Research Topics
| Bhaskar BhattacharyaSummaryAffiliation: Food and Drug Administration Country: USA Publications
| Collaborators
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Detail Information
Publications
Comparison of the gene expression profile of undifferentiated human embryonic stem cell lines and differentiating embryoid bodiesBhaskar Bhattacharya
Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
BMC Dev Biol 5:22. 2005....
Analysis of the quality of contact-pin fabricated oligonucleotide microarraysAmy X Yang
Tumor Vaccines and Biotechnology Branch, Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, RM2NN20, Building 29B, 8800 Rockville Pike, Bethesda, MD 20892, USA
Mol Biotechnol 34:303-15. 2006..Taken together, these results indicate that the quality of spotted oligonucleotide arrays should be assessed by at least two methods, autofluorescence and 9-mer hybridization before arrays are used for hybridization experiments...
Development of a focused microarray to assess human embryonic stem cell differentiationAmy X Yang
Laboratory of Molecular Tumor Biology, Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
Stem Cells Dev 14:270-84. 2005..We expect that the described array will be extremely useful in evaluating the extent of differentiation and the state of the hESC-derived population utilized for therapeutic purposes...
Gene expression in human embryonic stem cell lines: unique molecular signatureBhaskar Bhattacharya
Laboratory of Molecular Tumor Biology, Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
Blood 103:2956-64. 2004..These results represent the first detailed characterization of undifferentiated huES cells and provide a unique set of markers to profile and better understand the biology of huES cells...
Comparisons between transcriptional regulation and RNA expression in human embryonic stem cell linesAudrey Player
Advanced Technology Center, Microarray Facility, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Stem Cells Dev 15:315-23. 2006..Collectively, these data provide insight into the relationship between gene expression and transcriptional regulation, resulting in a reliable list of genes associated with hESCs...
Venezuelan equine encephalitis virus infection causes modulation of inflammatory and immune response genes in mouse brainAnuj Sharma
Centre for Combat Casualty and Life Sustainment Research, Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
BMC Genomics 9:289. 2008..Changes in gene expression were correlated with histological changes in the brain. In addition, a molecular framework of changes in gene expression associated with progression of the disease was studied...
A review of gene expression profiling of human embryonic stem cell lines and their differentiated progenyBhaskar Bhattacharya
Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
Curr Stem Cell Res Ther 4:98-106. 2009....
Properties of pluripotent human embryonic stem cells BG01 and BG02Xianmin Zeng
Development and Plasticity Section, Cellular Neurobiology Research Branch, National Institute on Drug Abuse, Department of Health and Human Services, Baltimore, Maryland 21224, USA
Stem Cells 22:292-312. 2004..These data provide a detailed characterization and an initial gene expression profile for the BG01 and BG02 human ES cell lines...
Designing, testing, and validating a microarray for stem cell characterizationYongquan Luo
Stem Cell Biology Unit, Laboratory of Neurosciences, National Institute on Aging, Baltimore, MD, USA
Methods Mol Biol 331:241-66. 2006..Here we describe a protocol using this method to examine stem cells...
