Qing Chen

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. pmc Different requirements for σ Region 4 in BvgA activation of the Bordetella pertussis promoters P(fim3) and P(fhaB)
    Kimberly B Decker
    Gene Expression and Regulation Section, Laboratory of Molecular and Cellular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    J Mol Biol 409:692-709. 2011
  2. pmc Novel architectural features of Bordetella pertussis fimbrial subunit promoters and their activation by the global virulence regulator BvgA
    Qing Chen
    Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, FDA, Bethesda, MD 20892, USA
    Mol Microbiol 77:1326-40. 2010
  3. pmc In vivo phosphorylation dynamics of the Bordetella pertussis virulence-controlling response regulator BvgA
    Alice Boulanger
    Gene Expression and Regulation Section, Laboratory of Cell and Molecular Biology, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA
    Mol Microbiol 88:156-72. 2013

Collaborators

Detail Information

Publications3

  1. pmc Different requirements for σ Region 4 in BvgA activation of the Bordetella pertussis promoters P(fim3) and P(fhaB)
    Kimberly B Decker
    Gene Expression and Regulation Section, Laboratory of Molecular and Cellular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    J Mol Biol 409:692-709. 2011
    ..Molecular modeling suggests how BvgA, σ Region 4, and α might coexist within this DNA in a conformation that suggests a novel mechanism of activation...
  2. pmc Novel architectural features of Bordetella pertussis fimbrial subunit promoters and their activation by the global virulence regulator BvgA
    Qing Chen
    Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, FDA, Bethesda, MD 20892, USA
    Mol Microbiol 77:1326-40. 2010
    ..However, the lack of a recognizable -35 element (CCCCCC versus TTGACA), and the occupation of this site by BvgA∼P suggest that activation of the fim promoters involves unusual interactions among BvgA, RNA polymerase and promoter DNA...
  3. pmc In vivo phosphorylation dynamics of the Bordetella pertussis virulence-controlling response regulator BvgA
    Alice Boulanger
    Gene Expression and Regulation Section, Laboratory of Cell and Molecular Biology, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA
    Mol Microbiol 88:156-72. 2013
    ..We also detected the phosphorylation of a small but consistent fraction of BvgA purified after expression in Escherichia coli...