Patrick F McDermott

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. ncbi request reprint Ciprofloxacin resistance in Campylobacter jejuni evolves rapidly in chickens treated with fluoroquinolones
    Patrick F McDermott
    Division of Animal and Food Microbiology, Center for Veterinary Medicine, US Food and Drug Administration, Laurel, Maryland 20708, USA
    J Infect Dis 185:837-40. 2002
  2. ncbi request reprint Antimicrobials: modes of action and mechanisms of resistance
    Patrick F McDermott
    Office of Research, Center for Veterinary Medicine, US Food and Drug Administration, Laurel, Maryland 20708, USA
    Int J Toxicol 22:135-43. 2003
  3. pmc Antimicrobial drug resistance in Escherichia coli from humans and food animals, United States, 1950-2002
    Daniel A Tadesse
    Food and Drug Administration, Laurel, Maryland 20708, USA
    Emerg Infect Dis 18:741-9. 2012
  4. ncbi request reprint Antimicrobial susceptibility and molecular characterization of avian pathogenic Escherichia coli isolates
    Shaohua Zhao
    Office of Research, Center for Veterinary Medicine, U S Food and Drug Administration, 8401 Muirkirk Road, Laurel, MD 20708, USA
    Vet Microbiol 107:215-24. 2005
  5. ncbi request reprint Identification of antimicrobial resistance and class 1 integrons in Shiga toxin-producing Escherichia coli recovered from humans and food animals
    Ruby Singh
    Division of Animal and Food Microbiology, Office of Research, Center for Veterinary Medicine, U S Food and Drug Administration, Laurel, MD 20708, USA
    J Antimicrob Chemother 56:216-9. 2005
  6. ncbi request reprint Heterogeneity of vat(E)-carrying plasmids in Enterococcus faecium recovered from human and animal sources
    Shabbir Simjee
    Division of Animal and Food Microbiology, Office of Research, Center for Veterinary Medicine, U S Food and Drug Administration, Laurel, MD, USA
    Int J Antimicrob Agents 28:200-5. 2006
  7. ncbi request reprint The US national antimicrobial resistance monitoring system
    Jeffrey M Gilbert
    Center for Veterinary Medicine, US FDA, Office of New Animal Drug Evaluation 7500 Standish Place Rockville, MD 20855, USA
    Future Microbiol 2:493-500. 2007
  8. pmc Characterization of integron mediated antimicrobial resistance in Salmonella isolated from diseased swine
    David G White
    Center for Veterinary Medicine, U S Food and Drug Administration, Office of Research, 8401 Muirkirk Road, Laurel, Maryland, USA 20708
    Can J Vet Res 67:39-47. 2003
  9. ncbi request reprint Antimicrobial resistance among gram-negative foodborne bacterial pathogens associated with foods of animal origin
    David G White
    Office of Research, Center for Veterinary Medicine, U S Food and Drug Administration, Laurel, Maryland 20708, USA
    Foodborne Pathog Dis 1:137-52. 2004
  10. pmc Changes in antimicrobial susceptibility of native Enterococcus faecium in chickens fed virginiamycin
    Patrick F McDermott
    Office of Research, Center for Veterinary Medicine, U S Food and Drug Administration, 8401 Muirkirk Road, Laurel, MD 20708, USA
    Appl Environ Microbiol 71:4986-91. 2005

Collaborators

Detail Information

Publications38

  1. ncbi request reprint Ciprofloxacin resistance in Campylobacter jejuni evolves rapidly in chickens treated with fluoroquinolones
    Patrick F McDermott
    Division of Animal and Food Microbiology, Center for Veterinary Medicine, US Food and Drug Administration, Laurel, Maryland 20708, USA
    J Infect Dis 185:837-40. 2002
    ....
