J Kanungo

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. doi request reprint Ketamine induces motor neuron toxicity and alters neurogenic and proneural gene expression in zebrafish
    Jyotshna Kanungo
    Division of Neurotoxicology, National Center for Toxicological Research, US Food and Drug Administration, 3900 NCTR Road, Jefferson, AR 72079, USA
    J Appl Toxicol 33:410-7. 2013
  2. doi request reprint Nicotine alters the expression of molecular markers of endocrine disruption in zebrafish
    Jyotshna Kanungo
    Division of Neurotoxicology, National Center for Toxicological Research, US Food and Drug Administration, 3900 NCTR Road, Jefferson, AR 72079, USA
    Neurosci Lett 526:133-7. 2012
  3. doi request reprint L-Carnitine rescues ketamine-induced attenuated heart rate and MAPK (ERK) activity in zebrafish embryos
    Jyotshnabala Kanungo
    Division of Neurotoxicology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA
    Reprod Toxicol 33:205-12. 2012
  4. doi request reprint In vivo imaging and quantitative analysis of changes in axon length using transgenic zebrafish embryos
    Jyotshnabala Kanungo
    Division of Neurotoxicology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA
    Neurotoxicol Teratol 33:618-23. 2011
  5. pmc Menin induces endodermal differentiation in aggregated P19 stem cells by modulating the retinoic acid receptors
    Jyotshnabala Kanungo
    Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, 50 South Dr, Bldg 50, Room 5232, Bethesda, MD 20892, USA
    Mol Cell Biochem 359:95-104. 2012
  6. doi request reprint Disruption of blastomeric F-actin: a potential early biomarker of developmental toxicity in zebrafish
    Jyotshnabala Kanungo
    Division of Neurotoxicology, National Center for Toxicological Research, U S Food and Drug Administration, 3900 NCTR Road, Jefferson, AR 72079, USA
    Mol Cell Biochem 353:283-90. 2011
  7. ncbi request reprint Gradual loss of DNA-PK activity from the cytoplasm is coincident with the nuclear translocation of its activator Ku during early development of Xenopus laevis
    J Kanungo
    Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, Georgia, USA
    Folia Biol (Praha) 55:218-23. 2009
  8. doi request reprint Exogenously expressed human Ku70 stabilizes Ku80 in Xenopus oocytes and induces heterologous DNA-PK catalytic activity
    Jyotshnabala Kanungo
    Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA 30912, USA
    Mol Cell Biochem 338:291-8. 2010
  9. ncbi request reprint Microinjection of an antibody to the Ku protein arrests development in sea urchin embryos
    J Kanungo
    Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta 30912, USA
    Biol Bull 197:341-7. 1999

Detail Information

Publications10

  1. doi request reprint Ketamine induces motor neuron toxicity and alters neurogenic and proneural gene expression in zebrafish
    Jyotshna Kanungo
    Division of Neurotoxicology, National Center for Toxicological Research, US Food and Drug Administration, 3900 NCTR Road, Jefferson, AR 72079, USA
    J Appl Toxicol 33:410-7. 2013
    ..Published 2011. This article is a US Government work and is in the public domain in the USA...
  2. doi request reprint Nicotine alters the expression of molecular markers of endocrine disruption in zebrafish
    Jyotshna Kanungo
    Division of Neurotoxicology, National Center for Toxicological Research, US Food and Drug Administration, 3900 NCTR Road, Jefferson, AR 72079, USA
    Neurosci Lett 526:133-7. 2012
    ..These results provide direct molecular evidence that nicotine is an endocrine disruptor in zebrafish...
  3. doi request reprint L-Carnitine rescues ketamine-induced attenuated heart rate and MAPK (ERK) activity in zebrafish embryos
    Jyotshnabala Kanungo
    Division of Neurotoxicology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA
    Reprod Toxicol 33:205-12. 2012
    ..These findings demonstrate that l-carnitine counteracts ketamine's negative effects on heart rate and ERK activity in zebrafish embryos...
  4. doi request reprint In vivo imaging and quantitative analysis of changes in axon length using transgenic zebrafish embryos
    Jyotshnabala Kanungo
    Division of Neurotoxicology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR 72079, USA
    Neurotoxicol Teratol 33:618-23. 2011
    ..5°C. These test experiments demonstrate that using axon development as an end-point, compound screening can be performed in a time-efficient manner...
  5. pmc Menin induces endodermal differentiation in aggregated P19 stem cells by modulating the retinoic acid receptors
    Jyotshnabala Kanungo
    Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, 50 South Dr, Bldg 50, Room 5232, Bethesda, MD 20892, USA
    Mol Cell Biochem 359:95-104. 2012
    ..Moreover, endodermal differentiation was inhibited by the pan-RAR antagonist Ro41-5253, suggesting that menin could induce endodermal differentiation of uncommitted cells by functionally modulating the RARs...
  6. doi request reprint Disruption of blastomeric F-actin: a potential early biomarker of developmental toxicity in zebrafish
    Jyotshnabala Kanungo
    Division of Neurotoxicology, National Center for Toxicological Research, U S Food and Drug Administration, 3900 NCTR Road, Jefferson, AR 72079, USA
    Mol Cell Biochem 353:283-90. 2011
    ..In this review, we discuss the potential use of F-actin disruption as a predictive biomarker of developmental toxicity in zebrafish...
  7. ncbi request reprint Gradual loss of DNA-PK activity from the cytoplasm is coincident with the nuclear translocation of its activator Ku during early development of Xenopus laevis
    J Kanungo
    Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, Georgia, USA
    Folia Biol (Praha) 55:218-23. 2009
    ....
  8. doi request reprint Exogenously expressed human Ku70 stabilizes Ku80 in Xenopus oocytes and induces heterologous DNA-PK catalytic activity
    Jyotshnabala Kanungo
    Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA 30912, USA
    Mol Cell Biochem 338:291-8. 2010
    ....
  9. ncbi request reprint Microinjection of an antibody to the Ku protein arrests development in sea urchin embryos
    J Kanungo
    Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta 30912, USA
    Biol Bull 197:341-7. 1999
    ..In either case, the results suggest that DNA-PK plays an important role in regulating the early stages of embryogenesis in this primitive organism...