Research Topics
| Jeffrey W FisherSummaryAffiliation: Food and Drug Administration Country: USA Publications
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Detail Information
Publications
Evaluation of iodide deficiency in the lactating rat and pup using a biologically based dose-response modelJeffrey W Fisher
U S Food and Drug Administration, National Center for Toxicological Research, Jefferson, AR, USA
Toxicol Sci 132:75-86. 2013..2013)...
Extrapolation of hypothalamic-pituitary-thyroid axis perturbations and associated toxicity in rodents to humans: case study with perchlorateJeffrey Fisher
Division of Biochemical Toxicology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079, USA
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 30:81-105. 2012....
Pharmacokinetic modeling: prediction and evaluation of route dependent dosimetry of bisphenol A in monkeys with extrapolation to humansJeffrey W Fisher
Food and Drug Administration, National Center for Toxicological Research, Division of Biochemical Toxicology, 3900 NCTR Road, Jefferson, AR 72079, USA
Toxicol Appl Pharmacol 257:122-36. 2011..The use of the current non-human primate BPA model parameters provides more confidence in predicting the aglycone BPA in serum levels in humans after oral ingestion of BPA...
Pharmacokinetics of bisphenol A in neonatal and adult CD-1 mice: inter-species comparisons with Sprague-Dawley rats and rhesus monkeysDaniel R Doerge
Division of Biochemical Toxicology, National Center for Toxicological Research, U S Food and Drug Administration, Jefferson, AR 72079, USA
Toxicol Lett 207:298-305. 2011..On the other hand in all adults of all species studied, including humans, a low oral dose of BPA produced similarly small internal exposures for the unconjugated form, reflecting the dominant effect of presystemic Phase II metabolism...
Pharmacokinetics of bisphenol A in neonatal and adult Sprague-Dawley ratsDaniel R Doerge
Division of Biochemical Toxicology, National Center for Toxicological Research, U S Food and Drug Administration, Jefferson, AR 72079, USA
Toxicol Appl Pharmacol 247:158-65. 2010..These findings emphasize the importance of matching aglycone BPA internal dosimetry with receptor affinities in experimental animal studies reporting toxicity...
Distribution of bisphenol A into tissues of adult, neonatal, and fetal Sprague-Dawley ratsDaniel R Doerge
Division of Biochemical Toxicology, National Center for Toxicological Research, U S Food and Drug Administration, Jefferson, AR 72079, USA
Toxicol Appl Pharmacol 255:261-70. 2011....
Concurrent determination of bisphenol A pharmacokinetics in maternal and fetal rhesus monkeysTucker A Patterson
Division of Neurotoxicology, National Center for Toxicological Research, Jefferson, AR 72079, USA
Toxicol Appl Pharmacol 267:41-8. 2013..This study in a non-human primate model provides additional pharmacokinetic data for use in PBPK modeling of perinatal exposures to BPA from food contact, medical devices, and other environmental sources...
Pharmacokinetics of bisphenol A in neonatal and adult rhesus monkeysDaniel R Doerge
Division of Biochemical Toxicology, National Center for Toxicological Research, U S Food and Drug Administration, Jefferson, AR 72079, USA
Toxicol Appl Pharmacol 248:1-11. 2010....
Pharmacokinetics of bisphenol A in serum and adipose tissue following intravenous administration to adult female CD-1 miceDaniel R Doerge
Division of Biochemical Toxicology, National Center for Toxicological Research, U S Food and Drug Administration, Jefferson, AR 72079, USA
Toxicol Lett 211:114-9. 2012..These plasma and tissue kinetics are consistent with rapid equilibria and underscore the non-persistent nature of BPA, particularly when compared with slowly metabolized lipophilic organic pollutants like halogenated dibenzodioxins...
