Satoshi Inoue

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. ncbi request reprint Programming of CTL with heat-killed Brucella abortus and antigen allows soluble antigen alone to generate effective secondary CTL
    Satoshi Inoue
    Center for Biologics Evaluation and Research, Division of Hematology, Food and Drug Administration, Bethesda, MD 20892, USA
    Vaccine 23:1730-8. 2005
  2. ncbi request reprint Inhibitory effects of B cells on antitumor immunity
    Satoshi Inoue
    Center for Biologics Evaluation and Research, Division of Hematology, Food and Drug Administration, 1401 Rockville Pike, Rockville, MD 20852, USA
    Cancer Res 66:7741-7. 2006
  3. ncbi request reprint Systemic and mucosal immunity in rhesus macaques immunized with HIV-1 peptide and gp120 conjugated to Brucella abortus
    Nancy Eller
    Laboratory of Plasma Derivatives, Division of Hematology, Office of Blood Research and Review, Bethesda, MD 20892, USA
    J Med Primatol 33:167-74. 2004
  4. ncbi request reprint Augmentation of immune cell activity against tumor cells by Rauwolfia radix
    Guang Bi Jin
    Department of Geriatric Medicine, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    J Ethnopharmacol 81:365-72. 2002
  5. ncbi request reprint Inhibition of Src kinase activity by Ad-mda7 suppresses vascular endothelial growth factor expression in prostate carcinoma cells
    Satoshi Inoue
    Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, 77030, USA
    Mol Ther 12:707-15. 2005
  6. ncbi request reprint Expression of estrogen-responsive finger protein (Efp) is associated with advanced disease in human epithelial ovarian cancer
    Michiko Sakuma
    Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, 1 1 Seiryo machi, Aoba ku, Sendai 980 8574, Japan
    Gynecol Oncol 99:664-70. 2005
  7. ncbi request reprint A retrovirus restriction factor TRIM5alpha is transcriptionally regulated by interferons
    Kentaro Asaoka
    Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical School, Saitama, Japan
    Biochem Biophys Res Commun 338:1950-6. 2005
  8. ncbi request reprint Identification of novel steroid target genes through the combination of bioinformatics and functional analysis of hormone response elements
    Kuniko Horie-Inoue
    Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical School, 1397 1 Yamane, Hidaka shi, Saitama 350 1241, Japan
    Biochem Biophys Res Commun 339:99-106. 2006
  9. pmc Antitumor activity and downregulation of pro-angiogenic molecules in human prostate cancer cells by a novel thiazolidione compound
    Fuminori Teraishi
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Prostate 66:430-8. 2006
  10. ncbi request reprint Diethylstilbestrol increases the density of prolactin cells in male mouse pituitary by inducing proliferation of prolactin cells and transdifferentiation of gonadotropic cells
    Keiko Shukuwa
    Division of Histology and Cell Biology, Department of Developmental and Reconstructive Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1 12 4 Sakamoto, 852 8523, Nagasaki, Japan
    Histochem Cell Biol 126:111-23. 2006

Collaborators

  • W W Leitner
  • H Golding
  • Rajagopal Ramesh
  • Keisuke Yanagida
  • Tadaichi Kitamura
  • Kazuo Nakamichi
  • H Tanaka
  • Min Lin
  • Michiko Sakuma
  • Kuniko Horie-Inoue
  • Yasuyoshi Ouchi
  • Tomohiko Urano
  • Masami Muramatsu
  • Jinpei Kumagai
  • Tetsuya Fujimura
  • Kenichi Takayama
  • Kazuhiro Ikeda
  • Satoru Takahashi
  • Shigehiro Miyachi
  • Yoshitaka Hishikawa
  • Takehiko Koji
  • Tetsuo Ogushi
  • Shigeki Kato
  • Alessandro Natoni
  • Fuminori Teraishi
  • Norie Nakasato
  • Keiko Shukuwa
  • Masahiko Takada
  • Chun Ho Park
