Juhong Liu

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. ncbi JTV1 co-activates FBP to induce USP29 transcription and stabilize p53 in response to oxidative stress
    Juhong Liu
    Gene Regulation Section, Laboratory of Pathology, National Cancer Institute, Bethesda, MD, USA
    EMBO J 30:846-58. 2011
  2. ncbi FBPs are calibrated molecular tools to adjust gene expression
    Hye-Jung Chung
    Laboratory of Pathology, CCR, NCI, Bldg. 10, Rm. 2N106, Bethesda, MD 20892-1500, USA
    Mol Cell Biol 26:6584-97. 2006
  3. ncbi The FUSE/FBP/FIR/TFIIH system is a molecular machine programming a pulse of c-myc expression
    Juhong Liu
    Laboratory of Pathology, National Cancer Institute, Bethesda, MD 20892 1500, USA
    EMBO J 25:2119-30. 2006
  4. ncbi Hierarchical mechanisms build the DNA-binding specificity of FUSE binding protein
    Lawrence R Benjamin
    Gene Regulation Section, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Building 10, Room 2N106, Bethesda, MD 20892 1500, USA
    Proc Natl Acad Sci U S A 105:18296-301. 2008
  5. ncbi TFIIH operates through an expanded proximal promoter to fine-tune c-myc expression
    Achim Weber
    Gene Regulation Section, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute NIH, Bldg 10, Rm 2N106, Bethesda, MD 20892 1500, USA
    Mol Cell Biol 25:147-61. 2005
  6. ncbi XPB induces C1D expression to counteract UV-induced apoptosis
    Guang Li
    Pediatric Tumor Biology and Ultrastructural Pathology Section, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892 1500, USA
    Mol Cancer Res 8:885-95. 2010
  7. ncbi The dynamic response of upstream DNA to transcription-generated torsional stress
    Fedor Kouzine
    Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland 20892 1500, USA
    Nat Struct Mol Biol 11:1092-100. 2004

Collaborators

Detail Information

Publications7

  1. ncbi JTV1 co-activates FBP to induce USP29 transcription and stabilize p53 in response to oxidative stress
    Juhong Liu
    Gene Regulation Section, Laboratory of Pathology, National Cancer Institute, Bethesda, MD, USA
    EMBO J 30:846-58. 2011
    ..The accumulated p53 quickly induces apoptosis. Thus, FBP and JTV1 help to coordinate the molecular and cellular response to oxidative stress...
  2. ncbi FBPs are calibrated molecular tools to adjust gene expression
    Hye-Jung Chung
    Laboratory of Pathology, CCR, NCI, Bldg. 10, Rm. 2N106, Bethesda, MD 20892-1500, USA
    Mol Cell Biol 26:6584-97. 2006
    ....
  3. ncbi The FUSE/FBP/FIR/TFIIH system is a molecular machine programming a pulse of c-myc expression
    Juhong Liu
    Laboratory of Pathology, National Cancer Institute, Bethesda, MD 20892 1500, USA
    EMBO J 25:2119-30. 2006
    ..Engineering FUSE into episomal vectors predictably re-programmed metallothionein-promoter-driven reporter expression. The in vitro recruitment of FBP and FIR to dynamically stressed c-myc DNA paralleled the in vivo process...
  4. ncbi Hierarchical mechanisms build the DNA-binding specificity of FUSE binding protein
    Lawrence R Benjamin
    Gene Regulation Section, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Building 10, Room 2N106, Bethesda, MD 20892 1500, USA
    Proc Natl Acad Sci U S A 105:18296-301. 2008
    ....
  5. ncbi TFIIH operates through an expanded proximal promoter to fine-tune c-myc expression
    Achim Weber
    Gene Regulation Section, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute NIH, Bldg 10, Rm 2N106, Bethesda, MD 20892 1500, USA
    Mol Cell Biol 25:147-61. 2005
    ..This helps to suppress the intrinsic noise of transcription and to ensure the steady transcriptional output of c-myc necessary for cellular homeostasis...
  6. ncbi XPB induces C1D expression to counteract UV-induced apoptosis
    Guang Li
    Pediatric Tumor Biology and Ultrastructural Pathology Section, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892 1500, USA
    Mol Cancer Res 8:885-95. 2010
    ..Our findings provided direct evidence that C1D is associated with DNA repair complex and may promote repair of UV-induced DNA damage...
  7. ncbi The dynamic response of upstream DNA to transcription-generated torsional stress
    Fedor Kouzine
    Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland 20892 1500, USA
    Nat Struct Mol Biol 11:1092-100. 2004
    ..An alternative non-B conformation of FUSE found in stably supercoiled DNA is not accessible dynamically. These results demonstrate that dynamic disturbance of DNA structure provides a real-time measure of ongoing genetic activity...