Research Topics
| R ReimschuesselSummaryAffiliation: Food and Drug Administration Country: USA Publications
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Detail Information
Publications
Fish drug analysis--Phish-Pharm: a searchable database of pharmacokinetics data in fishRenate Reimschuessel
Center for Veterinary Medicine, US Food and Drug Administration, 8401 Muirkirk Road, Laurel, MD 20708, USA
AAPS J 7:E288-327. 2005..This database will be a valuable resource to investigators of drug metabolism in aquatic species as well as government and private organizations involved in the drug approval process for aquatic species...
Residue depletion of melamine and cyanuric acid in catfish and rainbow trout following oral administrationR Reimschuessel
Center for Veterinary Medicine, US Food and Drug Administration, Laurel, MD 20708, USA
J Vet Pharmacol Ther 33:172-82. 2010..5 mg/kg by day 3. The half-lives for melamine and cyanuric acid ranged between 1 and 4 days. Renal crystals formed in fish given both melamine and cyanuric acid, persisting for weeks after the single dose...
Renal crystal formation after combined or sequential oral administration of melamine and cyanuric acidR Reimschuessel
Center for Veterinary Medicine, US Food and Drug Administration, 8401 Muirkirk Rd, Laurel, MD 20708, USA
Food Chem Toxicol 48:2898-906. 2010..Since fish generally excrete chemicals more slowly than mammals, they may provide a "worst case scenario" model for higher risk populations, such as infants or persons with compromised renal function...
Metabolism and depletion of albendazole in the muscle tissue of channel catfish following oral treatmentB Shaikh
Food and Drug Administration, CVM Office of Research, Laurel, MD 20708, USA
J Vet Pharmacol Ther 29:525-30. 2006..ABZ-SO2 was present at 1 microg/kg concentration levels until 48 h in muscle alone and 72 h in muscle with skin. ABZ-2-NH2SO2 was not detected at any withdrawal periods...
Metabolism and residue depletion of albendazole and its metabolites in rainbow trout, tilapia and Atlantic salmon after oral administrationB Shaikh
Food and Drug Administration, Center for Veterinary Medicine, Office of Research, Laurel, MD 20708, USA
J Vet Pharmacol Ther 26:421-7. 2003....
Residue depletion of albendazole and its metabolites in aquacultured yellow perch (Perca flavescens)D Yu
US Food and Drug Administration, Center for Veterinary Medicine, Office of Research, Laurel, MD 20708, USA
J Vet Pharmacol Ther 35:560-2. 2012..The results of this study suggest that albendazole sulfone metabolite could potentially serve as MR for albendazole in yellow perch muscle, similar to channel catfish and hybrid striped bass as reported previously by us...
New nephron development in goldfish (Carassius auratus) kidneys following repeated gentamicin-induced nephrotoxicosisC J Salice
US Food and Drug Administration, Center for Veterinary Medicine, Office of Research, Laurel, Maryland 20708, USA
Comp Med 51:56-9. 2001..Such information is a prerequisite for developing alternative renal replacement therapies based on the induction of de novo nephrogenesis in diseased kidneys...
Myxosporean plasmodial infection associated with ulcerative lesions in young-of-the-year Atlantic menhaden in a tributary of the Chesapeake Bay, and possible links to Kudoa clupeidaeR Reimschuessel
US Food and Drug Administration, Center for Veterinary Medicine, Office of Research, Laurel, Maryland 20708, USA
Dis Aquat Organ 53:143-66. 2003..Our ultrastructural studies indicate that the plasmodial organisms, which are important in the etiology of the skin lesions, are myxozoans, and they may represent early stages of K. clupeidae...