  • Satoru Takeda
  • Akio Yamada
  • Yasuhisa Oida
  • Kentaro Asaoka
  • Kuniaki Ejima
  • Kotaro Azuma
  • Bruce Blumberg
  • Yurie Motoi
  • Yasushi Okazaki
  • Kinjiro Morimoto
  • Hironobu Sasano
  • Takashi Suzuki
  • Jun ichi Akahira
  • Nancy Eller
  • Youko Shoji
  • Naoe Tamaru
  • Michelle M Tabb
  • Toshifumi Tsurusaki
  • Takahiro Tsuburai
  • Guang Bi Jin
  • Kayoko Murakami
  • Yoshihide Hayashizaki
  • Kenta Kobayashi
  • Gerald M Cohen
  • Hideki Hanawa
  • Yasunobu Yasoshima
  • Kazuto Kobayashi
  • Ken ichi Inoue
  • Aneela Majid
  • Takashi Shimada
  • Renata Walewska
  • David R Stover
  • Marion MacFarlane
  • Deborah Knee
  • Martin J S Dyer
  • Mariko Kondo
  • John J Davis
  • Toshifumi Oyamada
  • Hidemasa U Bono
  • Hiroyasu Yoshikawa
  • Takashi Kitaoka
  • Shin Ichi Izumi
  • Shuhong Wu
  • Lidong Zhang
  • Bingliang Fang
  • Akira Noguchi
  • Wei Guo
  • Fengqin Dong
  • Xiaofeng Lu
  • Toshiki Hishinuma
  • Ryuichi Sakai
  • Sunil Chada
  • Takamasa Uekita
  • Jack A Roth
  • Atsushi Nambu
  • Abner M Mhashilkar
  • B Nebiyou Bekele
  • Masamitsu Tanaka
  • Takuya Iwasaki
  • E Lin
  • Hajime Hatta

Detail Information

Publications34

  1. ncbi request reprint Programming of CTL with heat-killed Brucella abortus and antigen allows soluble antigen alone to generate effective secondary CTL
    Satoshi Inoue
    Center for Biologics Evaluation and Research, Division of Hematology, Food and Drug Administration, Bethesda, MD 20892, USA
    Vaccine 23:1730-8. 2005
    ....
  2. ncbi request reprint Inhibitory effects of B cells on antitumor immunity
    Satoshi Inoue
    Center for Biologics Evaluation and Research, Division of Hematology, Food and Drug Administration, 1401 Rockville Pike, Rockville, MD 20852, USA
    Cancer Res 66:7741-7. 2006
    ..Our studies provide the first mechanistic basis for the concept that B-cell depletion could therapeutically enhance antitumor immune responses to certain tumors by decreasing IL-10 production from B cells...
  3. ncbi request reprint Systemic and mucosal immunity in rhesus macaques immunized with HIV-1 peptide and gp120 conjugated to Brucella abortus
    Nancy Eller
    Laboratory of Plasma Derivatives, Division of Hematology, Office of Blood Research and Review, Bethesda, MD 20892, USA
    J Med Primatol 33:167-74. 2004
    ....
  4. ncbi request reprint Augmentation of immune cell activity against tumor cells by Rauwolfia radix
    Guang Bi Jin
    Department of Geriatric Medicine, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    J Ethnopharmacol 81:365-72. 2002
    ..Taken together, our results suggest that Rauwolfia radix can enhance the activity of immune cells against tumor cells...
  5. ncbi request reprint Inhibition of Src kinase activity by Ad-mda7 suppresses vascular endothelial growth factor expression in prostate carcinoma cells
    Satoshi Inoue
    Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, 77030, USA
    Mol Ther 12:707-15. 2005
    ..Our findings demonstrate that MDA-7 protein, in addition to inhibiting tumor angiogenesis directly, inhibits angiogenesis indirectly by inhibiting VEGF production by tumor cells...
  6. ncbi request reprint Expression of estrogen-responsive finger protein (Efp) is associated with advanced disease in human epithelial ovarian cancer
    Michiko Sakuma
    Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, 1 1 Seiryo machi, Aoba ku, Sendai 980 8574, Japan
    Gynecol Oncol 99:664-70. 2005
    ..To understand the estrogenic action on ovarian cancer, we studied the relationships between Efp and ERs expressions and the correlations of Efp expression with clinicopathological parameters in epithelial ovarian cancer...