  2. ncbi request reprint Antimicrobials: modes of action and mechanisms of resistance
    Patrick F McDermott
    Office of Research, Center for Veterinary Medicine, US Food and Drug Administration, Laurel, Maryland 20708, USA
    Int J Toxicol 22:135-43. 2003
    ..Successful management of current antimicrobials, and the continued development of new ones, is vital to protecting human and animal health against bacterial pathogens...
  3. pmc Antimicrobial drug resistance in Escherichia coli from humans and food animals, United States, 1950-2002
    Daniel A Tadesse
    Food and Drug Administration, Laurel, Maryland 20708, USA
    Emerg Infect Dis 18:741-9. 2012
    ..0%). These data describe the evolution of resistance after introduction of new antimicrobial agents into clinical medicine and help explain the range of resistance in modern E. coli isolates...
  4. ncbi request reprint Antimicrobial susceptibility and molecular characterization of avian pathogenic Escherichia coli isolates
    Shaohua Zhao
    Office of Research, Center for Veterinary Medicine, U S Food and Drug Administration, 8401 Muirkirk Road, Laurel, MD 20708, USA
    Vet Microbiol 107:215-24. 2005
    ..Twenty-two distinct ribogroups were identified, with 61% of isolates clustering into four major ribogroups, indicating that quinolone resistance has emerged among multiple avian pathogenic E. coli serogroups and chromosomal backgrounds...
  5. ncbi request reprint Identification of antimicrobial resistance and class 1 integrons in Shiga toxin-producing Escherichia coli recovered from humans and food animals
    Ruby Singh
    Division of Animal and Food Microbiology, Office of Research, Center for Veterinary Medicine, U S Food and Drug Administration, Laurel, MD 20708, USA
    J Antimicrob Chemother 56:216-9. 2005
    ..The objective of this study was to identify antimicrobial resistance and class 1 integrons among Shiga toxin-producing Escherichia coli (STEC)...
  6. ncbi request reprint Heterogeneity of vat(E)-carrying plasmids in Enterococcus faecium recovered from human and animal sources
    Shabbir Simjee
    Division of Animal and Food Microbiology, Office of Research, Center for Veterinary Medicine, U S Food and Drug Administration, Laurel, MD, USA
    Int J Antimicrob Agents 28:200-5. 2006
    ..This study showed that the vat(E) gene, conferring resistance to Q/D, was carried on different plasmids in a heterogeneous group of E. faecium, some of which may be acquired by E. faecium capable of infecting humans...
  7. ncbi request reprint The US national antimicrobial resistance monitoring system
    Jeffrey M Gilbert
    Center for Veterinary Medicine, US FDA, Office of New Animal Drug Evaluation 7500 Standish Place Rockville, MD 20855, USA
    Future Microbiol 2:493-500. 2007
    ..These activities help insure that antimicrobials are used judiciously to promote human and animal health...
  8. pmc Characterization of integron mediated antimicrobial resistance in Salmonella isolated from diseased swine
    David G White
    Center for Veterinary Medicine, U S Food and Drug Administration, Office of Research, 8401 Muirkirk Road, Laurel, Maryland, USA 20708
    Can J Vet Res 67:39-47. 2003
    ..This research suggests that integrons contribute to antimicrobial resistance among specific swine Salmonella serotypes; however, they are not as widely disseminated among non-Typhimurium swine Salmonella serotypes as previously thought...
  9. ncbi request reprint Antimicrobial resistance among gram-negative foodborne bacterial pathogens associated with foods of animal origin
    David G White
    Office of Research, Center for Veterinary Medicine, U S Food and Drug Administration, Laurel, Maryland 20708, USA
    Foodborne Pathog Dis 1:137-52. 2004
    ..A clearer understanding of the ecology of resistance is needed in order to support science-based assessments of the public health risks due to the use of antimicrobials in the animal husbandry environment...
  10. pmc Changes in antimicrobial susceptibility of native Enterococcus faecium in chickens fed virginiamycin
    Patrick F McDermott
    Office of Research, Center for Veterinary Medicine, U S Food and Drug Administration, 8401 Muirkirk Road, Laurel, MD 20708, USA
    Appl Environ Microbiol 71:4986-91. 2005
    ..faecium in the animals. The bases of resistance could not be explained by known genetic determinants...
