Affiliation: Food and Drug Administration
- Different requirements for σ Region 4 in BvgA activation of the Bordetella pertussis promoters P(fim3) and P(fhaB)Kimberly B Decker
Gene Expression and Regulation Section, Laboratory of Molecular and Cellular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
J Mol Biol 409:692-709. 2011..Molecular modeling suggests how BvgA, σ Region 4, and α might coexist within this DNA in a conformation that suggests a novel mechanism of activation...
- Novel architectural features of Bordetella pertussis fimbrial subunit promoters and their activation by the global virulence regulator BvgAQing Chen
Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, FDA, Bethesda, MD 20892, USA
Mol Microbiol 77:1326-40. 2010..However, the lack of a recognizable -35 element (CCCCCC versus TTGACA), and the occupation of this site by BvgA∼P suggest that activation of the fim promoters involves unusual interactions among BvgA, RNA polymerase and promoter DNA...
- In vivo phosphorylation dynamics of the Bordetella pertussis virulence-controlling response regulator BvgAAlice Boulanger
Gene Expression and Regulation Section, Laboratory of Cell and Molecular Biology, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA
Mol Microbiol 88:156-72. 2013..We also detected the phosphorylation of a small but consistent fraction of BvgA purified after expression in Escherichia coli...