  7. ncbi request reprint A retrovirus restriction factor TRIM5alpha is transcriptionally regulated by interferons
    Kentaro Asaoka
    Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical School, Saitama, Japan
    Biochem Biophys Res Commun 338:1950-6. 2005
    ..These results lead us to define that the transcription and protein synthesis of TRIM5alpha could be modulated by IFN, suggesting that TRIM5alpha may play a role in an IFN-induced antiviral state against retrovirus infection...
  8. ncbi request reprint Identification of novel steroid target genes through the combination of bioinformatics and functional analysis of hormone response elements
    Kuniko Horie-Inoue
    Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical School, 1397 1 Yamane, Hidaka shi, Saitama 350 1241, Japan
    Biochem Biophys Res Commun 339:99-106. 2006
    ..The present data suggest that the combination of bioinformatics analysis and quantitative experimental evaluation is useful to identify novel functional HREs that may contribute to the transcriptional regulation of steroid target genes...
  9. pmc Antitumor activity and downregulation of pro-angiogenic molecules in human prostate cancer cells by a novel thiazolidione compound
    Fuminori Teraishi
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Prostate 66:430-8. 2006
    ..Here, we investigated the antitumor properties and mechanisms of action of this compound in human prostate cancer cell lines...
  10. ncbi request reprint Diethylstilbestrol increases the density of prolactin cells in male mouse pituitary by inducing proliferation of prolactin cells and transdifferentiation of gonadotropic cells
    Keiko Shukuwa
    Division of Histology and Cell Biology, Department of Developmental and Reconstructive Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1 12 4 Sakamoto, 852 8523, Nagasaki, Japan
    Histochem Cell Biol 126:111-23. 2006
    ..Our results indicate that DES increases PRL cells by inducing proliferation of PRL cells and transdifferentiation of FSH/LH cells to PRL cells...
  11. ncbi request reprint The histopathogenesis of paralytic rabies in six-week-old C57BL/6J mice following inoculation of the CVS-11 strain into the right triceps surae muscle
    Chun Ho Park
    Department of Veterinary Pathology, School of Veterinary Medicine and Animal Sciences, Kitasato University, Towada, Japan
    J Vet Med Sci 68:589-95. 2006
    ..The virus primarily replicated in the muscles was ascended the spinal cord via afferent fibers and retrogradely invaded the cerebrum, and with subsequent spread to muscle spindles...
  12. ncbi request reprint A ubiquitin E3 ligase Efp is up-regulated by interferons and conjugated with ISG15
    Norie Nakasato
    Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, Saitama, Japan
    Biochem Biophys Res Commun 351:540-6. 2006
    ..These data suggest that Efp is an IFN-responsive gene that potentially mediates IFN actions, involved in ISGylation and ubiquitination of proteins including Efp itself...
  13. ncbi request reprint mda-7 In combination with bevacizumab treatment produces a synergistic and complete inhibitory effect on lung tumor xenograft
    Satoshi Inoue
    Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Mol Ther 15:287-94. 2007
    ..Thus, Ad-mda7 and bevacizumab treatment produces a synergistic and complete therapeutic effect against human lung cancer...
  14. ncbi request reprint Increased expression of estrogen-related receptor alpha (ERRalpha) is a negative prognostic predictor in human prostate cancer
    Tetsuya Fujimura
    Department of Urology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan
    Int J Cancer 120:2325-30. 2007
    ..0141 and 0.0367, respectively). The enhanced expression of ERRalpha might play a role in the development of human PC and serve as a significant prognostic factor for the disease...
  15. ncbi request reprint Cytochrome P450 2B6 is a growth-inhibitory and prognostic factor for prostate cancer
    Jinpei Kumagai
    Department of Urology, The University of Tokyo, Hongo, Bunkyo ku, Tokyo, Japan
    Prostate 67:1029-37. 2007
    ..Among them, Cytochrome P450 2B6 (CYP2B6) plays a critical role in the deactivation of testosterone. In the present study, we examined CYP2B6 expression in human prostate tissues and prostate cancer...
