Vladimir Y Lugovtsev

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. ncbi Changes of the receptor-binding properties of influenza B virus B/Victoria/504/2000 during adaptation in chicken eggs
    Vladimir Y Lugovtsev
    Laboratory of Respiratory Viruses, Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 Rockville Pike, Bldg 29A, Room 2B17, Bethesda, MD 20892, USA
    Virology 394:218-26. 2009
  2. ncbi Generation of the influenza B viruses with improved growth phenotype by substitution of specific amino acids of hemagglutinin
    Vladimir Y Lugovtsev
    Laboratory of Pediatric and Respiratory Viral Diseases, Division of Viral Products, Office of Vaccine Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Virology 365:315-23. 2007
  3. ncbi Mutational pattern of influenza B viruses adapted to high growth replication in embryonated eggs
    Vladimir Y Lugovtsev
    Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, USA
    Virus Res 109:149-57. 2005
  4. ncbi Simple and rapid strategy for genetic characterization of influenza B virus reassortants
    Vladimir Y Lugovtsev
    Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, USA
    J Virol Methods 124:203-10. 2005
  5. ncbi An alternative method for preparation of pandemic influenza strain-specific antibody for vaccine potency determination
    Falko Schmeisser
    Division of Viral Products, Center for Biologics Evaluations and Research, Food and Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, United States
    Vaccine 28:2442-9. 2010

Collaborators

  • Zhiping Ye
  • Falko Schmeisser
  • Jerry P Weir
  • Richard R Stout
  • Galina M Vodeiko

Detail Information

Publications5

  1. ncbi Changes of the receptor-binding properties of influenza B virus B/Victoria/504/2000 during adaptation in chicken eggs
    Vladimir Y Lugovtsev
    Laboratory of Respiratory Viruses, Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 Rockville Pike, Bldg 29A, Room 2B17, Bethesda, MD 20892, USA
    Virology 394:218-26. 2009
    ..In all cases when the effects on virus binding of individual amino acid substitutions differed, the effect of R162M was subordinate to the effect of either G141E or D196Y...
  2. ncbi Generation of the influenza B viruses with improved growth phenotype by substitution of specific amino acids of hemagglutinin
    Vladimir Y Lugovtsev
    Laboratory of Pediatric and Respiratory Viral Diseases, Division of Viral Products, Office of Vaccine Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Virology 365:315-23. 2007
    ..The results of our studies demonstrate that introduction of specific AA substitutions into viral HA can improve viral replicative efficiency while preserving the original antigenic properties...
  3. ncbi Mutational pattern of influenza B viruses adapted to high growth replication in embryonated eggs
    Vladimir Y Lugovtsev
    Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, USA
    Virus Res 109:149-57. 2005
    ..Specific modifications of genes or a combination of genes could be used to optimize or create influenza B viruses for specific growth substrates...
  4. ncbi Simple and rapid strategy for genetic characterization of influenza B virus reassortants
    Vladimir Y Lugovtsev
    Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, USA
    J Virol Methods 124:203-10. 2005
    ..This method should be useful in basic research applications and in preparing reassortant viruses for vaccine use...
  5. ncbi An alternative method for preparation of pandemic influenza strain-specific antibody for vaccine potency determination
    Falko Schmeisser
    Division of Viral Products, Center for Biologics Evaluations and Research, Food and Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, United States
    Vaccine 28:2442-9. 2010
    ....