Research Topics
| Arifa S KhanSummaryAffiliation: Food and Drug Administration Country: USA Publications
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Detail Information
Publications
Simian foamy virus infection by whole-blood transfer in rhesus macaques: potential for transfusion transmission in humansArifa S Khan
Laboratory of Retrovirus Research, Division of Viral Products, Center for Biologics Evaluation and Research, U S Food and Drug Administration, Bethesda, Maryland, USA
Transfusion 46:1352-9. 2006..The persistence of infectious virus in peripheral blood mononuclear cells (PBMNC) and the recent identification of some infected blood donors has raised safety concerns regarding potential virus transmission by blood transfusion...
Proposed algorithm to investigate latent and occult viruses in vaccine cell substrates by chemical inductionArifa S Khan
Laboratory of Retrovirus Research, Center for Biologics, Evaluation and Research, US Food and Drug Administration, Bethesda, MD 20892, USA
Biologicals 37:196-201. 2009....
Simian foamy virus infection in humans: prevalence and managementArifa S Khan
Laboratory of Retrovirus Research, Division of Viral Products, Center for Biologics Evaluation and Research, US Food and Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, USA
Expert Rev Anti Infect Ther 7:569-80. 2009..These steps will help prevent the emergence of a novel pathogen and reduce the risk of transmission of another potential pathogenic human retrovirus...
Investigation of xenotropic murine leukemia virus-related virus (XMRV) in human and other cell linesDhanya K Williams
Laboratory of Retroviruses, Division of Viral Products, Center for Biologics Evaluation and Research, U S Food and Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, USA
Biologicals 39:378-83. 2011..The results indicated the absence of XMRV in the cell lines tested; although in some cases DNA fragments identified as cellular sequences were seen following the first round of PCR amplification with the env primer pair...
Chemical induction of endogenous retrovirus particles from the vero cell line of African green monkeysHailun Ma
Laboratory of Retroviruses, Division of Viral Products, Center for Biologics Evaluation and Research, U S Food and Drug Administration, 8800 Rockville Pike, HFM 454, Bldg 29B, Room 4NN10, Bethesda, MD 20892, USA
J Virol 85:6579-88. 2011..The results indicated that multiple, inducible endogenous retrovirus loci are present in the AGM genome that can encode noninfectious, viruslike particles...
Role of neutralizing antibodies in controlling simian foamy virus transmission and infectionDhanya K Williams
Laboratory of Retroviruses, Division of Viral Products, Center for Biologics Evaluation and Research, U S Food and Drug Administration, Bethesda, Maryland, USA
Transfusion 50:200-7. 2010..These results suggested a role for NAbs in SFV transmission and establishment of infection...
Optimization of chemical induction conditions for human herpesvirus 8 (HHV-8) reactivation with 12-O-tetradecanoyl-phorbol-13-acetate (TPA) from latently-infected BC-3 cellsWenbin Ma
Laboratory of Retroviruses, Division of Viral Products, Center for Biologics Evaluation and Research, U S Food and Drug Administration, Bethesda, MD 20892, USA
Biologicals 39:158-66. 2011..The results demonstrate the use of a step-wise strategy with chemical induction that may facilitate broad detection of latent DNA viruses and novel virus discovery...
Investigations of porcine circovirus type 1 (PCV1) in vaccine-related and other cell linesHailun Ma
Center for Biologics Evaluation and Research, US Food and Drug Administration, Bethesda, MD 20892, USA
Vaccine 29:8429-37. 2011....
Detection of Latent Retroviruses in Vaccine-related Cell Substrates: Investigation of RT Activity Produced by Chemical Induction of Vero CellsHailun Ma
Laboratory of Retroviruses, Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, U S Food and Drug Administration
PDA J Pharm Sci Technol 65:685-9. 2011..This approach may be used for enhancing vaccine safety by assessing the presence of potential chemically-inducible, latent viruses in cell substrates to be used for vaccine manufacture...