  16. ncbi request reprint TRAIL signals to apoptosis in chronic lymphocytic leukaemia cells primarily through TRAIL-R1 whereas cross-linked agonistic TRAIL-R2 antibodies facilitate signalling via TRAIL-R2
    Alessandro Natoni
    MRC Toxicology Unit, University of Leicester, Leicester, UK
    Br J Haematol 139:568-77. 2007
    ..Such information is clearly important for the rational optimisation of TRAIL therapy in primary lymphoid malignancies, such as CLL...
  17. ncbi request reprint Efficient gene transfer via retrograde transport in rodent and primate brains using a human immunodeficiency virus type 1-based vector pseudotyped with rabies virus glycoprotein
    Shigeki Kato
    Department of Molecular Genetics, Institute of Biomedical Sciences, Fukushima Medical University School of Medicine, Fukushima 9601295, Japan
    Hum Gene Ther 18:1141-51. 2007
    ..This primate lentiviral vector system will provide a powerful approach to gene therapy for neurological and neurodegenerative diseases by means of enhanced retrograde transport...
  18. ncbi request reprint Tyrosine phosphorylation of paxillin affects the metastatic potential of human osteosarcoma
    Kotaro Azuma
    Growth Factor Division, National Cancer Center Research Institute, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Oncogene 24:4754-64. 2005
    ..These findings suggest that enhanced activity of Src family kinases and overexpression of paxillin synergistically contribute to the high metastatic potential of human osteosarcoma through the hyperphosphorylation of paxillin...
  19. ncbi request reprint Production of rabies neutralizing antibody in hen's eggs using a part of the G protein expressed in Escherichia coli
    Yurie Motoi
    The United Graduate School of Veterinary Science, Gifu University, 501 1193 Yanagido 1 1, Gifu, Japan
    Vaccine 23:3026-32. 2005
    ..coli could serve as a possible alternative to currently available anti-rabies human or equine immunoglobulins...
  20. ncbi request reprint Adenovirus-mediated transfer and overexpression of heme oxygenase 1 cDNA in lung prevents bleomycin-induced pulmonary fibrosis via a Fas-Fas ligand-independent pathway
    Takahiro Tsuburai
    First Department of Internal Medicine, Yokohama City University School of Medicine, Yokohama, Kanagawa, Japan
    Hum Gene Ther 13:1945-60. 2002
    ....
  21. ncbi request reprint Zone-dependent expression of estrogen receptors alpha and beta in human benign prostatic hyperplasia
    Toshifumi Tsurusaki
    Department of Urology, The Japanese Red Cross Nagasaki Atomic Bomb Hospital, Nagasaki 852 8511, Japan
    J Clin Endocrinol Metab 88:1333-40. 2003
    ..ERbeta-positive epithelial cells were evenly distributed in PZ and TZ of the prostate. Our results suggest that estrogen may play a crucial role in the pathogenesis of benign prostatic hyperplasia through ERbeta...
  22. ncbi request reprint Cross-reactive antigenicity of nucleoproteins of lyssaviruses recognized by a monospecific antirabies virus nucleoprotein antiserum on paraffin sections of formalin-fixed tissues
    Satoshi Inoue
    Department of Veterinary Science, National Institute of Infectious Diseases, Tokyo, Japan
    Pathol Int 53:525-33. 2003
    ....
  23. ncbi request reprint Vitamin K2 regulation of bone homeostasis is mediated by the steroid and xenobiotic receptor SXR
    Michelle M Tabb
    Department of Developmental and Cell Biology, University of California, Irvine, California 92697 2300, USA
    J Biol Chem 278:43919-27. 2003
    ..An important implication of this work is that a subset of SXR activators may function as effective therapeutic agents for the management of osteoporosis...
  24. ncbi request reprint Safe and easy monitoring of anti-rabies antibody in dogs using his-tagged recombinant N-protein
    Satoshi Inoue
    Department of Veterinary Science, National Institute of Infectious Diseases, Tokyo 162 8640, Japan
    Jpn J Infect Dis 56:158-60. 2003
    ..A safe and convenient test using His-rNP would contribute to our understanding of the status of herd immunity among not only domestic dogs but also stray dogs in Japan...
