Jeffrey W Fisher

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. ncbi request reprint Evaluation of iodide deficiency in the lactating rat and pup using a biologically based dose-response model
    Jeffrey W Fisher
    U S Food and Drug Administration, National Center for Toxicological Research, Jefferson, AR, USA
    Toxicol Sci 132:75-86. 2013
  2. doi request reprint Extrapolation of hypothalamic-pituitary-thyroid axis perturbations and associated toxicity in rodents to humans: case study with perchlorate
    Jeffrey Fisher
    Division of Biochemical Toxicology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079, USA
    J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 30:81-105. 2012
  3. doi request reprint Pharmacokinetic modeling: prediction and evaluation of route dependent dosimetry of bisphenol A in monkeys with extrapolation to humans
    Jeffrey W Fisher
    Food and Drug Administration, National Center for Toxicological Research, Division of Biochemical Toxicology, 3900 NCTR Road, Jefferson, AR 72079, USA
    Toxicol Appl Pharmacol 257:122-36. 2011
  4. doi request reprint Pharmacokinetics of bisphenol A in neonatal and adult CD-1 mice: inter-species comparisons with Sprague-Dawley rats and rhesus monkeys
    Daniel R Doerge
    Division of Biochemical Toxicology, National Center for Toxicological Research, U S Food and Drug Administration, Jefferson, AR 72079, USA
    Toxicol Lett 207:298-305. 2011
  5. doi request reprint Pharmacokinetics of bisphenol A in neonatal and adult Sprague-Dawley rats
    Daniel R Doerge
    Division of Biochemical Toxicology, National Center for Toxicological Research, U S Food and Drug Administration, Jefferson, AR 72079, USA
    Toxicol Appl Pharmacol 247:158-65. 2010
  6. doi request reprint Distribution of bisphenol A into tissues of adult, neonatal, and fetal Sprague-Dawley rats
    Daniel R Doerge
    Division of Biochemical Toxicology, National Center for Toxicological Research, U S Food and Drug Administration, Jefferson, AR 72079, USA
    Toxicol Appl Pharmacol 255:261-70. 2011
  7. doi request reprint Concurrent determination of bisphenol A pharmacokinetics in maternal and fetal rhesus monkeys
    Tucker A Patterson
    Division of Neurotoxicology, National Center for Toxicological Research, Jefferson, AR 72079, USA
    Toxicol Appl Pharmacol 267:41-8. 2013
  8. doi request reprint Pharmacokinetics of bisphenol A in neonatal and adult rhesus monkeys
    Daniel R Doerge
    Division of Biochemical Toxicology, National Center for Toxicological Research, U S Food and Drug Administration, Jefferson, AR 72079, USA
    Toxicol Appl Pharmacol 248:1-11. 2010
  9. doi request reprint Pharmacokinetics of bisphenol A in serum and adipose tissue following intravenous administration to adult female CD-1 mice
    Daniel R Doerge
    Division of Biochemical Toxicology, National Center for Toxicological Research, U S Food and Drug Administration, Jefferson, AR 72079, USA
    Toxicol Lett 211:114-9. 2012
  10. doi request reprint Prediction and evaluation of route dependent dosimetry of BPA in rats at different life stages using a physiologically based pharmacokinetic model
    XiaoXia Yang
    Division of Biochemical Toxicology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079, USA
    Toxicol Appl Pharmacol 270:45-59. 2013

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Evaluation of iodide deficiency in the lactating rat and pup using a biologically based dose-response model
    Jeffrey W Fisher
    U S Food and Drug Administration, National Center for Toxicological Research, Jefferson, AR, USA
    Toxicol Sci 132:75-86. 2013
    ..2013)...
  2. doi request reprint Extrapolation of hypothalamic-pituitary-thyroid axis perturbations and associated toxicity in rodents to humans: case study with perchlorate
    Jeffrey Fisher
    Division of Biochemical Toxicology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079, USA
    J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 30:81-105. 2012
    ....
