Che Hung Lee
Affiliation: Food and Drug Administration
- Preparation and characterization of an immunogenic meningococcal group A conjugate vaccine for use in AfricaChe Hung Lee
Center for Biologics Evaluation and Research, Bethesda, MD 20892, USA
Vaccine 27:726-32. 2009..Lancet 2003, 361:1092-4]. A phase 1 clinical trial of the manufactured Men A-TT conjugate vaccine has been successfully carried out in adults in India, and a phase 2 clinical trial in young children is currently underway in Africa...
- Comparison of Neisseria meningitidis serogroup W135 polysaccharide-tetanus toxoid conjugate vaccines made by periodate activation of O-acetylated, non-O-acetylated and chemically de-O-acetylated polysaccharideSeshu K Gudlavalleti
Laboratory of Bacterial Polysaccharides, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
Vaccine 25:7972-80. 2007..Thus, for W135, PS O-acetylation does not contribute a dominant immunogenic epitope. The OAc(-) PS may be a good starting material for preparing W135 PS-TT conjugate vaccines using periodate oxidation...