Robert W Dickey

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. ncbi request reprint Ciguatera: a public health perspective
    Robert W Dickey
    U S FDA Center for Food Safety and Applied Nutrition, Office of Food Safety, Division of Seafood Science and Technology, Gulf Coast Seafood Laboratory, 1 Iberville Drive, Dauphin Island, AL 36528, USA
    Toxicon 56:123-36. 2010
  2. doi request reprint Monitoring of brevetoxins in the Karenia brevis bloom-exposed Eastern oyster (Crassostrea virginica)
    Steven M Plakas
    Gulf Coast Seafood Laboratory, U S Food and Drug Administration, 1 Iberville Drive, Dauphin Island, AL 36528, USA
    Toxicon 52:32-8. 2008
  3. ncbi request reprint Characterization of polar brevetoxin derivatives isolated from Karenia brevis cultures and natural blooms
    Ann Abraham
    Gulf Coast Seafood Laboratory, US Food and Drug Administration, P O Box 158, 1 Iberville Drive, Dauphin Island, AL 36528 0158, USA
    Toxicon 48:104-15. 2006
  4. ncbi request reprint Biomarkers of neurotoxic shellfish poisoning
    Ann Abraham
    Gulf Coast Seafood Laboratory, U S Food and Drug Administration, P O Box 158, 1 Iberville Drive, Dauphin Island, AL 36528 0158, USA
    Toxicon 52:237-45. 2008
  5. ncbi request reprint Brevetoxin metabolism and elimination in the Eastern oyster (Crassostrea virginica) after controlled exposures to Karenia brevis
    Steven M Plakas
    Gulf Coast Seafood Laboratory, US Food and Drug Administration, P O Box 158, 1 Iberville Drive, Dauphin Island, AL 36528 0158, USA
    Toxicon 44:677-85. 2004
  6. ncbi request reprint Advances in monitoring and toxicity assessment of brevetoxins in molluscan shellfish
    Steven M Plakas
    Gulf Coast Seafood Laboratory, U S Food and Drug Administration, 1 Iberville Drive, Dauphin Island, AL 36528, USA
    Toxicon 56:137-49. 2010
  7. ncbi request reprint LC/MS analysis of brevetoxin metabolites in the Eastern oyster (Crassostrea virginica)
    Zhihong Wang
    Gulf Coast Seafood Laboratory, U S Food and Drug Administration, P O Box 158, 1 Iberville Drive, Dauphin Island, AL 36528 0158, USA
    Toxicon 43:455-65. 2004
  8. ncbi request reprint Confirmation of brevetoxin metabolism in the Eastern oyster (Crassostrea virginica) by controlled exposures to pure toxins and to Karenia brevis cultures
    Steven M Plakas
    Gulf Coast Seafood Laboratory, US Food and Drug Administration, 1 Iberville Drive, P O Box 158, Dauphin Island, AL 36528 0158, USA
    Toxicon 40:721-9. 2002

Detail Information

Publications8

  1. ncbi request reprint Ciguatera: a public health perspective
    Robert W Dickey
    U S FDA Center for Food Safety and Applied Nutrition, Office of Food Safety, Division of Seafood Science and Technology, Gulf Coast Seafood Laboratory, 1 Iberville Drive, Dauphin Island, AL 36528, USA
    Toxicon 56:123-36. 2010
    ..10ppb C-CTX-1 equivalent toxicity in fish from the tropical Atlantic, Gulf of Mexico, Caribbean, and 0.01ppb P-CTX-1 equivalent toxicity in fish from Pacific regions...
  2. doi request reprint Monitoring of brevetoxins in the Karenia brevis bloom-exposed Eastern oyster (Crassostrea virginica)
    Steven M Plakas
    Gulf Coast Seafood Laboratory, U S Food and Drug Administration, 1 Iberville Drive, Dauphin Island, AL 36528, USA
    Toxicon 52:32-8. 2008
    ..ELISA and LC-MS methods offer rapid screening and confirmation, respectively, of brevetoxin contamination in the oyster, and are excellent alternatives to mouse bioassay for assessing oyster toxicity following K. brevis blooms...
  3. ncbi request reprint Characterization of polar brevetoxin derivatives isolated from Karenia brevis cultures and natural blooms
    Ann Abraham
    Gulf Coast Seafood Laboratory, US Food and Drug Administration, P O Box 158, 1 Iberville Drive, Dauphin Island, AL 36528 0158, USA
    Toxicon 48:104-15. 2006
    ..In the K. brevis bloom-exposed Eastern oyster, brevetoxin metabolites with opened A rings were identified (e.g., open-ring cysteine-PbTx conjugates), contributing to their overall toxin burden...
  4. ncbi request reprint Biomarkers of neurotoxic shellfish poisoning
    Ann Abraham
    Gulf Coast Seafood Laboratory, U S Food and Drug Administration, P O Box 158, 1 Iberville Drive, Dauphin Island, AL 36528 0158, USA
    Toxicon 52:237-45. 2008
    ..BTX-3 concentrations in urine, as determined by LC-MS/MS, correlated well with composite toxin measurements by ELISA (r(2)=0.96). BTX-3 is a useful biomarker for confirmation of clinical diagnosis of NSP...
  5. ncbi request reprint Brevetoxin metabolism and elimination in the Eastern oyster (Crassostrea virginica) after controlled exposures to Karenia brevis
    Steven M Plakas
    Gulf Coast Seafood Laboratory, US Food and Drug Administration, P O Box 158, 1 Iberville Drive, Dauphin Island, AL 36528 0158, USA
    Toxicon 44:677-85. 2004
    ..Cysteine-PbTx conjugates are useful LC/MS determinants of brevetoxin exposure and potential markers for composite toxin in the Eastern oyster...
  6. ncbi request reprint Advances in monitoring and toxicity assessment of brevetoxins in molluscan shellfish
    Steven M Plakas
    Gulf Coast Seafood Laboratory, U S Food and Drug Administration, 1 Iberville Drive, Dauphin Island, AL 36528, USA
    Toxicon 56:137-49. 2010
    ..Specific and measurable biomarkers of brevetoxin exposure and toxicity in shellfish, and of human intoxication, are described. Their utility in regulatory monitoring of toxic shellfish and in clinical diagnosis of NSP is evaluated...
  7. ncbi request reprint LC/MS analysis of brevetoxin metabolites in the Eastern oyster (Crassostrea virginica)
    Zhihong Wang
    Gulf Coast Seafood Laboratory, U S Food and Drug Administration, P O Box 158, 1 Iberville Drive, Dauphin Island, AL 36528 0158, USA
    Toxicon 43:455-65. 2004
    ..Other brevetoxin derivatives found in oysters are consistent with hydrolytic ring-opening and oxidation/reduction reactions...
  8. ncbi request reprint Confirmation of brevetoxin metabolism in the Eastern oyster (Crassostrea virginica) by controlled exposures to pure toxins and to Karenia brevis cultures
    Steven M Plakas
    Gulf Coast Seafood Laboratory, US Food and Drug Administration, 1 Iberville Drive, P O Box 158, Dauphin Island, AL 36528 0158, USA
    Toxicon 40:721-9. 2002
    ..brevis. PbTx metabolites contribute to neurotoxic shellfish poisoning (NSP) and should be included in analytical protocols for monitoring shellfish toxicity after a K. brevis red tide event...