  3. doi request reprint Pharmacokinetic modeling: prediction and evaluation of route dependent dosimetry of bisphenol A in monkeys with extrapolation to humans
    Jeffrey W Fisher
    Food and Drug Administration, National Center for Toxicological Research, Division of Biochemical Toxicology, 3900 NCTR Road, Jefferson, AR 72079, USA
    Toxicol Appl Pharmacol 257:122-36. 2011
    ..The use of the current non-human primate BPA model parameters provides more confidence in predicting the aglycone BPA in serum levels in humans after oral ingestion of BPA...
  4. doi request reprint Pharmacokinetics of bisphenol A in neonatal and adult CD-1 mice: inter-species comparisons with Sprague-Dawley rats and rhesus monkeys
    Daniel R Doerge
    Division of Biochemical Toxicology, National Center for Toxicological Research, U S Food and Drug Administration, Jefferson, AR 72079, USA
    Toxicol Lett 207:298-305. 2011
    ..On the other hand in all adults of all species studied, including humans, a low oral dose of BPA produced similarly small internal exposures for the unconjugated form, reflecting the dominant effect of presystemic Phase II metabolism...
  5. doi request reprint Pharmacokinetics of bisphenol A in neonatal and adult Sprague-Dawley rats
    Daniel R Doerge
    Division of Biochemical Toxicology, National Center for Toxicological Research, U S Food and Drug Administration, Jefferson, AR 72079, USA
    Toxicol Appl Pharmacol 247:158-65. 2010
    ..These findings emphasize the importance of matching aglycone BPA internal dosimetry with receptor affinities in experimental animal studies reporting toxicity...
  6. doi request reprint Distribution of bisphenol A into tissues of adult, neonatal, and fetal Sprague-Dawley rats
    Daniel R Doerge
    Division of Biochemical Toxicology, National Center for Toxicological Research, U S Food and Drug Administration, Jefferson, AR 72079, USA
    Toxicol Appl Pharmacol 255:261-70. 2011
    ....
  7. doi request reprint Concurrent determination of bisphenol A pharmacokinetics in maternal and fetal rhesus monkeys
    Tucker A Patterson
    Division of Neurotoxicology, National Center for Toxicological Research, Jefferson, AR 72079, USA
    Toxicol Appl Pharmacol 267:41-8. 2013
    ..This study in a non-human primate model provides additional pharmacokinetic data for use in PBPK modeling of perinatal exposures to BPA from food contact, medical devices, and other environmental sources...
  8. doi request reprint Pharmacokinetics of bisphenol A in neonatal and adult rhesus monkeys
    Daniel R Doerge
    Division of Biochemical Toxicology, National Center for Toxicological Research, U S Food and Drug Administration, Jefferson, AR 72079, USA
    Toxicol Appl Pharmacol 248:1-11. 2010
    ....
  9. doi request reprint Pharmacokinetics of bisphenol A in serum and adipose tissue following intravenous administration to adult female CD-1 mice
    Daniel R Doerge
    Division of Biochemical Toxicology, National Center for Toxicological Research, U S Food and Drug Administration, Jefferson, AR 72079, USA
    Toxicol Lett 211:114-9. 2012
    ..These plasma and tissue kinetics are consistent with rapid equilibria and underscore the non-persistent nature of BPA, particularly when compared with slowly metabolized lipophilic organic pollutants like halogenated dibenzodioxins...
  10. doi request reprint Prediction and evaluation of route dependent dosimetry of BPA in rats at different life stages using a physiologically based pharmacokinetic model
    XiaoXia Yang
    Division of Biochemical Toxicology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079, USA
    Toxicol Appl Pharmacol 270:45-59. 2013
    ..A comparison of the dosimetry of BPA across immature rats and monkeys suggests that dose adjustments would be necessary to extrapolate toxicity studies from neonatal rats to infant humans...
  11. ncbi request reprint Comparison of life-stage-dependent internal dosimetry for bisphenol A, ethinyl estradiol, a reference estrogen, and endogenous estradiol to test an estrogenic mode of action in Sprague Dawley rats
    Mona I Churchwell
    U S Food and Drug Administration, National Center for Toxicological Research, Division of Biochemical Toxicology, 3900 NCTR Road, Jefferson, Arkansas 72079
    Toxicol Sci 139:4-20. 2014
    ..Such evaluations of estrogenic internal dosimetry and comprehensive evaluation of contamination impact should aid in extrapolating risks from human BPA exposures. ..