  11. ncbi request reprint Antimicrobial susceptibility and distribution of antimicrobial-resistance genes among Enterococcus and coagulase-negative Staphylococcus isolates recovered from poultry litter
    Shabbir Simjee
    Center for Veterinary Medicine, U S Food and Drug Administration, 8401 Muirkirk Road, Laurel, MD 20708, USA
    Avian Dis 51:884-92. 2007
    ....
  12. ncbi request reprint Antimicrobial resistance of foodborne pathogens
    David G White
    Office of Research, Center for Veterinary Medicine, US Food and Drug Administration, Laurel, MD 20708, USA
    Microbes Infect 4:405-12. 2002
    ....
  13. pmc Broth microdilution susceptibility testing of Campylobacter jejuni and the determination of quality control ranges for fourteen antimicrobial agents
    Patrick F McDermott
    Center for Veterinary Medicine, U S Food and Drug Administration, 8401 Muirkirk Road, Laurel, MD 20708, USA
    J Clin Microbiol 43:6136-8. 2005
    ..Cation-adjusted Mueller-Hinton broth containing 2.5% laked horse blood was the preferred medium, with incubation in a microaerobic atmosphere of 10% CO(2), 5% O(2), and 85% N(2) at 36 degrees C for 48 h or 42 degrees C for 24 h...
  14. pmc Genome sequences of five Salmonella enterica serovar Heidelberg isolates associated with a 2011 multistate outbreak in the United States
    Maria Hoffmann
    Division of Animal and Food Microbiology, Office of Research, Center for Veterinary Medicine, U S Food and Drug Administration, Laurel, Maryland, USA
    J Bacteriol 194:3274-5. 2012
    ..Whole-genome sequence analysis of these isolates provides a tool for studying the short-term evolution of these epidemic clones...
  15. doi request reprint Retrospective Analysis of Salmonella, Campylobacter, Escherichia coli, and Enterococcus in Animal Feed Ingredients
    Beilei Ge
    1 Division of Animal and Food Microbiology, Office of Research, Center for Veterinary Medicine, U S Food and Drug Administration, Laurel, Maryland
    Foodborne Pathog Dis 10:684-91. 2013
    ..coli, and Enterococcus are commonly present in animal feed ingredients, but antimicrobial resistance is not common. Future large-scale studies to monitor these pathogenic and indicator organisms in feed commodities is warranted. ..
  16. doi request reprint Antimicrobial resistance in Campylobacter: Susceptibility testing methods and resistance trends
    Beilei Ge
    Division of Animal and Food Microbiology, Office of Research, Center for Veterinary Medicine, U S Food and Drug Administration, Laurel, MD 20708, USA Electronic address
    J Microbiol Methods 95:57-67. 2013
    ..Nonetheless, variations in susceptibility observed over time underscore the need for continued public health monitoring of Campylobacter resistance from humans, animals, and food. ..
  17. ncbi request reprint A DNA microarray for identification of virulence and antimicrobial resistance genes in Salmonella serovars and Escherichia coli
    Sheng Chen
    Department of Nutrition and Food Science, University of Maryland, 0112 Skinner Building, College Park, MD 20742, USA
    Mol Cell Probes 19:195-201. 2005
    ..Microarray analysis is an effective method to rapidly screen Salmonella and E. coli for multiple antimicrobial resistance and virulence genes...
  18. pmc International spread of multidrug-resistant Salmonella Schwarzengrund in food products
    Frank M Aarestrup
    National Food Institute, Technical University of Denmark, Copenhagen, Denmark
    Emerg Infect Dis 13:726-31. 2007
    ..This study suggests spread of multidrug-resistant S. Schwarzengrund from chickens to persons in Thailand, and from imported Thai food products to persons in Denmark and the United States...
