Monique P Gelderman

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. doi request reprint Current and future cellular transfusion products
    Monique P Gelderman
    Laboratory of Cellular Hematology, Division of Hematology, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike, Rockville, MD 20852 1448, USA
    Clin Lab Med 30:443-52. 2010
  2. doi request reprint Rejuvenation improves roller pump-induced physical stress resistance of fresh and stored red blood cells
    Monique P Gelderman
    Laboratory of Cellular Hematology, Division of Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, Maryland 20852 1448, USA
    Transfusion 51:1096-104. 2011
  3. doi request reprint Activation of platelet protein kinase C by ultraviolet light B mediates platelet transfusion-related acute lung injury in a two-event animal model
    Li Zhi
    Laboratory of Cellular Hematology, Division of Hematology, OBRR, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA
    Transfusion 53:722-31. 2013
  4. pmc Host platelets and, in part, neutrophils mediate lung accumulation of transfused UVB-irradiated human platelets in a mouse model of acute lung injury
    Xuan Chi
    Laboratory of Cellular Hematology, Division of Hematology, OBRR, Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, Maryland, United States of America
    PLoS ONE 7:e44829. 2012
  5. doi request reprint Temperature cycling improves in vivo recovery of cold-stored human platelets in a mouse model of transfusion
    Fei Xu
    Laboratory of Cellular Hematology, Center for Biologics Evaluation and Research, FDA, Bethesda, Maryland 20852 1448, USA
    Transfusion 53:1178-86. 2013
  6. doi request reprint Carbon nanotubes activate blood platelets by inducing extracellular Ca2+ influx sensitive to calcium entry inhibitors
    Jana Semberova
    Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, Maryland 20852 1448, USA
    Nano Lett 9:3312-7. 2009
  7. ncbi request reprint Cell membrane microparticles in blood and blood products: potentially pathogenic agents and diagnostic markers
    Jan Simak
    Laboratory of Cellular Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD, USA
    Transfus Med Rev 20:1-26. 2006
  8. doi request reprint Flow cytometric analysis of cell membrane microparticles
    Monique P Gelderman
    Laboratory of Cellular Hematology, CBER FDA, Rockville, MD, USA
    Methods Mol Biol 484:79-93. 2008
  9. doi request reprint Ultraviolet B light-exposed human platelets mediate acute lung injury in a two-event mouse model of transfusion
    Monique P Gelderman
    Laboratory of Cellular Hematology, Division of Hematology, OBRR, Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, Maryland 20892, USA
    Transfusion 51:2343-57. 2011
  10. ncbi request reprint In vivo recovery of human platelets in severe combined immunodeficient mice as a measure of platelet damage
    John T Piper
    Laboratory of Cellular Hematology, Division of Hematology, Office of Blood Research and Review, Center for Biologics Evaluation and Research, United States Food and Drug Administration, 1401 Rockville Pike, Rockville, MD 20852, USA
    Transfusion 47:1540-9. 2007