  25. ncbi request reprint Assembly of the silk fibroin elementary unit in endoplasmic reticulum and a role of L-chain for protection of alpha1,2-mannose residues in N-linked oligosaccharide chains of fibrohexamerin/P25
    Satoshi Inoue
    Department of Molecular and Cell Biology, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan
    Eur J Biochem 271:356-66. 2004
    ..Models suggesting a role of L-chain for the protection of alpha1,2-mannose residues of fhx/P25 are presented...
  26. ncbi request reprint Generation and characterization of P gene-deficient rabies virus
    Youko Shoji
    Department of Veterinary Science, National Institute of Infectious Diseases, Shinjuku, Tokyo 162 8640, Japan
    Virology 318:295-305. 2004
    ..These results demonstrate the potential utility of gene-deficient virus as a novel live attenuated rabies vaccine...
  27. ncbi request reprint Preparation of a positive control DNA for molecular diagnosis of Bacillus anthracis
    Satoshi Inoue
    Department of Veterinary Science, National Institute of Infectious Diseases, Tokyo 162 8640, Japan
    Jpn J Infect Dis 57:29-32. 2004
    ..It also allows the detection of possible cross contamination, indicating that this strategy would be useful and convenient for the molecular identification of not only B. anthracis but also other highly pathogenic microbes...
  28. ncbi request reprint Decreased expression of 14-3-3 sigma is associated with advanced disease in human epithelial ovarian cancer: its correlation with aberrant DNA methylation
    Jun ichi Akahira
    Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan
    Clin Cancer Res 10:2687-93. 2004
    ..In this study, we examined the promoter methylation status and expression of 14-3-3 sigma and evaluated its clinical significance in epithelial ovarian cancer...
  29. ncbi request reprint 14-3-3sigma is down-regulated in human prostate cancer
    Tomohiko Urano
    Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Biochem Biophys Res Commun 319:795-800. 2004
    ..These data suggest that 14-3-3sigma expression is down-regulated during the neoplastic transition of prostate epithelial cells...
  30. ncbi request reprint Estrogen receptor-associated expression of keratinocyte growth factor and its possible role in the inhibition of apoptosis in human breast cancer
    Naoe Tamaru
    Division of Histology and Cell Biology, Department of Developmental and Reconstructive Medicine, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan
    Lab Invest 84:1460-71. 2004
    ..Collectively, our results indicate that ER alpha may be involved in KGF expression, and that KGF may play antiapoptotic roles, rather than mitogenic, in human breast cancer...
  31. ncbi request reprint Identification and functional analysis of consensus androgen response elements in human prostate cancer cells
    Kuniko Horie-Inoue
    Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical School, 1397 1 Yamane, Hidaka shi, Saitama 350 1241, Japan
    Biochem Biophys Res Commun 325:1312-7. 2004
    ..Our results suggest that some of perfect palindromic AREs could function as in vivo AR binding sites in the human genome and regulate gene transcription...
  32. ncbi request reprint Sulindac enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human lung cancer
    Yasuhisa Oida
    Department of Thoracic and Cardiovascular Surgery, University of Texas M D Anderson Cancer Center, Unit 445, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Mol Cancer Ther 4:291-304. 2005
    ..Regulation of protein turnover is a heretofore-unrecognized mechanism of this nonsteroidal anti-inflammatory drug...
  33. ncbi request reprint Organization of multisynaptic inputs from prefrontal cortex to primary motor cortex as revealed by retrograde transneuronal transport of rabies virus
    Shigehiro Miyachi
    Department of System Neuroscience, Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research, Fuchu, Tokyo 183 8526, Japan
    J Neurosci 25:2547-56. 2005
    ..The present results suggest the importance of ventral area 46 in the cognitive control of forelimb movements...
  34. doi request reprint FOXP1 is an androgen-responsive transcription factor that negatively regulates androgen receptor signaling in prostate cancer cells
    Kenichi Takayama
    Department of Geriatric Medicine, Graduate School of Medicine, University of Tokyo, Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Biochem Biophys Res Commun 374:388-93. 2008
    ..Our study provides a new insight to the function of forkhead transcription factors that modulates AR signaling as an androgen-regulated transcriptional factor, which would contribute to the tumorigenesis of prostate cancer...