  19. pmc Agar dilution and disk diffusion susceptibility testing of Campylobacter spp
    Thomas R Fritsche
    J Clin Microbiol 45:2758-9; author reply 2759. 2007
  20. pmc Standardizing antimicrobial susceptibility testing of Campylobacter species
    Patrick F McDermott
    J Clin Microbiol 41:1810. 2003
  21. pmc The marC gene of Escherichia coli is not involved in multiple antibiotic resistance
    Patrick F McDermott
    Antimicrob Agents Chemother 52:382-3. 2008
  22. pmc Antimicrobial resistance of Escherichia coli O26, O103, O111, O128, and O145 from animals and humans
    Carl M Schroeder
    University of Maryland, College Park, USA
    Emerg Infect Dis 8:1409-14. 2002
    ..Findings from this study suggest antimicrobial resistance is widespread among E. coli O26, O103, O111, O128, and O145 inhabiting humans and food animals...
  23. pmc Characterization of Salmonella enterica serovar Heidelberg from turkey-associated sources
    Pravin Kaldhone
    Marshfield Clinic Research Foundation, 1000 North Oak Avenue, Marshfield, WI 54449, USA
    Appl Environ Microbiol 74:5038-46. 2008
    ..Conjugation experiments indicated that resistance to multiple antimicrobial agents was transferable among strains with diverse PFGE profiles...
  24. pmc Class 1 integron-associated tobramycin-gentamicin resistance in Campylobacter jejuni isolated from the broiler chicken house environment
    Margie D Lee
    Department of Medical Microbiology and Parasitology Athens Diagnostic Laboratory Department of Environmental Health Sciences, The University of Georgia, Athens, Georgia 30602, USA
    Antimicrob Agents Chemother 46:3660-4. 2002
    ..DNA sequencing demonstrated that all five isolates possessed the aminoglycoside resistance gene, aacA4...
  25. ncbi request reprint Comparison of the Etest and agar dilution for in vitro antimicrobial susceptibility testing of Campylobacter
    Beilei Ge
    Department of Nutrition and Food Science, University of Maryland, College Park, MD 20742, USA
    J Antimicrob Chemother 50:487-94. 2002
    ..The study also showed that C. jejuni and C. coli isolates resistant to antimicrobials used for treating campylobacteriosis were common in retail raw meats...
  26. pmc Characterization of chloramphenicol resistance in beta-hemolytic Escherichia coli associated with diarrhea in neonatal swine
    Kenneth M Bischoff
    Southern Plains Agricultural Research Center, Agricultural Research Service, U S Department of Agriculture, College Station, Texas 77845, USA
    J Clin Microbiol 40:389-94. 2002
    ..The identification of the cmlA gene among diverse hemolytic enterotoxigenic E. coli strains demonstrates its broad dissemination in the swine production environment and its persistence even in the absence of CHL selection pressure...
  27. ncbi request reprint Rapid and widespread dissemination of multidrug-resistant blaCMY-2 Salmonella Typhimurium in Mexico
    Mussaret B Zaidi
    Depto de Investigacion, Laboratorio de Investigacion, Hospital General O Horan, Av Itzaes x Jacinto Canek, Mérida C P 97000, Yucatan, Mexico
    J Antimicrob Chemother 60:398-401. 2007
    ..We describe the emergence and dissemination of multidrug-resistant (MDR) Salmonella Typhimurium in humans, retail meat and food animals from Yucatan, Mexico...
  28. pmc Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials
    Sheng Chen
    Department of Nutrition and Food Science, 0112 Skinner Building, University of Maryland, College Park, MD 20742, USA
    Antimicrob Agents Chemother 51:535-42. 2007
    ....
