica Silberstein

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. pmc The interaction of hepatitis A virus (HAV) with soluble forms of its cellular receptor 1 (HAVCR1) share the physiological requirements of infectivity in cell culture
    Erica Silberstein
    Laboratory of Hepatitis and Related Emerging Agents, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, USA
    Virol J 6:175. 2009
  2. pmc Immunoglobulin A (IgA) is a natural ligand of hepatitis A virus cellular receptor 1 (HAVCR1), and the association of IgA with HAVCR1 enhances virus-receptor interactions
    Cecilia Tami
    Laboratory of Hepatitis and Related Emerging Agents, CBER, Food and Drug Administration, Bethesda, MD 20892, USA
    J Virol 81:3437-46. 2007
  3. pmc Alteration of hepatitis A virus (HAV) particles by a soluble form of HAV cellular receptor 1 containing the immunoglobin-and mucin-like regions
    Erica Silberstein
    Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA
    J Virol 77:8765-74. 2003
  4. ncbi request reprint Innate immunity and hepatitis C virus: eluding the host cell defense
    Deborah R Taylor
    Laboratory of Hepatitis and Related Emerging Agents, Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, CBER FDA, Bethesda, MD 20892, USA
    Front Biosci (Landmark Ed) 14:4950-61. 2009
  5. pmc Persistent growth of a human plasma-derived hepatitis C virus genotype 1b isolate in cell culture
    Erica Silberstein
    Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA
    PLoS Pathog 6:e1000910. 2010
  6. pmc Overcoming hurdles in hepatitis C virus research: efficient production of infectious virus in cell culture
    Erica Silberstein
    Laboratory of Hepatitis and Related Emerging Agents, Center for Biologics Evaluation and Research, US Food and Drug Administration
    Int J Biomed Sci 4:82-8. 2008

Collaborators

Detail Information

Publications6

  1. pmc The interaction of hepatitis A virus (HAV) with soluble forms of its cellular receptor 1 (HAVCR1) share the physiological requirements of infectivity in cell culture
    Erica Silberstein
    Laboratory of Hepatitis and Related Emerging Agents, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, USA
    Virol J 6:175. 2009
    ..Here, we used HAV soluble receptor neutralization and alteration assays to study the requirements of the HAV-HAVCR1 interaction and to determine whether HAVCR1 is also a receptor for wt HAV...
  2. pmc Immunoglobulin A (IgA) is a natural ligand of hepatitis A virus cellular receptor 1 (HAVCR1), and the association of IgA with HAVCR1 enhances virus-receptor interactions
    Cecilia Tami
    Laboratory of Hepatitis and Related Emerging Agents, CBER, Food and Drug Administration, Bethesda, MD 20892, USA
    J Virol 81:3437-46. 2007
    ..IgA enhanced significantly the neutralization of HAV by HAVCR1/TIM1 Fc. Our results indicate that IgA1lambda is a specific ligand of HAVCR1/TIM1 and that their association has a synergistic effect in virus-receptor interactions...
  3. pmc Alteration of hepatitis A virus (HAV) particles by a soluble form of HAV cellular receptor 1 containing the immunoglobin-and mucin-like regions
    Erica Silberstein
    Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA
    J Virol 77:8765-74. 2003
    ..Quantitative PCR analysis showed that the 100- to 125S particles contained viral RNA. These results indicate that D1 and the mucin-like region of havcr-1 are required to induce conformational changes leading to HAV uncoating...
  4. ncbi request reprint Innate immunity and hepatitis C virus: eluding the host cell defense
    Deborah R Taylor
    Laboratory of Hepatitis and Related Emerging Agents, Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, CBER FDA, Bethesda, MD 20892, USA
    Front Biosci (Landmark Ed) 14:4950-61. 2009
    ..Here we review the different ways that HCV evades the immune response elicited by IFN...
  5. pmc Persistent growth of a human plasma-derived hepatitis C virus genotype 1b isolate in cell culture
    Erica Silberstein
    Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA
    PLoS Pathog 6:e1000910. 2010
    ..This virus constitutes a novel tool for the study of one of the most relevant strains of HCV, genotype 1b, which will now be available for HCV life cycle research and useful for the development of new therapeutics...
  6. pmc Overcoming hurdles in hepatitis C virus research: efficient production of infectious virus in cell culture
    Erica Silberstein
    Laboratory of Hepatitis and Related Emerging Agents, Center for Biologics Evaluation and Research, US Food and Drug Administration
    Int J Biomed Sci 4:82-8. 2008
    ..Here we review the current state-of-the-art and the molecular hurdles that have been met and those that still need to be overcome...