Collaborators

Detail Information

Publications12

  1. doi request reprint Current and future cellular transfusion products
    Monique P Gelderman
    Laboratory of Cellular Hematology, Division of Hematology, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike, Rockville, MD 20852 1448, USA
    Clin Lab Med 30:443-52. 2010
    ..This article reviews the literature and discusses the current and future state of cellular transfusion products...
  2. doi request reprint Rejuvenation improves roller pump-induced physical stress resistance of fresh and stored red blood cells
    Monique P Gelderman
    Laboratory of Cellular Hematology, Division of Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, Maryland 20852 1448, USA
    Transfusion 51:1096-104. 2011
    ..Similar studies were also done on cardiac surgery patients who were placed on cardiac bypass pumps. It is possible that stored RBCs are more fragile and could be more easily damaged by these pumps, thus leading to additional morbidity...
  3. doi request reprint Activation of platelet protein kinase C by ultraviolet light B mediates platelet transfusion-related acute lung injury in a two-event animal model
    Li Zhi
    Laboratory of Cellular Hematology, Division of Hematology, OBRR, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA
    Transfusion 53:722-31. 2013
    ..We have now identified changes in HPs induced by UVB light and responses of the recipient animal that mediate the mTRALI...
  4. pmc Host platelets and, in part, neutrophils mediate lung accumulation of transfused UVB-irradiated human platelets in a mouse model of acute lung injury
    Xuan Chi
    Laboratory of Cellular Hematology, Division of Hematology, OBRR, Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, Maryland, United States of America
    PLoS ONE 7:e44829. 2012
    ..Neutrophils also recruited a small percentage of platelets to the lung. These findings may help develop therapeutic strategies for ALI which could potentially result from transfusion of UV illuminated platelets...
  5. doi request reprint Temperature cycling improves in vivo recovery of cold-stored human platelets in a mouse model of transfusion
    Fei Xu
    Laboratory of Cellular Hematology, Center for Biologics Evaluation and Research, FDA, Bethesda, Maryland 20852 1448, USA
    Transfusion 53:1178-86. 2013
    ..We cycled storage temperature between 4 and 37°C to preserve PLT function and reduce bacterial growth...
  6. doi request reprint Carbon nanotubes activate blood platelets by inducing extracellular Ca2+ influx sensitive to calcium entry inhibitors
    Jana Semberova
    Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, Maryland 20852 1448, USA
    Nano Lett 9:3312-7. 2009
    ..In addition, we show that CNT-induced platelet activation is associated with a marked release of platelet membrane microparticles positive for the granular secretion markers CD62P and CD63...
  7. ncbi request reprint Cell membrane microparticles in blood and blood products: potentially pathogenic agents and diagnostic markers
    Jan Simak
    Laboratory of Cellular Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD, USA
    Transfus Med Rev 20:1-26. 2006
    ..Thus, the investigation of potentially pathogenic effects of MPs in blood products and of MP release associated with blood product processing and storage have yet to come...
  8. doi request reprint Flow cytometric analysis of cell membrane microparticles
    Monique P Gelderman
    Laboratory of Cellular Hematology, CBER FDA, Rockville, MD, USA
    Methods Mol Biol 484:79-93. 2008
    ..A modified version of this assay can also be used for MP analysis in blood products and cell cultures...
  9. doi request reprint Ultraviolet B light-exposed human platelets mediate acute lung injury in a two-event mouse model of transfusion
    Monique P Gelderman
    Laboratory of Cellular Hematology, Division of Hematology, OBRR, Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, Maryland 20892, USA
    Transfusion 51:2343-57. 2011
    ..Clinical trials of UV-treated PLTs in patients with thrombocytopenia generated controversy regarding association of these cells with respiratory distress. We evaluated whether UVB PLTs could mediate ALI in an animal model of ALI...
  10. ncbi request reprint In vivo recovery of human platelets in severe combined immunodeficient mice as a measure of platelet damage
    John T Piper
    Laboratory of Cellular Hematology, Division of Hematology, Office of Blood Research and Review, Center for Biologics Evaluation and Research, United States Food and Drug Administration, 1401 Rockville Pike, Rockville, MD 20852, USA
    Transfusion 47:1540-9. 2007
    ..The severe combined immunodeficient (SCID) mice allowed prolonged circulation of human PLTs and were used to detect differences in recovery and survival between chemically damaged, aged PLTs, or normal PLTs...
  11. doi request reprint Blood aging, safety, and transfusion: capturing the "radical" menace
    Paul W Buehler
    Division of Hematology, Center for Biologics Evaluation and Research, U S Food and Drug Administration, Bethesda, Maryland 20892, USA
    Antioxid Redox Signal 14:1713-28. 2011
    ..Furthermore, some of the same naturally occurring protective mechanisms can potentially be employed to oxidatively inactivate this redox active protein and control its damaging side reactions when released outside of the RBC...
  12. pmc Adverse effects of fullerenes on endothelial cells: fullerenol C60(OH)24 induced tissue factor and ICAM-I membrane expression and apoptosis in vitro
    Monique P Gelderman
    CBER, FDA, 1401 Rockville Pike, HFM 335, Rockville, MD 20852 1448, USA
    Int J Nanomedicine 3:59-68. 2008
    ..In conclusion, fullerenol C60(OH)24 had both pro-inflammatory and pro-apoptotic effects on HUVECs, indicating possible adverse effects of fullerenes on the endothelium...