Bhaskar Bhattacharya

Summary

Affiliation: Food and Drug Administration
Country: USA

Publications

  1. pmc Comparison of the gene expression profile of undifferentiated human embryonic stem cell lines and differentiating embryoid bodies
    Bhaskar Bhattacharya
    Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    BMC Dev Biol 5:22. 2005
  2. ncbi request reprint Analysis of the quality of contact-pin fabricated oligonucleotide microarrays
    Amy X Yang
    Tumor Vaccines and Biotechnology Branch, Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, RM2NN20, Building 29B, 8800 Rockville Pike, Bethesda, MD 20892, USA
    Mol Biotechnol 34:303-15. 2006
  3. ncbi request reprint Development of a focused microarray to assess human embryonic stem cell differentiation
    Amy X Yang
    Laboratory of Molecular Tumor Biology, Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Stem Cells Dev 14:270-84. 2005
  4. ncbi request reprint Gene expression in human embryonic stem cell lines: unique molecular signature
    Bhaskar Bhattacharya
    Laboratory of Molecular Tumor Biology, Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Blood 103:2956-64. 2004
  5. ncbi request reprint Comparisons between transcriptional regulation and RNA expression in human embryonic stem cell lines
    Audrey Player
    Advanced Technology Center, Microarray Facility, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Stem Cells Dev 15:315-23. 2006
  6. pmc Venezuelan equine encephalitis virus infection causes modulation of inflammatory and immune response genes in mouse brain
    Anuj Sharma
    Centre for Combat Casualty and Life Sustainment Research, Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
    BMC Genomics 9:289. 2008
  7. ncbi request reprint A review of gene expression profiling of human embryonic stem cell lines and their differentiated progeny
    Bhaskar Bhattacharya
    Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Curr Stem Cell Res Ther 4:98-106. 2009
  8. ncbi request reprint Properties of pluripotent human embryonic stem cells BG01 and BG02
    Xianmin Zeng
    Development and Plasticity Section, Cellular Neurobiology Research Branch, National Institute on Drug Abuse, Department of Health and Human Services, Baltimore, Maryland 21224, USA
    Stem Cells 22:292-312. 2004
  9. ncbi request reprint Designing, testing, and validating a microarray for stem cell characterization
    Yongquan Luo
    Stem Cell Biology Unit, Laboratory of Neurosciences, National Institute on Aging, Baltimore, MD, USA
    Methods Mol Biol 331:241-66. 2006

Detail Information

Publications9

  1. pmc Comparison of the gene expression profile of undifferentiated human embryonic stem cell lines and differentiating embryoid bodies
    Bhaskar Bhattacharya
    Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    BMC Dev Biol 5:22. 2005
    ....
  2. ncbi request reprint Analysis of the quality of contact-pin fabricated oligonucleotide microarrays
    Amy X Yang
    Tumor Vaccines and Biotechnology Branch, Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, RM2NN20, Building 29B, 8800 Rockville Pike, Bethesda, MD 20892, USA
    Mol Biotechnol 34:303-15. 2006
    ..Taken together, these results indicate that the quality of spotted oligonucleotide arrays should be assessed by at least two methods, autofluorescence and 9-mer hybridization before arrays are used for hybridization experiments...
  3. ncbi request reprint Development of a focused microarray to assess human embryonic stem cell differentiation
    Amy X Yang
    Laboratory of Molecular Tumor Biology, Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Stem Cells Dev 14:270-84. 2005
    ..We expect that the described array will be extremely useful in evaluating the extent of differentiation and the state of the hESC-derived population utilized for therapeutic purposes...
  4. ncbi request reprint Gene expression in human embryonic stem cell lines: unique molecular signature
    Bhaskar Bhattacharya
    Laboratory of Molecular Tumor Biology, Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Blood 103:2956-64. 2004
    ..These results represent the first detailed characterization of undifferentiated huES cells and provide a unique set of markers to profile and better understand the biology of huES cells...
  5. ncbi request reprint Comparisons between transcriptional regulation and RNA expression in human embryonic stem cell lines
    Audrey Player
    Advanced Technology Center, Microarray Facility, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Stem Cells Dev 15:315-23. 2006
    ..Collectively, these data provide insight into the relationship between gene expression and transcriptional regulation, resulting in a reliable list of genes associated with hESCs...
  6. pmc Venezuelan equine encephalitis virus infection causes modulation of inflammatory and immune response genes in mouse brain
    Anuj Sharma
    Centre for Combat Casualty and Life Sustainment Research, Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
    BMC Genomics 9:289. 2008
    ..Changes in gene expression were correlated with histological changes in the brain. In addition, a molecular framework of changes in gene expression associated with progression of the disease was studied...
  7. ncbi request reprint A review of gene expression profiling of human embryonic stem cell lines and their differentiated progeny
    Bhaskar Bhattacharya
    Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Curr Stem Cell Res Ther 4:98-106. 2009
    ....
  8. ncbi request reprint Properties of pluripotent human embryonic stem cells BG01 and BG02
    Xianmin Zeng
    Development and Plasticity Section, Cellular Neurobiology Research Branch, National Institute on Drug Abuse, Department of Health and Human Services, Baltimore, Maryland 21224, USA
    Stem Cells 22:292-312. 2004
    ..These data provide a detailed characterization and an initial gene expression profile for the BG01 and BG02 human ES cell lines...
  9. ncbi request reprint Designing, testing, and validating a microarray for stem cell characterization
    Yongquan Luo
    Stem Cell Biology Unit, Laboratory of Neurosciences, National Institute on Aging, Baltimore, MD, USA
    Methods Mol Biol 331:241-66. 2006
    ..Here we describe a protocol using this method to examine stem cells...