Shyh Ching Lo

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. pmc Isolation and characterization of two novel bacteria Afipia cberi and Mesorhizobium hominis from blood of a patient afflicted with fatal pulmonary illness
    Shyh Ching Lo
    Tissue Microbiology Laboratory, Division of Cellular and Gene Therapies, Office of Cellular, Tissue and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, United States of America
    PLoS ONE 8:e82673. 2013
  2. pmc Identification and characterization of EBV genomes in spontaneously immortalized human peripheral blood B lymphocytes by NGS technology
    Haiyan Lei
    Tissue Microbiology Laboratory, Division of Cellular and Gene Therapies, Office of Cellular, Tissue and Gene Therapy, Center for Biologics Evaluation and Research, Food and Drug Administration, NIH Building 29B, RM, 1NN06, 29 Lincoln Dr, 20892 4555 Bethesda, MD, USA
    BMC Genomics 14:804. 2013
  3. pmc Detection of MLV-related virus gene sequences in blood of patients with chronic fatigue syndrome and healthy blood donors
    Shyh Ching Lo
    Center for Biologics Evaluation and Research, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 107:15874-9. 2010
  4. pmc Isolation of novel Afipia septicemium and identification of previously unknown bacteria Bradyrhizobium sp. OHSU_III from blood of patients with poorly defined illnesses
    Shyh Ching Lo
    Tissue Microbiology Laboratory, Division of Cellular and Gene Therapies, Office of Cellular, Tissue and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, United States of America
    PLoS ONE 8:e76142. 2013
  5. pmc Development of real-time PCR array for simultaneous detection of eight human blood-borne viral pathogens
    Natalia Pripuzova
    Tissue Microbiology Laboratory, Division of Cellular and Gene Therapies, Office of Cellular, Tissue and Gene Therapy, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, United States of America
    PLoS ONE 7:e43246. 2012
  6. doi request reprint Differentially expressed genes and pathways induced by organophosphates in human neuroblastoma cells
    Tianwei Li
    Tissue Safety Laboratory Program, Center for Biologics Evaluation and Research, Food and Drug Administration, NIH Building 29B, 29 Lincoln Drive, Bethesda, MD 20892, USA
    Exp Biol Med (Maywood) 237:1413-23. 2012
  7. pmc In Vitro and In Vivo studies of monoclonal antibodies with prominent bactericidal activity against Burkholderia pseudomallei and Burkholderia mallei
    Shimin Zhang
    Department of Environmental and Infectious Disease Sciences, American Registry of Pathology, Armed Forces Institute of Pathology, Washington, DC 20306, USA
    Clin Vaccine Immunol 18:825-34. 2011
  8. pmc Identification of DNA signatures suitable for use in development of real-time PCR assays by whole-genome sequence approaches: use of Streptococcus pyogenes in a pilot study
    Guo Chiuan Hung
    Tissue Microbiology Laboratory, Division of Cellular and Gene Therapies, Office of Cellular, Tissue and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA
    J Clin Microbiol 50:2770-3. 2012

Collaborators

  • Jing Zhang
  • Jing Han
  • Guo Chiuan Hung
  • Bingjie Li
  • Shien Tsai
  • Tianwei Li
  • Haiyan Lei
  • Natalia Pripuzova
  • Shimin Zhang
  • Kenjiro Nagamine
  • Richard Wang
  • Roger G Ptak
  • Raj K Puri
  • Hongtao Zhao
  • Joe Rodriguez
  • Shaw Huey Feng
  • Hyung Yong Kim

Detail Information

Publications9

  1. pmc Isolation and characterization of two novel bacteria Afipia cberi and Mesorhizobium hominis from blood of a patient afflicted with fatal pulmonary illness
    Shyh Ching Lo
    Tissue Microbiology Laboratory, Division of Cellular and Gene Therapies, Office of Cellular, Tissue and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, United States of America
    PLoS ONE 8:e82673. 2013
    ..Specific probes and methods will be developed to re-examine the diseased lungs from patient's autopsy. ..
  2. pmc Identification and characterization of EBV genomes in spontaneously immortalized human peripheral blood B lymphocytes by NGS technology
    Haiyan Lei
    Tissue Microbiology Laboratory, Division of Cellular and Gene Therapies, Office of Cellular, Tissue and Gene Therapy, Center for Biologics Evaluation and Research, Food and Drug Administration, NIH Building 29B, RM, 1NN06, 29 Lincoln Dr, 20892 4555 Bethesda, MD, USA
    BMC Genomics 14:804. 2013
    ..The purpose of this study was to examine if rapid detection and characterization of a viral agent could be effectively achieved by HTS using a platform that has become readily available in general biology laboratories...
  3. pmc Detection of MLV-related virus gene sequences in blood of patients with chronic fatigue syndrome and healthy blood donors
    Shyh Ching Lo
    Center for Biologics Evaluation and Research, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 107:15874-9. 2010
    ....
  4. pmc Isolation of novel Afipia septicemium and identification of previously unknown bacteria Bradyrhizobium sp. OHSU_III from blood of patients with poorly defined illnesses
    Shyh Ching Lo
    Tissue Microbiology Laboratory, Division of Cellular and Gene Therapies, Office of Cellular, Tissue and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, United States of America
    PLoS ONE 8:e76142. 2013
    ..Our studies show that improvement of culture system plus effective use of NGS technology can facilitate findings of infections by unusual microbes in patients having poorly-defined, sometimes mysterious illnesses. ..
  5. pmc Development of real-time PCR array for simultaneous detection of eight human blood-borne viral pathogens
    Natalia Pripuzova
    Tissue Microbiology Laboratory, Division of Cellular and Gene Therapies, Office of Cellular, Tissue and Gene Therapy, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, United States of America
    PLoS ONE 7:e43246. 2012
    ..Real-time PCR array for rapid detection of multiple viral pathogens should be highly useful in cases where the sample volume and the time of testing are limited, i.e. in the eligibility testing of tissue and organ donors...
  6. doi request reprint Differentially expressed genes and pathways induced by organophosphates in human neuroblastoma cells
    Tianwei Li
    Tissue Safety Laboratory Program, Center for Biologics Evaluation and Research, Food and Drug Administration, NIH Building 29B, 29 Lincoln Drive, Bethesda, MD 20892, USA
    Exp Biol Med (Maywood) 237:1413-23. 2012
    ..In addition, these results could also contribute to the development of new prevention and/or therapeutic regimens against OP toxicity...
  7. pmc In Vitro and In Vivo studies of monoclonal antibodies with prominent bactericidal activity against Burkholderia pseudomallei and Burkholderia mallei
    Shimin Zhang
    Department of Environmental and Infectious Disease Sciences, American Registry of Pathology, Armed Forces Institute of Pathology, Washington, DC 20306, USA
    Clin Vaccine Immunol 18:825-34. 2011
    ..The result is compatible with that of our in vitro study. The MAbs with the highest protective efficacy are those reactive to either the capsular PS or LPS of the Burkholderia bacteria...
  8. pmc Identification of DNA signatures suitable for use in development of real-time PCR assays by whole-genome sequence approaches: use of Streptococcus pyogenes in a pilot study
    Guo Chiuan Hung
    Tissue Microbiology Laboratory, Division of Cellular and Gene Therapies, Office of Cellular, Tissue and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA
    J Clin Microbiol 50:2770-3. 2012
    ..The approach is readily applicable for designing molecular assays for rapid detection and characterization of various pathogenic bacteria...