  29. ncbi request reprint Evaluation of molecular typing methods for Escherichia coli O157:H7 isolates from cattle, food, and humans
    Steven L Foley
    Department of Biology, University of Central Arkansas, Conway, Arkansas 72035, USA
    J Food Prot 67:651-7. 2004
    ..Additionally, there did not appear to be any correlation among the typing methods examined in this study. Therefore, to date, PFGE remains the technique of choice for molecular subtyping of E. coli O157:H7...
  30. pmc Role of efflux pumps and topoisomerase mutations in fluoroquinolone resistance in Campylobacter jejuni and Campylobacter coli
    Beilei Ge
    Department of Nutrition and Food Science, 0112 Skinner Building, University of Maryland, College Park, MD 20742, USA
    Antimicrob Agents Chemother 49:3347-54. 2005
    ..These two mechanisms work synergistically in acquiring and maintaining fluoroquinolone resistance in Campylobacter species...
  31. pmc Characterization of multiple-antimicrobial-resistant salmonella serovars isolated from retail meats
    Sheng Chen
    Department of Nutrition and Food Science, University of Maryland, College Park, Maryland 20742, USA
    Appl Environ Microbiol 70:1-7. 2004
    ..These mobile DNA elements have likely played an important role in transmission and dissemination of antimicrobial resistance determinants among Salmonella strains...
  32. ncbi request reprint Nontyphoidal Salmonella from human clinical cases, asymptomatic children, and raw retail meats in Yucatan, Mexico
    Mussaret B Zaidi
    Laboratorio de Investigacion, Hospital General O Horan, Merida, Yucatan, Mexico
    Clin Infect Dis 42:21-8. 2006
    ..We report the results of a 3-year Salmonella surveillance study of persons with diarrhea; asymptomatic children; and retail pork, poultry, and beef in Yucatan, Mexico...
  33. ncbi request reprint Isolation of antimicrobial-resistant Escherichia coli from retail meats purchased in Greater Washington, DC, USA
    Carl M Schroeder
    Department of Nutrition and Food Science, University of Maryland, College Park, MD 20742, USA
    Int J Food Microbiol 85:197-202. 2003
    ..Findings from this study indicate that retail raw meats may often be contaminated with antimicrobial-resistant E. coli...
  34. pmc Effect of conventional and organic production practices on the prevalence and antimicrobial resistance of Campylobacter spp. in poultry
    Taradon Luangtongkum
    Department of Veterinary Preventive Medicine, Ohio State University, 1920 Coffey Road, Columbus, OH 43210, USA
    Appl Environ Microbiol 72:3600-7. 2006
    ..Findings from this study clearly indicate the influence of conventional and organic poultry production practices on antimicrobial resistance of Campylobacter on poultry farms...
  35. ncbi request reprint Fitness of antimicrobial-resistant Campylobacter and Salmonella
    Qijing Zhang
    Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50011, USA
    Microbes Infect 8:1972-8. 2006
    ....
  36. pmc Antimicrobial-resistant Campylobacter species from retail raw meats
    Beilei Ge
    Department of Nutrition and Food Science, University of Maryland, College Park, MD 20742, USA
    Appl Environ Microbiol 69:3005-7. 2003
    ..Campylobacter coli displayed significantly higher rates of resistance to ciprofloxacin and erythromycin than Campylobacter jejuni, and Campylobacter isolates from turkey meat showed a greater resistance than those from chicken meat...
  37. pmc Comparison of subtyping methods for differentiating Salmonella enterica serovar Typhimurium isolates obtained from food animal sources
    Steven L Foley
    National Farm Medicine Center, Marshfield Clinic Research Foundation, Marshfield, WI 54449, USA
    J Clin Microbiol 44:3569-77. 2006
    ..enterica serovar Typhimurium isolates that genetically cluster according to one particular typing method...
  38. pmc Antimicrobial resistance of Escherichia coli O157 isolated from humans, cattle, swine, and food
    Carl M Schroeder
    Department of Nutrition and Food Science, 3304 Marie Mount Hall, University of Maryland, College Park, MD 20742, USA
    Appl Environ Microbiol 68:576-81. 2002
    ....