R M Blair
Affiliation: Food and Drug Administration
- The estrogen receptor relative binding affinities of 188 natural and xenochemicals: structural diversity of ligandsR M Blair
Division of Genetic and Reproductive Toxicology, National Center for Toxicological Research, Jefferson, Arkansas 72079, USA
Toxicol Sci 54:138-53. 2000..The current study provides the most structurally diverse ER RBA data set with the widest range of RBA values published to date...
- QSAR models using a large diverse set of estrogensL M Shi
ROW Sciences Inc, Jefferson, Arkansas 72079, USA
J Chem Inf Comput Sci 41:186-95. 2001....
- An integrated "4-phase" approach for setting endocrine disruption screening priorities--phase I and II predictions of estrogen receptor binding affinityL Shi
R O W Sciences, Inc, Jefferson, AR 72079, USA
SAR QSAR Environ Res 13:69-88. 2002..We believe that the same integrated scheme will be equally applicable to endpoints of other endocrine disrupting mechanisms, e.g. androgen receptor binding...
- Threshold analysis of selected dose-response data for endocrine active chemicalsR M Blair
Division of Genetic and Reproductive Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA
APMIS 109:198-208. 2001..The normalized data demonstrated a good fit to the modified Michaelis-Menten equation. These results indicate that a variety of biological responses fit the modified Michaelis-Menten equation, which does not have a threshold dose term...